67
67
Oct 12, 2014
10/14
by
Aahlin, Eirik K; von Meyenfeldt, Maarten; Dejong, Cornelius HC; Ljungqvist, Olle; Fearon, Kenneth C; Lobo, Dileep N; Demartines, Nicolas; Revhaug, Arthur; Wigmore, Stephen J; Lassen, Kristoffer
texts
eye 67
favorite 0
comment 0
This article is from Perioperative Medicine , volume 3 . Abstract Background: The aim of this study was to survey the relative importance of postoperative recovery targets and perioperative care items, as perceived by a large group of international dedicated professionals. Methods: A questionnaire with eight postoperative recovery targets and 13 perioperative care items was mailed to participants of the first international Enhanced Recovery After Surgery (ERAS) congress and to authors of papers...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118075
57
57
Oct 8, 2014
10/14
by
Bala, Margarita; Ronchi, Cristina L; Pichl, Josef; Wild, Vanessa; Kircher, Stefan; Allolio, Bruno; Hahner, Stefanie
texts
eye 57
favorite 0
comment 0
This article is from BMC Endocrine Disorders , volume 14 . Abstract Background: Kaposi sarcoma (KS) is a malignant disease most commonly diagnosed in the setting of a human immunodeficiency virus (HIV) infection and in patients receiving immunosuppressive treatment. Pulmonary KS has never been reported in association with endogenous Cushing’s syndrome (CS). Case presentation: A 60-year-old woman presented with symptoms and signs of CS. Adrenal CS was confirmed by standard biochemical...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128825
110
110
Oct 7, 2014
10/14
by
Bortoletto, Carolina Carvalho; Cordeiro da Silva, Fernanda; Silva, Paula Fernanda da Costa; Leal de Godoy, Camila Haddad; Albertini, Regiane; Motta, Lara J; Mesquita-Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos; Romano, Renata; Bussadori, Sandra Kalil
texts
eye 110
favorite 0
comment 0
This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] The aim of the present study was to evaluate the effect of a biteplate on the cranio-cervical posture of children with bruxism. [Subjects and Methods] Twelve male and female children aged six to 10 years with a diagnosis of bruxism participated in this study. The children used a biteplate during sleep for 30 days and were submitted to three postural evaluations: initial, immediately following placement...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135211
43
43
Oct 11, 2014
10/14
by
Botman, Daniel; Rottinger, Eric; Martindale, Mark Q.; de Jong, Johann; Kaandorp, Jaap A.
texts
eye 43
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: The starlet sea anemone Nematostella vectensis is a diploblastic cnidarian that expresses a set of conserved genes for gut formation during its early development. During the last decade, the spatial distribution of many of these genes has been visualized with RNA hybridization or protein immunolocalization techniques. However, due to N. vectensis' curved and changing morphology, quantification of these spatial data is problematic....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116165
50
50
Oct 8, 2014
10/14
by
Broek, Jantine AC; Guest, Paul C; Rahmoune, Hassan; Bahn, Sabine
texts
eye 50
favorite 0
comment 0
This article is from Molecular Autism , volume 5 . Abstract Background: Autism is a neurodevelopmental disorder characterized by impaired language, communication and social skills. Although genetic studies have been carried out in this field, none of the genes identified have led to an explanation of the underlying causes. Here, we have investigated molecular alterations by proteomic profiling of post mortem brain samples from autism patients and controls. The analysis focussed on prefrontal...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131484
43
43
Oct 2, 2014
10/14
by
Caseley, Emily A.; Muench, Stephen P.; Roger, Sebastien; Mao, Hong-Ju; Baldwin, Stephen A.; Jiang, Lin-Hua
texts
eye 43
favorite 0
comment 0
This article is from International Journal of Molecular Sciences , volume 15 . Abstract P2X receptors are Ca2+-permeable cationic channels in the cell membranes, where they play an important role in mediating a diversity of physiological and pathophysiological functions of extracellular ATP. Mammalian cells express seven P2X receptor genes. Single nucleotide polymorphisms (SNPs) are widespread in the P2RX genes encoding the human P2X receptors, particularly the human P2X7 receptor. This article...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159798
67
67
Oct 8, 2014
10/14
by
