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Oct 4, 2014
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AFONSO, JULIETA; LONGATTO-FILHO, ADHEMAR; DA SILVA, VITOR MOREIRA; AMARO, TERESINA; SANTOS, LUCIO L.
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This article is from Oncology Letters , volume 8 . Abstract Urothelial bladder carcinoma (UBC) is heterogeneous in its pathology and clinical behaviour. Evaluation of prognostic and predictive biomarkers is necessary, in order to produce personalised treatment options. The present study used immunohistochemistry to evaluate UBC sections containing tumour and non-tumour areas from 76 patients, for the detection of p-mTOR, CD31 and D2-40 (blood and lymphatic vessels identification, respectively)....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156165
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Oct 12, 2014
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Aahlin, Eirik K; von Meyenfeldt, Maarten; Dejong, Cornelius HC; Ljungqvist, Olle; Fearon, Kenneth C; Lobo, Dileep N; Demartines, Nicolas; Revhaug, Arthur; Wigmore, Stephen J; Lassen, Kristoffer
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This article is from Perioperative Medicine , volume 3 . Abstract Background: The aim of this study was to survey the relative importance of postoperative recovery targets and perioperative care items, as perceived by a large group of international dedicated professionals. Methods: A questionnaire with eight postoperative recovery targets and 13 perioperative care items was mailed to participants of the first international Enhanced Recovery After Surgery (ERAS) congress and to authors of papers...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118075
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Oct 11, 2014
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Botman, Daniel; Rottinger, Eric; Martindale, Mark Q.; de Jong, Johann; Kaandorp, Jaap A.
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This article is from PLoS ONE , volume 9 . Abstract Background: The starlet sea anemone Nematostella vectensis is a diploblastic cnidarian that expresses a set of conserved genes for gut formation during its early development. During the last decade, the spatial distribution of many of these genes has been visualized with RNA hybridization or protein immunolocalization techniques. However, due to N. vectensis' curved and changing morphology, quantification of these spatial data is problematic....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116165
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Oct 11, 2014
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Calabro, Sarah R.; Maczurek, Annette E.; Morgan, Alison J.; Tu, Thomas; Wen, Victoria W.; Yee, Christine; Mridha, Auvro; Lee, Maggie; d'Avigdor, William; Locarnini, Stephen A.; McCaughan, Geoffrey W.; Warner, Fiona J.; McLennan, Susan V.; Shackel, Nicholas A.
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This article is from PLoS ONE , volume 9 . Abstract Background: The classical paradigm of liver injury asserts that hepatic stellate cells (HSC) produce, remodel and turnover the abnormal extracellular matrix (ECM) of fibrosis via matrix metalloproteinases (MMPs). In extrahepatic tissues MMP production is regulated by a number of mechanisms including expression of the glycoprotein CD147. Previously, we have shown that CD147 is expressed on hepatocytes but not within the fibrotic septa in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116334
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Oct 8, 2014
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Castellazzi, Gloria; Palesi, Fulvia; Casali, Stefano; Vitali, Paolo; Sinforiani, Elena; Wheeler-Kingshott, Claudia A. M.; D'Angelo, Egidio
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This article is from Frontiers in Neuroscience , volume 8 . Abstract In resting state fMRI (rs-fMRI), only functional connectivity (FC) reductions in the default mode network (DMN) are normally reported as a biomarker for Alzheimer's disease (AD). In this investigation we have developed a comprehensive strategy to characterize the FC changes occurring in multiple networks and applied it in a pilot study of subjects with AD and Mild Cognitive Impairment (MCI), compared to healthy controls (HC)....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115623
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Oct 11, 2014
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Chang, Yi-Shin; Owen, Julia P.; Desai, Shivani S.; Hill, Susanna S.; Arnett, Anne B.; Harris, Julia; Marco, Elysa J.; Mukherjee, Pratik
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This article is from PLoS ONE , volume 9 . Abstract Over 90% of children with Autism Spectrum Disorders (ASD) demonstrate atypical sensory behaviors. In fact, hyper- or hyporeactivity to sensory input or unusual interest in sensory aspects of the environment is now included in the DSM-5 diagnostic criteria. However, there are children with sensory processing differences who do not meet an ASD diagnosis but do show atypical sensory behaviors to the same or greater degree as ASD children. We...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116166
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Oct 7, 2014
10/14
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Chigira, Yuusuke; Takai, Tomoko; Oda, Takahiro; Dobashi, Kunio
