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Oct 7, 2014
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Akizuki, Kazunori; Yazaki, Syouichirou; Echizenya, Yuki; Ohashi, Yukari
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This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] The purpose of this study was to clarify the validity of salivary α-amylase as a method of quickly estimating anaerobic threshold and to establish the relationship between salivary α-amylase and double-product breakpoint in order to create a way to adjust exercise intensity to a safe and effective range. [Subjects and Methods] Eleven healthy young adults performed an incremental exercise test using a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135198
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Oct 6, 2014
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Barrios, Vivencio; Escobar, Carlos
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This article is from Integrated Blood Pressure Control , volume 7 . Abstract Combined therapy is required in the majority of patients with hypertension to achieve blood pressure (BP) targets. Although different antihypertensive drugs can be combined, not all combinations are equally effective and safe. In this context, the combination of a renin angiotensin system inhibitor with a diuretic, usually a thiazide, particularly hydrochlorothiazide (HCTZ) or thiazide-like diuretics, such as...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142573
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Oct 8, 2014
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Becker, C.; Wyss, P.; Eisenhauer, D.; Probst, J.; Preidel, V.; Hammerschmidt, M.; Burger, S.
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This article is from Scientific Reports , volume 4 . Abstract Crystalline silicon photonic crystal slabs are widely used in various photonics applications. So far, the commercial success of such structures is still limited owing to the lack of cost-effective fabrication processes enabling large nanopatterned areas (≫ 1 cm2). We present a simple method for producing crystalline silicon nanohole arrays of up to 5 × 5 cm2 size with lattice pitches between 600 and 1000 nm on glass and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115234
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Oct 11, 2014
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Blaho, Miklos; Herczeg, Tamas; Kriska, Gyorgy; Egri, Adam; Szaz, Denes; Farkas, Alexandra; Tarjanyi, Nikolett; Czinke, Laszlo; Barta, Andras; Horvath, Gabor
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This article is from PLoS ONE , volume 9 . Abstract The horizontally polarizing surface parts of shiny black cars (the reflection-polarization characteristics of which are similar to those of water surfaces) attract water-leaving polarotactic insects. Thus, shiny black cars are typical sources of polarized light pollution endangering water-leaving insects. A new fashion fad is to make car-bodies matt black or grey. Since rough (matt) surfaces depolarize the reflected light, one of the ways of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116178
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Oct 7, 2014
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Couch, Robert B; Bayas, Jose M; Caso, Covadonga; Mbawuike, Innocent Nnadi; Lopez, Concepcion Nunez; Claeys, Carine; El Idrissi, Mohamed; Herve, Caroline; Laupeze, Beatrice; Oostvogels, Lidia; Moris, Philippe
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This article is from BMC Infectious Diseases , volume 14 . Abstract Background: The effectiveness of trivalent influenza vaccines may be reduced in older versus younger adults because of age-related immunosenescence. The use of an adjuvant in such a vaccine is one strategy that may combat immunosenescence, potentially by bolstering T-cell mediated responses. Methods: This observer-blind study, conducted in the United States (US) and Spain during the 2008–2009 influenza season, evaluated the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138369
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Oct 5, 2014
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Diaz-Perez, Julio A.; Raju, Sharat; Echeverri, Jorge H.