Chen, Wei; Liu, Bo; Wang, Li-qiong; Ren, Jun; Liu, Jian-ping
texts
eye 67
favorite 0
comment 0
This article is from BMC Complementary and Alternative Medicine , volume 14 . Abstract Background: Many Chinese patent medicines (CPMs) have been authorized by the Chinese State of Food and Drug Administration for the treatment of the common cold. A number of clinical trials have been conducted and published. However, there is no systematic review or meta-analysis on their efficacy and safety for the common cold to justify their clinical use. Methods: We searched CENTRAL, MEDLINE, EMBASE,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129119
54
54
Oct 8, 2014
10/14
by
Cuevas, Carlos A.; Notario, Alberto; Adame, Jose Antonio; Hilboll, Andreas; Richter, Andreas; Burrows, John P.; Saiz-Lopez, Alfonso
texts
eye 54
favorite 0
comment 0
This article is from Scientific Reports , volume 4 . Abstract We report on the evolution of tropospheric nitrogen dioxide (NO2) over Spain, focusing on the densely populated cities of Barcelona, Bilbao, Madrid, Sevilla and Valencia, during 17 years, from 1996 to 2012. This data series combines observations from in-situ air quality monitoring networks and the satellite-based instruments GOME and SCIAMACHY. The results in these five cities show a smooth decrease in the NO2 concentrations of ~2%...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115208
50
50
Oct 8, 2014
10/14
by
Dean-Ben, Xose Luis; Bay, Erwin; Razansky, Daniel
texts
eye 50
favorite 0
comment 0
This article is from Scientific Reports , volume 4 . Abstract The breakthrough capacity of optoacoustics for three-dimensional visualization of dynamic events in real time has been recently showcased. Yet, efficient spectral unmixing for functional imaging of entire volumetric regions is significantly challenged by motion artifacts in concurrent acquisitions at multiple wavelengths. Here, we introduce a method for simultaneous acquisition of multispectral volumetric datasets by introducing a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115207
24
24
Oct 5, 2014
10/14
by
Diaz-Perez, Julio A.; Raju, Sharat; Echeverri, Jorge H.
texts
eye 24
favorite 0
comment 0
This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Learning pathology is fundamental for a successful medical practice. In recent years, medical education has undergone a profound transformation toward the development of an integrated curriculum incorporating both basic science and clinical material. Simultaneously, there has been a shift from a magisterial teaching approach to one centered around problem-based learning. Now-a-days, informatics tools are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141419
75
75
Oct 11, 2014
10/14
by
Diekhof, Esther Kristina; Wittmer, Susanne; Reimers, Luise
texts
eye 75
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Parochial altruism, defined as increased ingroup favoritism and heightened outgroup hostility, is a widespread feature of human societies that affects altruistic cooperation and punishment behavior, particularly in intergroup conflicts. Humans tend to protect fellow group members and fight against outsiders, even at substantial costs for themselves. Testosterone modulates responses to competition and social threat, but its exact role in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116333
70
70
Oct 11, 2014
10/14
by
Egekwu, Noble; Sonenshine, Daniel E.; Bissinger, Brooke W.; Roe, R. Michael
texts
eye 70
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods. However, for molecular processes, it was more successful for the Illumina samples than for 454 samples. Functional assignments of transcripts predicting neuropeptides, neuropeptide receptors, neurotransmitter receptors and other...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116169
96
96
Oct 11, 2014
10/14
by
Ferrara, Maria Antonietta; Dardano, Principia; De Stefano, Luca; Rea, Ilaria; Coppola, Giuseppe; Rendina, Ivo; Congestri, Roberta; Antonucci, Alessandra; De Stefano, Mario; De Tommasi, Edoardo
texts
eye 96
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Some natural structures show three-dimensional morphologies on the micro- and nano- scale, characterized by levels of symmetry and complexity well far beyond those fabricated by best technologies available. This is the case of diatoms, unicellular microalgae, whose protoplasm is enclosed in a nanoporous microshell, made of hydrogenated amorphous silica, called frustule. We have studied the optical properties of Arachnoidiscus sp. single valves...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116236