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This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] The purpose of this study was to investigate differences in effects caused by variation in the intervention frequency of outpatient pulmonary rehabilitation, in terms of the pulmonary function, lower-limb muscle strength, exercise tolerance, and quality of life (QOL). [Subjects and Methods] A total of 36 patients with mild to severe chronic obstructive pulmonary disease (COPD) were studied. These patients...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135193
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Oct 11, 2014
10/14
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Dang, Jun; Li, Guang; Zang, Shuang; Zhang, Shuo; Yao, Lei
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This article is from Radiation Oncology (London, England) , volume 9 . Abstract Background: The rate of radiation pneumonitis (RP) for patients receiving chemoradiotherapy has been various across studies. Whether it is related to different chemotherapy schedules used in combination with radiation therapy were evaluated in this study. New factors associated with RP were also investigated. Methods and materials: A total of 369 consecutive patients with Stage III non small cell lung cancer treated...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120001
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Oct 11, 2014
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Davis, Michael S.; Bonen, Arend; Snook, Laelie A.; Jain, Swati S.; Bartels, Kenneth; Geor, Raymond; Hueffer, Karsten
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This article is from PLoS ONE , volume 9 . Abstract Endurance exercise relies on transsarcolemmal flux of substrates in order to avoid depletion of intramuscular reserves. Previous studies of endurance trained sled dogs have shown a remarkable capacity of these dogs to adapt rapidly to endurance exercise by decreasing the utilization of intramuscular reserves. The current study tested the hypothesis that the dogs' glycogen-sparing phenotype is due to increased sarcolemmal transport of glucose...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116179
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Oct 10, 2014
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Dawson, Anna M; Taylor, Rachael W; Williams, Sheila M; Taylor, Barry J; Brown, Deirdre A
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This article is from BMJ Open , volume 4 . Abstract Objectives: As parents of young children are often unaware their child is overweight, screening provides the opportunity to inform parents and provide the impetus for behaviour change. We aimed to determine if parents could recall and understand the information they received about their overweight child after weight screening. Design: Randomised controlled trial of different methods of feedback. Setting: Participants were recruited through...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120339
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Oct 8, 2014
10/14
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Dean-Ben, Xose Luis; Bay, Erwin; Razansky, Daniel
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This article is from Scientific Reports , volume 4 . Abstract The breakthrough capacity of optoacoustics for three-dimensional visualization of dynamic events in real time has been recently showcased. Yet, efficient spectral unmixing for functional imaging of entire volumetric regions is significantly challenged by motion artifacts in concurrent acquisitions at multiple wavelengths. Here, we introduce a method for simultaneous acquisition of multispectral volumetric datasets by introducing a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115207
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Oct 8, 2014
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Di Paolo, Ezequiel Alejandro; Barandiaran, Xabier E.; Beaton, Michael; Buhrmann, Thomas
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This article is from Frontiers in Human Neuroscience , volume 8 . Abstract Learning to perceive is faced with a classical paradox: if understanding is required for perception, how can we learn to perceive something new, something we do not yet understand? According to the sensorimotor approach, perception involves mastery of regular sensorimotor co-variations that depend on the agent and the environment, also known as the “laws” of sensorimotor contingencies (SMCs). In this sense,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115614
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Oct 7, 2014
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Dias, Fabiano Moura; Costa, Susana Ortiz; Pereira de Freitas, Jeter; Pinto, Adriana da Costa Rocha; Vigario, Patricia dos Santos; Mainenti, Miriam Raquel Meira
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This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] A significant increase in the number of oldest old has occurred worldwide. The aim of this study was to characterize the functional capacity of the oldest old residents in a long-stay institution in Rio de Janeiro, Brazil. [Subjects and Methods] All participants were evaluated according to the following metrics: anthropometry, body composition (bioelectrical impedance), handgrip strength, balance (Berg...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135206
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Oct 5, 2014
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Diaz-Perez, Julio A.; Raju, Sharat; Echeverri, Jorge H.