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This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Learning pathology is fundamental for a successful medical practice. In recent years, medical education has undergone a profound transformation toward the development of an integrated curriculum incorporating both basic science and clinical material. Simultaneously, there has been a shift from a magisterial teaching approach to one centered around problem-based learning. Now-a-days, informatics tools are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141419
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Oct 11, 2014
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Eduardo, Eduard; Lamb, Matthew R.; Kandula, Sasi; Howard, Andrea; Mugisha, Veronicah; Kimanga, Davies; Kilama, Bonita; El-Sadr, Wafaa; Elul, Batya
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This article is from PLoS ONE , volume 9 . Abstract Background: Limited information exists on adults ≥50 years receiving HIV care in sub-Saharan Africa. Methodology: Using routinely-collected longitudinal patient-level data among 391,111 adults ≥15 years enrolling in HIV care from January 2005–December 2010 and 184,689 initiating ART, we compared characteristics and outcomes between older (≥50 years) and younger adults at 199 clinics in Kenya, Mozambique, Rwanda, and Tanzania. We...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116238
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Oct 11, 2014
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Egekwu, Noble; Sonenshine, Daniel E.; Bissinger, Brooke W.; Roe, R. Michael
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This article is from PLoS ONE , volume 9 . Abstract Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods. However, for molecular processes, it was more successful for the Illumina samples than for 454 samples. Functional assignments of transcripts predicting neuropeptides, neuropeptide receptors, neurotransmitter receptors and other...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116169
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Oct 11, 2014
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Escalera-Zamudio, Marina; Nelson, Martha I.; Cobian Guemes, Ana Georgina; Lopez-Martinez, Irma; Cruz-Ortiz, Natividad; Iguala-Vidales, Miguel; Garcia, Elvia Rodriguez; Barrera-Badillo, Gisela; Diaz-Quinonez, Jose Alberto; Lopez, Susana; Arias, Carlos F.; Isa, Pavel
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This article is from PLoS ONE , volume 9 . Abstract In this work, nineteen influenza A/H3N2 viruses isolated in Mexico between 2003 and 2012 were studied. Our findings show that different human A/H3N2 viral lineages co-circulate within a same season and can also persist locally in between different influenza seasons, increasing the chance for genetic reassortment events. A novel minor cluster was also identified, named here as Korea, that circulated worldwide during 2003. Frequently,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116128
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Oct 10, 2014
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Fazel, Ramin; Zarei, Najmeh; Ghaemi, Nasser; Namvaran, Mohammad Mehdi; Enayati, Somayeh; Mirabzadeh Ardakani, Esmat; Azizi, Mohammad; Khalaj, Vahid
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This article is from SpringerPlus , volume 3 . Abstract Urate oxidase is an important enzyme with therapeutic and diagnostic applications. Rasburicase is a recombinant urate oxidase enzyme approved by FDA to use in the treatment of hyperuricemia conditions. Various hosts such as Saccharomyces cerevisiae, Hansenula polymorpha and Escherichia coli have been used to express the enzyme. Today, Pichia pastoris is considered as an important host for heterologous protein expression since it has...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124111
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Oct 8, 2014
10/14
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Gillies, Katie; Elwyn, Glyn; Cook, Jonathan
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This article is from Trials , volume 15 . Abstract Background: Informed consent of trial participants is both an ethical and a legal requirement. When facing a decision about trial participation, potential participants are provided with information about the trial and have the opportunity to have any questions answered before their degree of ‘informed-ness’ is assessed, usually subjectively, and before they are asked to sign a consent form. Currently, standardised methods for assessing...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4131044
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Oct 10, 2014
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Hafstrom, Ingiald; Engvall, Inga-Lill; Ronnelid, Johan; Boonen, Annelies; van der Heijde, Desiree; Svensson, Bjorn
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This article is from BMJ Open , volume 4 . Abstract Objective: To analyse if predictors of radiographic progression differ between patients treated with or without prednisolone in early rheumatoid arthritis (RA). Radiographs of hands and feet were assessed using the modified Sharp/van der Heijde score and radiographic progression was defined as an increase in the total Sharp score above 5.8 (the smallest detectable change). Design: Prospective, randomised study of patients with early RA....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120364
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Oct 11, 2014
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Harper, Diane M.; Else, Britney M.; Bartley, Mitchell J.; Arey, Anne M.; Barnett, Angela L.; Rosemergey, Beth E.; Paynter, Christopher A.; Verdenius, Inge; Harper, Sean M.; Harris, George D.; Groner, Jennifer A.; Malnar, Gerard J.; Wall, Jeffrey; Bonham, Aaron J.