52
52
Oct 11, 2014
10/14
by
Fischer, Sebastian; Wiemer, Anita; Diedrich, Laura; Moock, Jorn; Rossler, Wulf
texts
eye 52
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract We suggest that interactions with strangers at work influence the likelihood of depressive disorders, as they serve as an environmental stressor, which are a necessary condition for the onset of depression according to diathesis-stress models of depression. We examined a large dataset (N = 76,563 in K = 196 occupations) from the German pension insurance program and the Occupational Information Network dataset on occupational...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116212
77
77
Oct 8, 2014
10/14
by
Foret, Michael R.; Sandstrom, Richard S.; Rhodes, Christopher T.; Wang, Yufeng; Berger, Mitchel S.; Lin, Chin-Hsing Annie
texts
eye 77
favorite 0
comment 0
This article is from Frontiers in Genetics , volume 5 . Abstract Histone 3 Lysine 9 (H3K9) methylation is known to be associated with pericentric heterochromatin and important in genomic stability. In this study, we show that trimethylation at H3K9 (H3K9me3) is enriched in an adult neural stem cell niche- the subventricular zone (SVZ) on the walls of the lateral ventricle in both rodent and non-human primate baboon brain. Previous studies have shown that there is significant correlation between...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115620
51
51
Oct 11, 2014
10/14
by
Gallego, Pamela K; Burris, Jessica L; Rivera, Susan M
texts
eye 51
favorite 0
comment 0
This article is from Journal of Neurodevelopmental Disorders , volume 6 . Abstract Background: Fragile X syndrome (FXS) results from a trinucleotide repeat expansion (full mutation >200 cytosine-guanine-guanine (CGG) repeats) in the FMR1 gene, leading to a reduction or absence of the gene’s protein product, fragile X mental retardation protein (FMRP), ultimately causing cognitive and behavioral impairments that are characteristic of the syndrome. In our previous work with infants and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121307
56
56
Oct 11, 2014
10/14
by
Golden-Mason, Lucy; Hahn, Young S.; Strong, Michael; Cheng, Linling; Rosen, Hugo R.
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Hepatitis C viral (HCV) proteins, including core, demonstrate immuno-modulatory properties; however, the effect of extracellular core on natural killer (NK) cells has not previously been investigated. Aims: To characterise NKs in acute HCV infection over time, and, to examine the effect of exogenous HCV-core protein on NK cell phenotype and function. Methods: Acute HCV patients (n = 22), including 10 subjects who spontaneously...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116173
65
65
Oct 7, 2014
10/14
by
Grigsby, Jim; Cornish, Kim; Hocking, Darren; Kraan, Claudine; Olichney, John M; Rivera, Susan M; Schneider, Andrea; Sherman, Stephanie; Wang, Jun Yi; Yang, Jin-Chen
texts
eye 65
favorite 0
comment 0
This article is from Journal of Neurodevelopmental Disorders , volume 6 . Abstract The fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting a subset of carriers of the FMR1 (fragile X mental retardation 1) premutation. Penetrance and expression appear to be significantly higher in males than females. Although the most obvious aspect of the phenotype is the movement disorder that gives FXTAS its name, the disorder is also accompanied by...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135346
59
59
Oct 10, 2014
10/14
by
Hafstrom, Ingiald; Engvall, Inga-Lill; Ronnelid, Johan; Boonen, Annelies; van der Heijde, Desiree; Svensson, Bjorn
texts
eye 59
favorite 0
comment 0
This article is from BMJ Open , volume 4 . Abstract Objective: To analyse if predictors of radiographic progression differ between patients treated with or without prednisolone in early rheumatoid arthritis (RA). Radiographs of hands and feet were assessed using the modified Sharp/van der Heijde score and radiographic progression was defined as an increase in the total Sharp score above 5.8 (the smallest detectable change). Design: Prospective, randomised study of patients with early RA....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120364
64
64
Oct 11, 2014
10/14
by
Harper, Diane M.; Else, Britney M.; Bartley, Mitchell J.; Arey, Anne M.; Barnett, Angela L.; Rosemergey, Beth E.; Paynter, Christopher A.; Verdenius, Inge; Harper, Sean M.; Harris, George D.; Groner, Jennifer A.; Malnar, Gerard J.; Wall, Jeffrey; Bonham, Aaron J.