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This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Learning pathology is fundamental for a successful medical practice. In recent years, medical education has undergone a profound transformation toward the development of an integrated curriculum incorporating both basic science and clinical material. Simultaneously, there has been a shift from a magisterial teaching approach to one centered around problem-based learning. Now-a-days, informatics tools are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141419
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Oct 11, 2014
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Diekhof, Esther Kristina; Wittmer, Susanne; Reimers, Luise
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This article is from PLoS ONE , volume 9 . Abstract Parochial altruism, defined as increased ingroup favoritism and heightened outgroup hostility, is a widespread feature of human societies that affects altruistic cooperation and punishment behavior, particularly in intergroup conflicts. Humans tend to protect fellow group members and fight against outsiders, even at substantial costs for themselves. Testosterone modulates responses to competition and social threat, but its exact role in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116333
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Oct 11, 2014
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Dijoux, Laury; Viard, Frederique; Payri, Claude
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This article is from PLoS ONE , volume 9 . Abstract In the past few decades, in the marine realm in particular, the use of molecular tools has led to the discovery of hidden taxonomic diversity, revealing complexes of sister species. A good example is the red algal genus Asparagopsis. The two species (A. armata and A. taxiformis) recognized in this genus have been introduced in many places around the world. Within the nominal species A. taxiformis, previous molecular analyses have uncovered...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116237
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Oct 8, 2014
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Dodev, Tihomir S.; Karagiannis, Panagiotis; Gilbert, Amy E.; Josephs, Debra H.; Bowen, Holly; James, Louisa K.; Bax, Heather J.; Beavil, Rebecca; Pang, Marie O.; Gould, Hannah J.; Karagiannis, Sophia N.; Beavil, Andrew J.
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This article is from Scientific Reports , volume 4 . Abstract Over the last four decades, molecular cloning has evolved tremendously. Efficient products allowing assembly of multiple DNA fragments have become available. However, cost-effective tools for engineering antibodies of different specificities, isotypes and species are still needed for many research and clinical applications in academia. Here, we report a method for one-step assembly of antibody heavy- and light-chain DNAs into a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115235
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Oct 11, 2014
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Dvorkin-Gheva, Anna; Hassell, John A.
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This article is from PLoS ONE , volume 9 . Abstract The molecular classification of human breast tumors has afforded insights into subtype specific biological processes, patient prognosis and response to therapies. However, using current methods roughly one quarter of breast tumors cannot be classified into one or another molecular subtype. To explore the possibility that the unclassifiable samples might comprise one or more novel subtypes we employed a collection of publically available breast...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116208
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Oct 11, 2014
10/14
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Escalera-Zamudio, Marina; Nelson, Martha I.; Cobian Guemes, Ana Georgina; Lopez-Martinez, Irma; Cruz-Ortiz, Natividad; Iguala-Vidales, Miguel; Garcia, Elvia Rodriguez; Barrera-Badillo, Gisela; Diaz-Quinonez, Jose Alberto; Lopez, Susana; Arias, Carlos F.; Isa, Pavel
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This article is from PLoS ONE , volume 9 . Abstract In this work, nineteen influenza A/H3N2 viruses isolated in Mexico between 2003 and 2012 were studied. Our findings show that different human A/H3N2 viral lineages co-circulate within a same season and can also persist locally in between different influenza seasons, increasing the chance for genetic reassortment events. A novel minor cluster was also identified, named here as Korea, that circulated worldwide during 2003. Frequently,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116128
