51
51
Oct 12, 2014
10/14
by
Chen, Hongfei; Xia, Yun; Zhu, Binbin; Hu, Xiawei; Xu, Shihao; Chen, Limei; Papadimos, Thomas J; Wang, Wantie; Wang, Quanguang; Xu, Xuzhong
texts
eye 51
favorite 0
comment 0
This article is from BMC Anesthesiology , volume 14 . Abstract Background: The reversal efficacy of 2% lipid emulsion in cardiac asystole induced by different concentrations of bupivacaine is poorly defined and needs to be determined. Methods: Forty-two male Sprague–Dawley rats were randomly divided into seven groups: B40, B60, B80, B100, B120, B140 and B160, n = 6. The Langendorff isolated heart perfusion model was used, which consisted of a balanced perfusion with Krebs-Henseleit...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118607
96
96
Oct 10, 2014
10/14
by
Fioravanti, Mario; Nakashima, Taku; Xu, Jun; Garg, Amit
texts
eye 96
favorite 0
comment 0
This article is from BMJ Open , volume 4 . Abstract Objective: To evaluate the safety profile of nicergoline compared with placebo and other active agents from published randomised controlled trials. Design: Systematic review and meta-analysis of nicergoline compared with placebo and other active agents across various indications. Data sources: MEDLINE, Medline-in-process, Cochrane, EMBASE, EMBASE alerts, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120366
76
76
Oct 7, 2014
10/14
by
Jiang, Ke; Li, Yingchun; Zhu, Qiumin; Xu, Jiansheng; Wang, Yupeng; Deng, Wuguo; Liu, Quentin; Zhang, Guirong; Meng, Songshu
texts
eye 76
favorite 0
comment 0
This article is from BMC Cancer , volume 14 . Abstract Background: Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells. Methods: The effect of NDV/FMW infection on autophagy machinery in A549...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141091
60
60
Oct 4, 2014
10/14
by
LI, GUO-CAI; XU, YONG; ZHANG, YU-CHUN; ZHANG, FANG-CHENG; WANG, QI; MA, QING-JIU
texts
eye 60
favorite 0
comment 0
This article is from Oncology Letters , volume 8 . Abstract Surgery for digestive tract disease predominantly consists of reconstruction and anastomosis. Due to the difficult location, anastomosis is extremely challenging and the risk of complication increases accordingly. Traditional manual anastomosis and the application of a stapling device are insufficient. Therefore, the aim of this study was to investigate the feasibility and safety of a novel manual method in a difficult anastomotic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156267
113
113
Oct 11, 2014
10/14
by
Sampasa-Kanyinga, Hugues; Roumeliotis, Paul; Xu, Hao
texts
eye 113
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Purpose: The negative effects of peer aggression on mental health are key issues for public health. The purpose of this study was to examine the associations between cyberbullying and school bullying victimization with suicidal ideation, plans and attempts among middle and high school students, and to test whether these relationships were mediated by reports of depression. Methods: Data for this study are from the 2011 Eastern Ontario Youth...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116124
58
58
Oct 12, 2014
10/14
by
Xavier, Basil Britto; Sabirova, Julia; Pieter, Moons; Hernalsteens, Jean-Pierre; de Greve, Henri; Goossens, Herman; Malhotra-Kumar, Surbhi
texts
eye 58
favorite 0
comment 0
This article is from BMC Research Notes , volume 7 . Abstract Background: De novo genome assembly can be challenging due to inherent properties of the reads, even when using current state-of-the-art assembly tools based on de Bruijn graphs. Often users are not bio-informaticians and, in a black box approach, utilise assembly parameters such as contig length and N50 to generate whole genome sequences, potentially resulting in mis-assemblies. Findings: Utilising several assembly tools based on de...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118782
56
56
Oct 11, 2014
10/14
by
Xie, Ni; Mou, Lisha; Yuan, Jianhui; Liu, Wenlan; Deng, Tingting; Li, Zigang; Jin, Yi; Hu, Zhangli
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: The BCRP/ABCG2 transporter, which mediates drug resistance in many types of cells, depends on energy provided by ATP hydrolysis. Here, a retrovirus encoding a shRNA targeting the ATP-binding domain of this protein was used to screen for highly efficient agents that could reverse drug resistance and improve cell sensitivity to drugs, thus laying the foundation for further studies and applications. Methodology/Principal Findings: To...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116202
76
76
Oct 8, 2014
10/14
by
Xu, Xinxiu; Yu, Xiongjie; He, Jufang; Nelken, Israel
texts
eye 76
favorite 0
comment 0
This article is from Frontiers in Neural Circuits , volume 8 . Abstract The ability to detect unexpected or deviant events in natural scenes is critical for survival. In the auditory system, neurons from the midbrain to cortex adapt quickly to repeated stimuli but this adaptation does not fully generalize to other rare stimuli, a phenomenon called stimulus-specific adaptation (SSA). Most studies of SSA were conducted with pure tones of different frequencies, and it is by now well-established...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115630
53
53
Oct 10, 2014
10/14
by
Yao, Xuan; Hou, Sarina; Zhang, Duo; Xia, Hongfeng; Wang, Yu-Cheng; Jiang, Jingjing; Yin, Huiyong; Ying, Hao
texts
eye 53
favorite 0
comment 0
This article is from Cell & Bioscience , volume 4 . Abstract Background: Thyroid hormones (THs) are potent hormones modulating liver lipid homeostasis. The perturbation of lipid homeostasis is a hallmark of non-alcoholic fatty liver disease (NAFLD), a very common liver disorder. It was reported that NAFLD patients were associated with higher incidence of hypothyroidism. However, whether abnormal thyroid function contributes to the pathogenesis of NAFLD remains unclear. Results: We used in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124172
60
60
Oct 8, 2014
10/14
by
Zhou, Douglas; Zhang, Yaoyu; Xiao, Yanyang; Cai, David
texts
eye 60
favorite 0
comment 0
This article is from Frontiers in Computational Neuroscience , volume 8 . Abstract Granger causality (GC) is a powerful method for causal inference for time series. In general, the GC value is computed using discrete time series sampled from continuous-time processes with a certain sampling interval length τ, i.e., the GC value is a function of τ. Using the GC analysis for the topology extraction of the simplest integrate-and-fire neuronal network of two neurons, we discuss behaviors of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115622
110
110
Oct 10, 2014
10/14
by
Zhou, Lili; Zheng, Shouyan; Xiao, Qiuyan; Ren, Luo; Xie, Xiaohong; Luo, Jian; Wang, Lijia; Huang, Ailong; Liu, Wei; Liu, Enmei
texts
eye 110
favorite 0
comment 0
This article is from BMC Infectious Diseases , volume 14 . Abstract Background: Human bocavirus is a newly discovered parvovirus. Multiple studies have confirmed the presence of human bocavirus1 (HBoV1) in respiratory tract samples of children. The viral load, presentation of single detection and its role as a causative agent of severe respiratory tract infections have not been thoroughly elucidated. Methods: We investigated the presence of HBoV1 by quantitative polymerase chain reaction (PCR)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125703