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Objectives: Obesity adversely inhibits antibody response to vaccination. Three doses of HPV4 may or may not provide adequate long term protection against HPV 16/18 in obese females. The aim of this study was to determine whether adherence to HPV4 vaccination in a safety net population was reduced with increasing body mass index (BMI). Methods: We designed a historical prospective study evaluating the number and dates of HPV4 dosing that...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116139
59
59
Oct 7, 2014
10/14
by
Hershler, Robert; Ratcliffe, Victoria; Liu, Hsiu-Ping; Lang, Brian; Hay, Claire
texts
eye 59
favorite 0
comment 0
This article is from ZooKeys . Abstract AbstractWe describe two new species of springsnails (genus Pyrgulopsis) for populations from the middle Fork and upper East Fork of the Gila River Basin (New Mexico) that had been previously identified as P. gilae. We also restrict P. gilae to its originally circumscribed geographic range which consists of a short reach of the East Fork Gila River and a single spring along the Gila River (below the East Fork confluence). These three species form...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137299
65
65
Oct 11, 2014
10/14
by
Horacio, Andreia N.; Lopes, Joana P.; Ramirez, Mario; Melo-Cristino, Jose
texts
eye 65
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract There is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci causing NIPP in adults to determine recent changes in serotype prevalence, the potential coverage of pneumococcal vaccines and changes in antimicrobial resistance. Serotypes and antimicrobial susceptibility profiles of a sample of 1300 isolates recovered from adult patients (≥18 yrs) between 1999 and 2011...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116175
55
55
Oct 8, 2014
10/14
by
Hsu, Clarissa; Sherman, Karen J; Eaves, Emery R; Turner, Judith A; Cherkin, Daniel C; Cromp, DeAnn; Schafer, Lisa; Ritenbaugh, Cheryl
texts
eye 55
favorite 0
comment 0
This article is from BMC Complementary and Alternative Medicine , volume 14 . Abstract Background: Positive patient expectations are often believed to be associated with greater benefits from complementary and alternative medicine (CAM) treatments. However, clinical studies of CAM treatments for chronic pain have not consistently supported this assumption, possibly because of differences in definitions and measures of expectations. The goal of this qualitative paper is to provide new...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129105
55
55
Oct 11, 2014
10/14
by
Hu, Xiaowen; Yi, Eunhee S.; Ryu, Jay H.