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Oct 9, 2014
10/14
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Falb, Kathryn L; Diaz-Olavarrieta, Claudia; Campos, Paola A; Valades, Jimena; Cardenas, Roosebelinda; Carino, Giselle; Gupta, Jhumka
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This article is from BMC Public Health , volume 14 . Abstract Background: Intimate partner violence (IPV) victimization is a prevalent issue among women residing in Mexico City. Comprehensive and integrated health care provider (HCP) delivered programs in clinic-settings are needed, yet few have been evaluated in Latin America, including Mexico. In addition, there has been minimal attention to interventions among lower income women presenting at settings outside of antenatal care clinics. The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127193
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Oct 11, 2014
10/14
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Ferrara, Maria Antonietta; Dardano, Principia; De Stefano, Luca; Rea, Ilaria; Coppola, Giuseppe; Rendina, Ivo; Congestri, Roberta; Antonucci, Alessandra; De Stefano, Mario; De Tommasi, Edoardo
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This article is from PLoS ONE , volume 9 . Abstract Some natural structures show three-dimensional morphologies on the micro- and nano- scale, characterized by levels of symmetry and complexity well far beyond those fabricated by best technologies available. This is the case of diatoms, unicellular microalgae, whose protoplasm is enclosed in a nanoporous microshell, made of hydrogenated amorphous silica, called frustule. We have studied the optical properties of Arachnoidiscus sp. single valves...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116236
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Oct 11, 2014
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Fischer, Sebastian; Wiemer, Anita; Diedrich, Laura; Moock, Jorn; Rossler, Wulf
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This article is from PLoS ONE , volume 9 . Abstract We suggest that interactions with strangers at work influence the likelihood of depressive disorders, as they serve as an environmental stressor, which are a necessary condition for the onset of depression according to diathesis-stress models of depression. We examined a large dataset (N = 76,563 in K = 196 occupations) from the German pension insurance program and the Occupational Information Network dataset on occupational...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116212
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Oct 10, 2014
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Fukutani, Kiyoshi F; Figueiredo, Virginia; Celes, Fabiana S; Cristal, Juqueline R; Barral, Aldina; Barral-Netto, Manoel; de Oliveira, Camila I
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This article is from BMC Infectious Diseases , volume 14 . Abstract Background: Visceral Leishmaniasis is endemic to Brazil, where it is caused by Leishmania infantum (syn. Leishmania chagasi). Following parasite inoculation, individuals may experience asymptomatic infection, raising the possibility of parasite transmission through the transfusion of contaminated blood products. In the present work, we evaluated the prevalence of asymptomatic Leishmania infection among blood donors in Salvador,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122787
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Oct 10, 2014
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Garcia-Diaz, Lutgardo; de Agustin, Juan Carlos; Ontanilla, Antonio; Marenco, Maria Luisa; Pavon, Antonio; Losada, Antonio; Antinolo, Guillermo
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This article is from BMC Pregnancy and Childbirth , volume 14 . Abstract Background: Indications for the ex utero intrapartum therapy (EXIT) procedure have evolved and nowadays in addition to secure the airway, obtain vascular access, administer surfactant and other resuscitation medications, EXIT is used to resect cervical or thoracic masses, for extracorporeal membrane circulation (ECMO) cannulation, as well as to rescue maximum intra-thoracic space for ventilation of the remaining functional...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124143
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Oct 8, 2014
10/14
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Gunnoo, Smita B.; Finney, Helene M.; Baker, Terry S.; Lawson, Alastair D.; Anthony, Daniel C.; Davis, Benjamin G.