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This article is from PLoS ONE , volume 9 . Abstract Objectives: Obesity adversely inhibits antibody response to vaccination. Three doses of HPV4 may or may not provide adequate long term protection against HPV 16/18 in obese females. The aim of this study was to determine whether adherence to HPV4 vaccination in a safety net population was reduced with increasing body mass index (BMI). Methods: We designed a historical prospective study evaluating the number and dates of HPV4 dosing that...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116139
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Oct 8, 2014
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Hsu, Clarissa; Sherman, Karen J; Eaves, Emery R; Turner, Judith A; Cherkin, Daniel C; Cromp, DeAnn; Schafer, Lisa; Ritenbaugh, Cheryl
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This article is from BMC Complementary and Alternative Medicine , volume 14 . Abstract Background: Positive patient expectations are often believed to be associated with greater benefits from complementary and alternative medicine (CAM) treatments. However, clinical studies of CAM treatments for chronic pain have not consistently supported this assumption, possibly because of differences in definitions and measures of expectations. The goal of this qualitative paper is to provide new...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129105
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Oct 8, 2014
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Iwelunmor, Juliet; Ezeanolue, Echezona E; Airhihenbuwa, Collins O; Obiefune, Michael C; Ezeanolue, Chinenye O; Ogedegbe, Gbenga G
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This article is from BMC Public Health , volume 14 . Abstract Background: Currently, Nigeria alone accounts for 30% of the burden of mother-to-child transmission of HIV. This review explores the socio-cultural factors influencing prevention of mother-to-child transmission of HIV (PMTCT) service uptake in Nigeria. Methods: Using the PEN-3 cultural model as a guide, we searched electronic databases and conducted a synthesis of empirical studies conducted from 2001 to 2013 that reported the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133635
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Oct 5, 2014
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Karekezi, C.; Egu, K.; Djoubairou, B. O.; Boutarbouch, M.; Ouahabi, A. El
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This article is from Surgical Neurology International , volume 5 . Abstract Background:: Schwannomas are tumors of peripheral nerves that develop from the nerve sheath. Foraminal schwannomas are rare and account for 1-5% of all spinal schwannomas. The lumbosacral root schwannoma is a rare cause of sciatica and may raise confusion in diagnosis with late discovery of the tumor. Case Description:: We report the case of a patient 30 years of age with chronic left sciatica in whom lumbosacral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138822
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Oct 9, 2014
10/14
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Lahat, Adi; Neuman, Sandra; Eliakim, Rami; Ben-Horin, Shomron
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This article is from Clinical and Experimental Gastroenterology , volume 7 . Abstract Background: Chronic inflammatory bowel disease (IBD) causes significant distress for patients and their families. Data assessing the need of these patients for support and sharing with their partners are scarce. The aim of this study was to assess patients’ views regarding sharing of information with their partners. Methods: Ambulatory IBD patients treated at the Chaim Sheba Medical Center between January...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122224
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Oct 9, 2014
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Lindenblatt, Nicole; El-Rabadi, Karem; Helbich, Thomas H; Czembirek, Heinrich; Deutinger, Maria; Benditte-Klepetko, Heike
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This article is from International Journal of Women's Health , volume 6 . Abstract Background: Silicone gel breast implants may silently rupture without detection. This has been the main reason for magnetic resonance imaging (MRI) of the augmented or reconstructed breast. The aim of the present study was to investigate the accuracy of MRI for implant rupture. Methods: Fifty consecutive patients with 85 silicone gel implants were included in the study. The mean age of the patients was 51 (range...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124066
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Oct 6, 2014
10/14
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Lozano, Reymundo; Hagerman, Randi J; Duyzend, Michael; Budimirovic, Dejan B; Eichler, Evan E; Tassone, Flora