texts
eye 55
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Aspiration can cause a diverse spectrum of pulmonary disorders some of which can lead to death but can be difficult to diagnose. Patients and Methods: The medical records and autopsy findings of 57 consecutive patients in whom aspiration was the immediate cause of death at Mayo Clinic (Rochester, MN, USA) over a 9-yr period, from January 1 2004 to December 31 2012 were analyzed. Results: The median age at death was 72 years (range,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116222
95
95
Oct 11, 2014
10/14
by
Hui, Fengli; Ren, Yongcheng; Chen, Liang; Li, Ying; Zhang, Lin; Niu, Qiuhong
texts
eye 95
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Four strains of a novel ascomycetous yeast species were recovered from the frass of wood-boring beetles collected from the Baotianman Nature Reserve and the Laojieling Nature Reserve in Henan Province, China. This species produced unconjugated and deliquescent asci with hemispheroid or helmet-shaped ascospores. Analysis of gene sequences for the D1/D2 domain of the large subunit (LSU) rRNA, as well as analysis of concatenated gene sequences...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116224
51
51
Oct 9, 2014
10/14
by
Hwang, Yong Il; Park, Yong Bum; Oh, Yeon Mok; Lee, Ji Hyun; Kim, Tae Hyung; Yoo, Kwang Ha; Yoon, Hyoung Kyu; Rhee, Chin Kook; Kim, Deog Kyeom; Shin, Kyeong Cheol; Lee, Sang Yeub; Jung, Ki-Suck
texts
eye 51
favorite 0
comment 0
This article is from Journal of Korean Medical Science , volume 29 . Abstract The purpose of this study was to compare the Korean COPD guideline to GOLD consensus report in terms of acute exacerbation. A total of 361 patients were enrolled in this study, and 16.9% of them experienced acute exacerbation during the follow-up. A total of 6.3% of patients in GOLD A, 9.5% in GOLD B, 7.7% in GOLD C and 17.0% of GOLD D experienced exacerbation during the first year of follow-up, respectively (P=0.09)....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129203
99
99
Oct 8, 2014
10/14
by
Ioannou, Christos A.; Romero, Julian
texts
eye 99
favorite 0
comment 0
This article is from Frontiers in Neuroscience , volume 8 . Abstract We use the self-tuning Experience Weighted Attraction model with repeated-game strategies as a computer testbed to examine the relative frequency, speed of convergence and progression of a set of repeated-game strategies in four symmetric 2 × 2 games: Prisoner's Dilemma, Battle of the Sexes, Stag-Hunt, and Chicken. In the Prisoner's Dilemma game, we find that the strategy with the most occurrences is the “Grim-Trigger.”...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115627
137
137
Oct 6, 2014
10/14
by
Kandziora, Maja; Reissig, Hans-Ulrich
texts
eye 137
favorite 1
comment 0
This article is from Beilstein Journal of Organic Chemistry , volume 10 . Abstract An approach to β-D-2-aminotalose- and β-D-2-aminoidose-configured carbohydrate mimetics bearing a phenyl substituent is described. Unnatural divalent rigid p-terphenyl-linked C-aryl glycosides with 2.0 nm dimension are available using Suzuki cross-couplings. The key compound, a p-bromophenyl-substituted 1,2-oxazine, was prepared by a stereoselective [3 + 3]-cyclization of a D-isoascorbic acid-derived...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142845
48
48
Oct 10, 2014
10/14
by
Kiani, Mohammad Javad; Harun, Fauzan Khairi Che; Ahmadi, Mohammad Taghi; Rahmani, Meisam; Saeidmanesh, Mahdi; Zare, Moslem
texts
eye 48
favorite 0
comment 0
This article is from Nanoscale Research Letters , volume 9 . Abstract Graphene is an attention-grabbing material in electronics, physics, chemistry, and even biology because of its unique properties such as high surface-area-to-volume ratio. Also, the ability of graphene-based materials to continuously tune charge carriers from holes to electrons makes them promising for biological applications, especially in lipid bilayer-based sensors. Furthermore, changes in charged lipid membrane properties...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125348
43
43
Oct 8, 2014
10/14
by
Lohr, Verena; Hadicke, Oliver; Genzel, Yvonne; Jordan, Ingo; Buntemeyer, Heino; Klamt, Steffen; Reichl, Udo
texts
eye 43
favorite 0
comment 0
This article is from BMC Biotechnology , volume 14 . Abstract Background: In human vaccine manufacturing some pathogens such as Modified Vaccinia Virus Ankara, measles, mumps virus as well as influenza viruses are still produced on primary material derived from embryonated chicken eggs. Processes depending on primary cell culture, however, are difficult to adapt to modern vaccine production. Therefore, we derived previously a continuous suspension cell line, AGE1.CR.pIX, from muscovy duck and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124504
64
64
Oct 11, 2014
10/14
by