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This article is from Nature Communications , volume 5 . Abstract The ability to conditionally direct antibodies is a potentially powerful application for Synthetic Biology in Medicine. Here we show that control of antibody binding through site-specific, chemical phosphorylation of a recognition domain creates a ‘gated’ antibody (Ab). This displays a crude Boolean logic where binding is induced in an enzyme-AND-antigen dependent manner. This ‘AND-Ab’ is therefore active only in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124856
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Oct 4, 2014
10/14
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Gupta, Parikshaa; Dey, Pranab
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This article is from CytoJournal , volume 11 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141426
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Oct 11, 2014
10/14
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Hessamfar, Mojgan; Colin, Celine; Bruyand, Mathias; Decoin, Madeleine; Bonnet, Fabrice; Mercie, Patrick; Neau, Didier; Cazanave, Charles; Pellegrin, Jean-Luc; Dabis, Francois; Morlat, Philippe; Chene, Genevieve
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This article is from PLoS ONE , volume 9 . Abstract Objective: To describe trends and determinants of severe morbidity in HIV-infected women and men. Design: A French prospective cohort of HIV-infected patients of both sexes and all transmission categories. Methods: We used hospital admission data from January 2000 to December 2008. A severe morbid event (SME) was defined as a clinical event requiring hospitalization for ≥48 h, several events could be reported during hospitalization. Yearly...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116171
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Oct 10, 2014
10/14
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Hodzic, Adnan; Latrofa, Maria Stefania; Annoscia, Giada; Alic, Amer; Beck, Relja; Lia, Riccardo Paolo; Dantas-Torres, Filipe; Otranto, Domenico
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This article is from Parasites & Vectors , volume 7 . Abstract Background: Thelazia callipaeda (Spirurida, Thelaziidae), also known as “oriental eyeworm”, is a small nematode parasite that lives in the conjunctival sac of domestic and wild carnivores, rabbits and even humans, causing mild (e.g., conjunctivitis, epiphora, and ocular discharge) to severe (e.g., keratitis, and corneal ulcers) ocular disease. This study reports, for the first time, the occurrence of T. callipaeda infection...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124150
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Oct 7, 2014
10/14
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Jiang, Ke; Li, Yingchun; Zhu, Qiumin; Xu, Jiansheng; Wang, Yupeng; Deng, Wuguo; Liu, Quentin; Zhang, Guirong; Meng, Songshu
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This article is from BMC Cancer , volume 14 . Abstract Background: Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells. Methods: The effect of NDV/FMW infection on autophagy machinery in A549...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141091
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Oct 5, 2014
10/14
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Karekezi, C.; Egu, K.; Djoubairou, B. O.; Boutarbouch, M.; Ouahabi, A. El
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This article is from Surgical Neurology International , volume 5 . Abstract Background:: Schwannomas are tumors of peripheral nerves that develop from the nerve sheath. Foraminal schwannomas are rare and account for 1-5% of all spinal schwannomas. The lumbosacral root schwannoma is a rare cause of sciatica and may raise confusion in diagnosis with late discovery of the tumor. Case Description:: We report the case of a patient 30 years of age with chronic left sciatica in whom lumbosacral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138822
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Oct 7, 2014
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Khan, Samsuddin; Das, Mrinalini; Andries, Aristomo; Deshpande, Alaka; Mansoor, Homa; Saranchuk, Peter; Isaakidis, Petros
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This article is from Global Health Action , volume 7 . Abstract Background: There are limited data on the failure of second-line antiretroviral therapy (ART) and the use of third-line ART in people living with HIV in resource-limited settings. Since 2011, the Médecins Sans Frontières (MSF) HIV/tuberculosis programme in Mumbai, India, has been providing third-line ART to patients in care. Objective: To describe the experiences and programmatic challenges during management of suspected...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119292
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Oct 8, 2014
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Kim, Maria H; Mazenga, Alick C; Devandra, Akash; Ahmed, Saeed; Kazembe, Peter N; Yu, Xiaoying; Nguyen, Chi; Sharp, Carla
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This article is from Journal of the International AIDS Society , volume 17 . Abstract Introduction: There is a remarkable dearth of evidence on mental illness in adolescents living with HIV/AIDS, particularly in the African setting. Furthermore, there are few studies in sub-Saharan Africa validating the psychometric properties of diagnostic and screening tools for depression amongst adolescents. The primary aim of this cross-sectional study was to estimate the prevalence of depression amongst a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119288
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Oct 6, 2014
10/14
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Kim, Namsuk; Acampora, Dario; Dingli, Florent; Loew, Damarys; Simeone, Antonio; Prochiantz, Alain; A. Di Nardo, Ariel
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This article is from F1000Research , volume 3 . Abstract Plasticity in the visual cerebral cortex is regulated by the internalization of Otx2 homeoprotein into parvalbumin neurons in cortical layers II/III and IV. However the Otx2 locus is not active in these neurons and the protein is imported from external sources, including the choroid plexus. Because Otx1 and Otx2 may have redundant functions, we wanted to verify if part of the staining in parvalbumin neurons corresponds to Otx1 transported...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133762
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Oct 11, 2014
10/14
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Kleemann, Britta; Loos, Benjamin; Scriba, Thomas J.; Lang, Dirk; Davids, Lester M.