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This article is from Journal of Neurodevelopmental Disorders , volume 6 . Abstract Background: The FMR1 premutation is defined as having 55 to 200 CGG repeats in the 5′ untranslated region of the fragile X mental retardation 1 gene (FMR1). The clinical involvement has been well characterized for fragile X-associated tremor/ataxia syndrome (FXTAS) and fragile X-associated primary ovarian insufficiency (FXPOI). The behavior/psychiatric and other neurological manifestations remain to be...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147387
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Oct 11, 2014
10/14
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Mohammadrezaei, Mohammad; Toghyani, Majid; Gheisari, Abbasali; Toghyani, Mehdi; Eghbalsaied, Shahin
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This article is from PLoS ONE , volume 9 . Abstract The aim of this study was to investigate the effects of Fadrozole hydrochloride and recombinant human insulin-like growth factor I (rhIGF-I) on female-to-male sex reversal, hatching traits, and body weight of broiler chickens. On the third day of incubation, fertile eggs were randomly assigned to five experimental groups comprising (i) Fadrozole (0.1 mg/egg), (ii) rhIGF-I (100 ng/egg), (iii) Fadrozole (0.1 mg/egg) + rhIGF-I (100 ng/egg), (iv)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116201
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Oct 5, 2014
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Nelson, Heidi D.; Weerasinghe, Roshanthi; Martel, Maritza; Bifulco, Carlo; Assur, Ted; Elmore, Joann G.; Weaver, Donald L.
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This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Health care systems rely on electronic patient data, yet access to breast tissue pathology results continues to depend on interpreting dictated free-text reports. Objective:: The objective was to develop a method to electronically search and categorize pathologic diagnoses of patients’ breast tissue specimens from dictated free-text pathology reports in a large health system for multiple users including...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141424
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Oct 11, 2014
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Normark, Johan; Nelson, Maria; Engstrom, Patrik; Andersson, Marie; Bjork, Rafael; Moritz, Thomas; Fahlgren, Anna; Bergstrom, Sven
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This article is from PLoS ONE , volume 9 . Abstract In the Plasmodium infected host, a balance between pro- and anti-inflammatory responses is required to clear the parasites without inducing major host pathology. Clinical reports suggest that bacterial infection in conjunction with malaria aggravates disease and raises both mortality and morbidity in these patients. In this study, we investigated the immune responses in BALB/c mice, co-infected with Plasmodium berghei NK65 parasites and the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116174
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Oct 3, 2014
10/14
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Peffers, Mandy J.; Thorpe, Chavaunne T.; Collins, John A.; Eong, Robin; Wei, Timothy K. J.; Screen, Hazel R. C.; Clegg, Peter D.
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This article is from The Journal of Biological Chemistry , volume 289 . Abstract Background: Alterations in tendon matrix composition with aging and injury are poorly understood.Results: Aging and injury resulted in distinct protein profiles, with age-specific peptide fragmentation in injury.Conclusion: Identification of protein cleavages associated with aging and injury suggest impaired maintenance and repair in aged tendon.Significance: Novel peptide fragments identified are potential...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162187
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Oct 8, 2014
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Raza, Zamaan; Errea, Ion; Oganov, Artem R.; Saitta, A. Marco
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This article is from Scientific Reports , volume 4 . Abstract State of the art variable composition structure prediction based on density functional theory demonstrates that two new stoichiometries of PN, PN3 and PN2, become viable at high pressure. PN3 has a skutterudite-like Immm structure and is metastable with positive phonon frequencies at pressures between 10 and 100 GPa. PN3 is metallic and is the first reported nitrogen-based skutterudite. Its metallicity arises from nitrogen p-states...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115206
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Oct 11, 2014
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Song, Yajing; Giske, Christian G.; Gille-Johnson, Patrik; Emanuelsson, Olof; Lundeberg, Joakim; Gyarmati, Peter