Lu, Ning; Karlsen, Tine V.; Reed, Rolf K.; Kusche-Gullberg, Marion; Gullberg, Donald
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract We have previously shown that fibroblast expression of α11β1 integrin stimulates A549 carcinoma cell growth in a xenograft tumor model. To understand the molecular mechanisms whereby a collagen receptor on fibroblast can regulate tumor growth we have used a 3D heterospheroid system composed of A549 tumor cells and fibroblasts without (α11+/+) or with a deletion (α11-/-) in integrin α11 gene. Our data show that α11-/-/A549 spheroids are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116160
52
52
Oct 11, 2014
10/14
by
Lundberg, Mathias; Curbo, Sophie; Reiser, Kathrin; Masterman, Thomas; Braesch-Andersen, Sten; Arestrom, Irene; Ahlborg, Niklas
texts
eye 52
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Thioredoxin-1 (Trx1) is a protein antioxidant involved in major cellular processes. Increased plasma levels of Trx1 have been associated with human diseases suggesting that Trx1 is a marker for oxidative stress with putative clinical use. However, the reported mean levels of Trx1 in the control cohorts vary a hundred-fold between studies (0.8–87 ng/ml), possibly due to methodological differences between the capture ELISA used in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116216
92
92
Oct 3, 2014
10/14
by
Nombela, Cristina; Rowe, James B.; Winder-Rhodes, Sophie E.; Hampshire, Adam; Owen, Adrian M.; Breen, David P.; Duncan, Gordon W.; Khoo, Tien K.; Yarnall, Alison J.; Firbank, Michael J.; Chinnery, Patrick F.; Robbins, Trevor W.; O'Brien, John T.; Brooks, David J.; Burn, David J.; Barker, Roger A.
texts
eye 92
favorite 0
comment 0
This article is from Brain , volume 137 . Abstract See Dujardin (doi:10.1093/brain/awu218) for a scientific commentary on this article. Nombela et al. present data from the ICICLE-PD study of cognition in newly diagnosed Parkinson’s disease. Consistent with the ‘Dual Syndrome’ hypothesis, impairments in executive function reflect a frontal dopaminergic syndrome modulated by COMT genotype, while visuospatial and memory deficits reflect disruption of temporo-parietal systems modulated by...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163033
56
56
Oct 11, 2014
10/14
by
Pisano, Fabio; Heine, Wiebke; Rosenheinrich, Maik; Schweer, Janina; Nuss, Aaron M.; Dersch, Petra
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The two-component regulatory system PhoP/PhoQ has been shown to (i) control expression of virulence-associated traits, (ii) confer survival and growth within macrophages and (iii) play a role in Yersinia infections. However, the influence of PhoP on virulence varied greatly between different murine models of infection and its role in natural oral infections with frequently used representative isolates of Y. pseudotuberculosis was unknown. To...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116203
17
17
Oct 5, 2014
10/14
by
Quinn, Andrew M.; Klepeis, Veronica E.; Mandelker, Diana L.; Platt, Mia Y.; Rao, Luigi K. F.; Riedlinger, Gregory; Baron, Jason M.; Brodsky, Victor; Kim, Ji Yeon; Lane, William; Lee, Roy E.; Levy, Bruce P.; McClintock, David S.; Beckwith, Bruce A.; Kuo, Frank C.; Gilbertson, John R.
texts
eye 17
favorite 0
comment 0
This article is from Journal of Pathology Informatics , volume 5 . Abstract The Partners HealthCare system's Clinical Fellowship in Pathology Informatics (Boston, MA, USA) faces ongoing challenges to the delivery of its core curriculum in the forms of: (1) New classes of fellows annually with new and varying educational needs and increasingly fractured, enterprise-wide commitments; (2) taxing electronic health record (EHR) and laboratory information system (LIS) implementations; and (3)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141423
18
18
Oct 4, 2014
10/14
by
Raddaoui, Emad; Alhamad, Esam H; Zaidi, Shaesta Naseem; Al-Habeeb, Fatmah F; Arafah, Maha
texts
eye 18
favorite 0
comment 0
This article is from CytoJournal , volume 11 . Abstract Objective:: The objective of this study is to evaluate the cytological accuracy of endobronchial ultrasound-guided transbronchial fine-needle aspiration (EBUS-TFNA) of the mediastinal mass/nodular lesions. Study Design:: Over 3½ years from inception at King Khalid University Hospital, a retrospective analysis of the cytological diagnoses of all the EBUS-TFNA procedures performed in 80 patients who had mediastinal mass/nodular enlargement....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141359
69
69
Oct 8, 2014
10/14
by
Radic, Marko
texts
eye 69
favorite 0
comment 0
This article is from Frontiers in Immunology , volume 5 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115591
62
62
Oct 11, 2014
10/14
by
Rakotoarinivo, Mijoro; Dransfield, John; Bachman, Steven P.; Moat, Justin; Baker, William J.