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This article is from PLoS ONE , volume 9 . Abstract Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising photosensitizer in the context of clinical photodynamic therapy due to its excellent photosensitizing properties and tumoritropic characteristics. Hypericin-PDT induced cytotoxicity elicits tumor cell death by various mechanisms including apoptosis, necrosis and autophagy-related cell death. However, limited reports on the efficacy of this photomedicine for the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116257
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120
Oct 9, 2014
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Lindenblatt, Nicole; El-Rabadi, Karem; Helbich, Thomas H; Czembirek, Heinrich; Deutinger, Maria; Benditte-Klepetko, Heike
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This article is from International Journal of Women's Health , volume 6 . Abstract Background: Silicone gel breast implants may silently rupture without detection. This has been the main reason for magnetic resonance imaging (MRI) of the augmented or reconstructed breast. The aim of the present study was to investigate the accuracy of MRI for implant rupture. Methods: Fifty consecutive patients with 85 silicone gel implants were included in the study. The mean age of the patients was 51 (range...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124066
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Oct 6, 2014
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Lozano, Reymundo; Hagerman, Randi J; Duyzend, Michael; Budimirovic, Dejan B; Eichler, Evan E; Tassone, Flora
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This article is from Journal of Neurodevelopmental Disorders , volume 6 . Abstract Background: The FMR1 premutation is defined as having 55 to 200 CGG repeats in the 5′ untranslated region of the fragile X mental retardation 1 gene (FMR1). The clinical involvement has been well characterized for fragile X-associated tremor/ataxia syndrome (FXTAS) and fragile X-associated primary ovarian insufficiency (FXPOI). The behavior/psychiatric and other neurological manifestations remain to be...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147387
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Oct 8, 2014
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Mailhot, Tanya; Cossette, Sylvie; Bourbonnais, Anne; Cote, Jose; Denault, Andre; Cote, Marie-Claude; Lamarche, Yoan; Guertin, Marie-Claude
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This article is from Trials , volume 15 . Abstract Background: Despite the use of evidence-based preventive measures, delirium affects about 40% of patients following cardiac surgery with the potential for serious clinical complications and anxiety for caregivers. There is some evidence that family involvement as a core component of delirium management may be beneficial since familiarity helps patients stay in contact with reality, however, this merits further investigation. There is also...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133622
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Oct 11, 2014
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McMahon, George; Taylor, Amy E.; Davey Smith, George; Munafo, Marcus R.