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This article is from PLoS ONE , volume 9 . Abstract Sepsis is a severe medical condition characterized by a systemic inflammatory response of the body caused by pathogenic microorganisms in the bloodstream. Blood or plasma is typically used for diagnosis, both containing large amount of human DNA, greatly exceeding the DNA of microbial origin. In order to enrich bacterial DNA, we applied the C0t effect to reduce human DNA background: a model system was set up with human and Escherichia coli (E....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116218
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Oct 11, 2014
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Thevenard, Jessica; Verzeaux, Laurie; Devy, Jerome; Etique, Nicolas; Jeanne, Albin; Schneider, Christophe; Hachet, Cathy; Ferracci, Geraldine; David, Marion; Martiny, Laurent; Charpentier, Emmanuelle; Khrestchatisky, Michel; Rivera, Santiago; Dedieu, Stephane; Emonard, Herve
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This article is from PLoS ONE , volume 9 . Abstract Tissue inhibitor of metalloproteinases-1 (TIMP-1) regulates the extracellular matrix turnover by inhibiting the proteolytic activity of matrix metalloproteinases (MMPs). TIMP-1 also displays MMP-independent activities that influence the behavior of various cell types including neuronal plasticity, but the underlying molecular mechanisms remain mostly unknown. The trans-membrane receptor low-density lipoprotein receptor-related protein-1...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116228
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Oct 4, 2014
10/14
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Uludokumaci, Atay; Canberk, Sule; Elcin, Bilge Baskir; Uygun, Nesrin; Cakalir, Canser; Canberk, Mehmet
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This article is from CytoJournal , volume 11 . Abstract None
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141412
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Oct 11, 2014
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Vallverdu, Josep; Saladie, Palmira; Rosas, Antonio; Huguet, Rosa; Caceres, Isabel; Mosquera, Marina; Garcia-Tabernero, Antonio; Estalrrich, Almudena; Lozano-Fernandez, Ivan; Pineda-Alcala, Antonio; Carrancho, Angel; Villalain, Juan Jose; Bourles, Didier; Braucher, Regis; Lebatard, Anne; Vilalta, Jaume; Esteban-Nadal, Montserrat; Bennasar, Maria Lluc; Bastir, Marcus; Lopez-Polin, Lucia; Olle, Andreu; Verges, Josep Maria; Ros-Montoya, Sergio; Martinez-Navarro, Bienvenido; Garcia, Ana; Martinell,...
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This article is from PLoS ONE , volume 9 . Abstract The first arrivals of hominin populations into Eurasia during the Early Pleistocene are currently considered to have occurred as short and poorly dated biological dispersions. Questions as to the tempo and mode of these early prehistoric settlements have given rise to debates concerning the taxonomic significance of the lithic assemblages, as trace fossils, and the geographical distribution of the technological traditions found in the Lower...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116235
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Oct 14, 2014
10/14
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Wanda, Franck; Nkemenang, Patrick; Ehounou, Genevieve; Tchaton, Marie; Comte, Eric; Toutous Trellu, Laurence; Masouye, Isabelle; Christinet, Vanessa; O'Brien, Daniel P
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This article is from BMC Infectious Diseases , volume 14 . Abstract Background: In West and Central Africa Buruli ulcer (BU) and HIV co-infection is increasingly recognised and management of these two diseases combined is an emerging challenge for which there is little published information. In this case we present a severe paradoxical reaction occurring after commencing antibiotic treatment for BU combined with antiretroviral therapy for HIV, and describe its clinical features and management....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122778
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Oct 8, 2014
10/14
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Wilson, C. Brad; McLaughlin, Leslie D.; Ebenezer, Philip J.; Nair, Anand R.; Dange, Rahul; Harre, Joseph G.; Shaak, Thomas L.; Diamond, David M.; Francis, Joseph
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This article is from Frontiers in Behavioral Neuroscience , volume 8 . Abstract Serotonin (5-HT), norepinephrine (NE), and other neurotransmitters are modulated in post-traumatic stress disorder (PTSD). In addition, pro-inflammatory cytokines (PIC) are elevated during the progression of the disorder. Currently, the only approved pharmacologic treatments for PTSD are the selective-serotonin reuptake inhibitors (SSRI) sertraline and paroxetine, but their efficacy in treating PTSD is marginal at...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115632