texts
eye 62
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The establishment of baseline IUCN Red List assessments for plants is a crucial step in conservation planning. Nowhere is this more important than in biodiversity hotspots that are subject to significant anthropogenic pressures, such as Madagascar. Here, all Madagascar palm species are assessed using the IUCN Red List categories and criteria, version 3.1. Our results indicate that 83% of the 192 endemic species are threatened, nearly four...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116232
103
103
Oct 8, 2014
10/14
by
Ramey, Christopher H.; Chrysikou, Evangelia G.
texts
eye 103
favorite 0
comment 0
This article is from Frontiers in Psychology , volume 5 . Abstract The empirical link between psychopathology and creativity is often correlational and fraught with suspiciously causal interpretations. In this paper, we review research in favor of the position that certain forms of psychopathology that profoundly affect the neural substrates for rule-based thought (e.g., schizophrenia, bipolar disorder) can significantly influence the quantity of creative production. Because highly productive...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115613
89
89
Oct 8, 2014
10/14
by
Rantanen, Ville; Valori, Miko; Hautaniemi, Sampsa
texts
eye 89
favorite 0
comment 0
This article is from Frontiers in Bioengineering and Biotechnology , volume 2 . Abstract Modern microscopes produce vast amounts of image data, and computational methods are needed to analyze and interpret these data. Furthermore, a single image analysis project may require tens or hundreds of analysis steps starting from data import and pre-processing to segmentation and statistical analysis; and ending with visualization and reporting. To manage such large-scale image data analysis projects,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115631
73
73
Oct 8, 2014
10/14
by
Ray, Soham; Satya, Pratik
texts
eye 73
favorite 0
comment 0
This article is from Frontiers in Plant Science , volume 5 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115663
68
68
Oct 11, 2014
10/14
by
Raza, Haider; John, Annie; Shafarin, Jasmin
texts
eye 68
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Bacterial endotoxin lipopolysaccharide (LPS) induces the production of inflammatory cytokines and reactive oxygen species (ROS) under in vivo and in vitro conditions. Acetylsalicylic acid (ASA, aspirin) is a commonly used anti-inflammatory drug. Our aim was to study the effects of N-acetyl cysteine (NAC), an antioxidant precursor of GSH synthesis, on aspirin-sensitized macrophages treated with LPS. We investigated the effects of LPS alone and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116207
44
44
Oct 8, 2014
10/14
by
Raza, Zamaan; Errea, Ion; Oganov, Artem R.; Saitta, A. Marco
texts
eye 44
favorite 0
comment 0
This article is from Scientific Reports , volume 4 . Abstract State of the art variable composition structure prediction based on density functional theory demonstrates that two new stoichiometries of PN, PN3 and PN2, become viable at high pressure. PN3 has a skutterudite-like Immm structure and is metastable with positive phonon frequencies at pressures between 10 and 100 GPa. PN3 is metallic and is the first reported nitrogen-based skutterudite. Its metallicity arises from nitrogen p-states...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115206
85
85
Oct 11, 2014
10/14
by
Regan, Fran H.; Hockenhull, Jo; Pritchard, Joy C.; Waterman-Pearson, Avril E.; Whay, Helen R.
texts
eye 85
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: The donkey has a reputation for stoicism and its behavioural repertoire in clinical contexts is under-reported. Lack of understanding of the norms of donkey behaviour and how it may vary over time can compromise use of behavioural measures as indicators of pain or emotional state. The objective of this study was to find out whether the behaviour of working donkeys was influenced by gender, the time of day or differed between days...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116118
72
72
Oct 9, 2014
10/14
by
Rhie, Young-Jun; Lee, Kee-Hyoung; Ko, Jung Min; Lee, Woo Jung; Kim, Jung Hyun; Kim, Ho-Seong
texts
eye 72
favorite 0
comment 0
This article is from Journal of Korean Medical Science , volume 29 . Abstract Kisspeptin/G-protein couple receptor-54 (GPR54) system plays a key role in the activation of the gonadotropic axis at puberty. Central precocious puberty (CPP) is caused by the premature activation of hypothalamic gonadotropin-releasing hormone secretion. This study was aimed to identify KISS1 gene variations and to investigate the associations between KISS1 gene variations and CPP in Korean girls. All coding exons of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129205
58
58
Oct 8, 2014
10/14
by
Rigal, Adeline; Ma, Qian; Robert, Stephanie
texts
eye 58
favorite 0
comment 0
This article is from Frontiers in Plant Science , volume 5 . Abstract Plants have acquired the capacity to grow continuously and adjust their morphology in response to endogenous and external signals, leading to a high architectural plasticity. The dynamic and differential distribution of phytohormones is an essential factor in these developmental changes. Phytohormone perception is a fast but complex process modulating specific developmental reprogramming. In recent years, chemical genomics or...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115670
61
61
Oct 11, 2014
10/14
by
Robison, Bruce; Seibel, Brad; Drazen, Jeffrey
texts
eye 61
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Octopuses typically have a single reproductive period and then they die (semelparity). Once a clutch of fertilized eggs has been produced, the female protects and tends them until they hatch. In most shallow-water species this period of parental care can last from 1 to 3 months, but very little is known about the brooding of deep-living species. In the cold, dark waters of the deep ocean, metabolic processes are often slower than their...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116195
61
61
Oct 11, 2014
10/14
by
Roozendaal, Ramon; Tolboom, Jeroen; Roos, Anna; Riahi, Sarra; Theeuwsen, Jessica; Bujny, Miriam V.; Klaren, Vincent; Korse, Hans J. W. M.; Dekking, Liesbeth; Grootenhuis, Arijan; Weverling, Gerrit Jan; Koudstaal, Wouter; Goudsmit, Jaap; Radosevic, Katarina
texts
eye 61
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Current influenza vaccines are believed to confer protection against a narrow range of virus strains. The identification of broadly influenza neutralizing antibodies (bnAbs) has triggered efforts to develop vaccines providing ‘universal’ protection against influenza. Several bnAbs were isolated from humans recently vaccinated with conventional influenza vaccines, suggesting that such vaccines could, in principle, be broadly protective....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116209
30
30
Oct 5, 2014
10/14
by
Roy, Somak; Pantanowitz, Liron; Amin, Milon; Seethala, Raja R.; Ishtiaque, Ahmed; Yousem, Samuel A.; Parwani, Anil V.; Cucoranu, Ioan; Hartman, Douglas J.
texts
eye 30
favorite 0
comment 0
This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Photomicrographs in Anatomic Pathology provide a means of quickly sharing information from a glass slide for consultation, education, documentation and publication. While static image acquisition historically involved the use of a permanently mounted camera unit on a microscope, such cameras may be expensive, need to be connected to a computer, and often require proprietary software to acquire and process...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141421
73
73
Oct 9, 2014
10/14
by
Said, Sarmad; Alkhateeb, Haider; Cooper, Chad J; Rodriguez, Emmanuel; Trien, Remi; Hernandez, German T; Salameh, Hasan S
texts
eye 73
favorite 0
comment 0
This article is from International Medical Case Reports Journal , volume 7 . Abstract Introduction: Idiopathic cluster of differentiation 4 (CD4+) T-cell lymphocytopenia (ICL) is a rare non human immunodeficiency virus (HIV)-related syndrome with unclear natural history and prognosis that was first reported and defined in 1992. ICL has been observed in patients after the onset of an opportunistic infection without known immunosuppression. Case presentation: A 20-year-old Hispanic male patient...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124073