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This article is from PLoS ONE , volume 9 . Abstract Two genetic loci, one in the cytochrome P450 1A1 (CYP1A1) and 1A2 (CYP1A2) gene region (rs2472297) and one near the aryl-hydrocarbon receptor (AHR) gene (rs6968865), have been associated with habitual caffeine consumption. We sought to establish whether a more refined and comprehensive assessment of caffeine consumption would provide stronger evidence of association, and whether a combined allelic score comprising these two variants would...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116211
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Oct 8, 2014
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McRae, Kathryn M; McEwan, John C; Dodds, Ken G; Gemmell, Neil J
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This article is from BMC Genomics , volume 15 . Abstract Background: Gastrointestinal nematodes are one of the most serious causes of disease in domestic ruminants worldwide. There is considerable variation in resistance to gastrointestinal nematodes within and between sheep breeds, which appears to be due to underlying genetic diversity. Through selection of resistant animals, rapid genetic progress has been demonstrated in both research and commercial flocks. Recent advances in genome...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124167
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Oct 7, 2014
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Neto, Hugo Pasini; Grecco, Luanda Andre Collange; Duarte, Natalia Almeida Carvalho; Christovao, Thaluanna Calil Lourenco; Franco de Oliveira, Luis Vicente; Dumont, Arislander Jonathan Lopes; Galli, Manuela; Oliveira, Claudia Santos
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This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] Improved gait efficiency is one of the goals of therapy for children with cerebral palsy (CP). Postural insoles can allow more efficient gait by improving biomechanical alignment. The aim of the present study was to assess the effect of postural insoles on gait performance of children with CP classified as levels I or II of the Gross Motor Function Classification System (GMFCS). [Subjects and Methods] the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135184
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Oct 3, 2014
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Nombela, Cristina; Rowe, James B.; Winder-Rhodes, Sophie E.; Hampshire, Adam; Owen, Adrian M.; Breen, David P.; Duncan, Gordon W.; Khoo, Tien K.; Yarnall, Alison J.; Firbank, Michael J.; Chinnery, Patrick F.; Robbins, Trevor W.; O'Brien, John T.; Brooks, David J.; Burn, David J.; Barker, Roger A.
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This article is from Brain , volume 137 . Abstract See Dujardin (doi:10.1093/brain/awu218) for a scientific commentary on this article. Nombela et al. present data from the ICICLE-PD study of cognition in newly diagnosed Parkinson’s disease. Consistent with the ‘Dual Syndrome’ hypothesis, impairments in executive function reflect a frontal dopaminergic syndrome modulated by COMT genotype, while visuospatial and memory deficits reflect disruption of temporo-parietal systems modulated by...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163033
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Oct 5, 2014
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Obaid, Sami; Li, Shu; Denis, Daniel; Weil, Alexander G.; Bojanowski, Michel W.
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This article is from Surgical Neurology International , volume 5 . Abstract Background:: Cavernous angiomas (CAs) of cranial nerves are rare, and their occurrence on the third cranial nerve is particularly rare. Surgical management of such CAs involving the third nerve is controversial. We describe a case of a symptomatic CA of the oculomotor nerve and review the literature in order to ascertain the relevance of surgical intervention. Case Description:: A 71-year-old male patient presented with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138817
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Oct 10, 2014
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Piegeler, Tobias; Dreessen, Pamela; Graber, Sereina M; Haile, Sarah R; Schmid, Daniel Max; Beck-Schimmer, Beatrice
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This article is from BMC Anesthesiology , volume 14 . Abstract Background: Robotic-assisted laparoscopic prostatectomy (RALP) gained much popularity during the last decade. Although the influence of intraoperative fluid management on patients’ outcome has been largely discussed in general, its impact on perioperative complications and length of hospitalization in patients undergoing RALP has not been examined so far. We hypothesized that a more restrictive fluid management might lead to a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123305
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Oct 11, 2014
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Pisano, Fabio; Heine, Wiebke; Rosenheinrich, Maik; Schweer, Janina; Nuss, Aaron M.; Dersch, Petra
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This article is from PLoS ONE , volume 9 . Abstract The two-component regulatory system PhoP/PhoQ has been shown to (i) control expression of virulence-associated traits, (ii) confer survival and growth within macrophages and (iii) play a role in Yersinia infections. However, the influence of PhoP on virulence varied greatly between different murine models of infection and its role in natural oral infections with frequently used representative isolates of Y. pseudotuberculosis was unknown. To...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116203
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Oct 11, 2014
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Rakotoarinivo, Mijoro; Dransfield, John; Bachman, Steven P.; Moat, Justin; Baker, William J.
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This article is from PLoS ONE , volume 9 . Abstract The establishment of baseline IUCN Red List assessments for plants is a crucial step in conservation planning. Nowhere is this more important than in biodiversity hotspots that are subject to significant anthropogenic pressures, such as Madagascar. Here, all Madagascar palm species are assessed using the IUCN Red List categories and criteria, version 3.1. Our results indicate that 83% of the 192 endemic species are threatened, nearly four...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116232
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Oct 11, 2014
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Robison, Bruce; Seibel, Brad; Drazen, Jeffrey
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This article is from PLoS ONE , volume 9 . Abstract Octopuses typically have a single reproductive period and then they die (semelparity). Once a clutch of fertilized eggs has been produced, the female protects and tends them until they hatch. In most shallow-water species this period of parental care can last from 1 to 3 months, but very little is known about the brooding of deep-living species. In the cold, dark waters of the deep ocean, metabolic processes are often slower than their...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116195
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Roozendaal, Ramon; Tolboom, Jeroen; Roos, Anna; Riahi, Sarra; Theeuwsen, Jessica; Bujny, Miriam V.; Klaren, Vincent; Korse, Hans J. W. M.; Dekking, Liesbeth; Grootenhuis, Arijan; Weverling, Gerrit Jan; Koudstaal, Wouter; Goudsmit, Jaap; Radosevic, Katarina
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This article is from PLoS ONE , volume 9 . Abstract Current influenza vaccines are believed to confer protection against a narrow range of virus strains. The identification of broadly influenza neutralizing antibodies (bnAbs) has triggered efforts to develop vaccines providing ‘universal’ protection against influenza. Several bnAbs were isolated from humans recently vaccinated with conventional influenza vaccines, suggesting that such vaccines could, in principle, be broadly protective....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116209
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Oct 7, 2014
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Sodjinou, Roger; Bosu, William K.; Fanou, Nadia; Deart, Lucie; Kupka, Roland; Tchibindat, Felicite; Baker, Shawn
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This article is from Global Health Action , volume 7 . Abstract Background: Health professionals play a key role in the delivery of nutrition interventions. Improving the quality of nutrition training in health professional schools is vital for building the necessary human resource capacity to implement effective interventions for reducing malnutrition in West Africa. This study was undertaken to assess the current status of nutrition training in medical, nursing and midwifery schools in West...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119290
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Oct 11, 2014
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Solca, Manuela da Silva; Bastos, Leila Andrade; Guedes, Carlos Eduardo Sampaio; Bordoni, Marcelo; Borja, Lairton Souza; Larangeira, Daniela Farias; da Silva Estrela Tuy, Petala Gardenia; Amorim, Leila Denise Alves Ferreira; Nascimento, Eliane Gomes; de Sa Oliveira, Geraldo Gileno; dos-Santos, Washington Luis Conrado; Fraga, Deborah Bittencourt Mothe; Veras, Patricia Sampaio Tavares
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This article is from PLoS ONE , volume 9 . Abstract Host tissues affected by Leishmania infantum have differing degrees of parasitism. Previously, the use of different biological tissues to detect L. infantum DNA in dogs has provided variable results. The present study was conducted to evaluate the accuracy of molecular diagnostic testing (qPCR) in dogs from an endemic area for canine visceral leishmaniasis (CVL) by determining which tissue type provided the highest rate of parasite DNA...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116254
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Oct 8, 2014
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Soysa, Preethi; De Silva, Irushi Shamalika; Wijayabandara, Jayantha
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This article is from BMC Complementary and Alternative Medicine , volume 14 . Abstract Background: Flueggea leucopyrus Willd is a shrub grown in many parts of the dry zones in Sri Lanka. The leaves of F. leucopyrus has been used for treating cancer in the traditional system of medicine in Sri Lanka. Hence, this study was performed to analyze the antioxidant and antiproliferative properties of the aqueous extract of the leaves of F. leucopyrus on HEp-2 cells. Method: The aqueous extract of F....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129101
