73
73
Oct 14, 2014
10/14
Oct 14, 2014
by
Wanda, Franck; Nkemenang, Patrick; Ehounou, Genevieve; Tchaton, Marie; Comte, Eric; Toutous Trellu, Laurence; Masouye, Isabelle; Christinet, Vanessa; O'Brien, Daniel P
texts
eye 73
favorite 0
comment 0
This article is from BMC Infectious Diseases , volume 14 . Abstract Background: In West and Central Africa Buruli ulcer (BU) and HIV co-infection is increasingly recognised and management of these two diseases combined is an emerging challenge for which there is little published information. In this case we present a severe paradoxical reaction occurring after commencing antibiotic treatment for BU combined with antiretroviral therapy for HIV, and describe its clinical features and management....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122778
57
57
Oct 14, 2014
10/14
Oct 14, 2014
by
Horimoto, Yoshiya; Arakawa, Atsushi; Tanabe, Masahiko; Sonoue, Hiroshi; Igari, Fumie; Senuma, Koji; Tokuda, Emi; Shimizu, Hideo; Kosaka, Taijiro; Saito, Mitsue
texts
eye 57
favorite 0
comment 0
This article is from BMC Cancer , volume 14 . Abstract Background: Patients with luminal HER2-negative tumours have a favourable prognosis. However, there is a subpopulation in which poorer outcomes are obtained with endocrine therapy alone. This subpopulation is considered to benefit from chemotherapy. However, the significance of chemotherapy for those with luminal tumours has decreased due to recent changes in treatment strategies. Thus, it is often difficult to determine whether we should...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124146
65
65
Oct 13, 2014
10/14
Oct 13, 2014
by
Wu, Zehong; Liu, Dong; Proksch, Peter; Guo, Peng; Lin, Wenhan
texts
eye 65
favorite 0
comment 0
This article is from Marine Drugs , volume 12 . Abstract Six new caryophyllene-based sesquiterpenoids named punctaporonins H–M (1–6), together with punctaporonin B (7) and humulane (8) were isolated from the fermentation broth of the sponge-derived fungus Hansfordia sinuosae. Their structures were determined by the extensive HRESIMS and NMR spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurations of punctaporonins H–I (1–2). The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113805
42
42
Oct 12, 2014
10/14
Oct 12, 2014
by
Mehrabadi, Azar; Liu, Shiliang; Bartholomew, Sharon; Hutcheon, Jennifer A; Magee, Laura A; Kramer, Michael S; Liston, Robert M; Joseph, K S
texts
eye 42
favorite 0
comment 0
This article is from BMJ : British Medical Journal , volume 349 . Abstract Objective To examine whether changes in postpartum haemorrhage, hypertensive disorders of pregnancy, or other risk factors explain the increase in obstetric acute renal failure in Canada.Design Retrospective cohort study.Setting Canada (excluding the province of Quebec).Participants All hospital deliveries from 2003 to 2010 (n=2 193 425).Main outcome measures Obstetric acute renal failure identified by ICD-10...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115671
50
50
Oct 12, 2014
10/14
Oct 12, 2014
by
Liu, Yi-Nan; Yan, Yan; Li, Shi-Jie; Liu, Hui; Wu, Qi; Zhang, Li-Jian; Yang, Yue; Chen, Jin-Feng
texts
eye 50
favorite 0
comment 0
This article is from World Journal of Surgical Oncology , volume 12 . Abstract Background: A gastroesophageal anastomotic fistula remains a potentially life-threatening post-esophagectomy complication. To promote fistula closure, we developed a modified endoscopic method of trans-fistula drainage with persistent negative pressure. In this study, we aimed to evaluate the efficacy of this endoscopic therapy. Methods: Between June and November 2013, five male patients with post-surgical esophageal...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119058
54
54
Oct 12, 2014
10/14
Oct 12, 2014
by
Guerrero, Erick G; Villatoro, Jorge Ameth; Kong, Yinfei; Fleiz, Clara; Vega, William A; Strathdee, Steffanie A; Medina-Mora, Maria Elena
texts
eye 54
favorite 0
comment 0
This article is from Substance Abuse Treatment, Prevention, and Policy , volume 9 . Abstract Background: We examined Mexican migrants’ perceived barriers to entering substance abuse treatment and potential differences by gender. Methods: This study analyzed a subset of household data collected in Mexico in 2011 via the Encuesta Nacional de Adicciones (National Survey of Addictions). A sample of 1,143 individuals who reported using illicit drugs was analyzed using multivariate negative...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118628
67
67
Oct 12, 2014
10/14
Oct 12, 2014
by
Aahlin, Eirik K; von Meyenfeldt, Maarten; Dejong, Cornelius HC; Ljungqvist, Olle; Fearon, Kenneth C; Lobo, Dileep N; Demartines, Nicolas; Revhaug, Arthur; Wigmore, Stephen J; Lassen, Kristoffer
texts
eye 67
favorite 0
comment 0
This article is from Perioperative Medicine , volume 3 . Abstract Background: The aim of this study was to survey the relative importance of postoperative recovery targets and perioperative care items, as perceived by a large group of international dedicated professionals. Methods: A questionnaire with eight postoperative recovery targets and 13 perioperative care items was mailed to participants of the first international Enhanced Recovery After Surgery (ERAS) congress and to authors of papers...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118075
58
58
Oct 12, 2014
10/14
Oct 12, 2014
by
Xavier, Basil Britto; Sabirova, Julia; Pieter, Moons; Hernalsteens, Jean-Pierre; de Greve, Henri; Goossens, Herman; Malhotra-Kumar, Surbhi
texts
eye 58
favorite 0
comment 0
This article is from BMC Research Notes , volume 7 . Abstract Background: De novo genome assembly can be challenging due to inherent properties of the reads, even when using current state-of-the-art assembly tools based on de Bruijn graphs. Often users are not bio-informaticians and, in a black box approach, utilise assembly parameters such as contig length and N50 to generate whole genome sequences, potentially resulting in mis-assemblies. Findings: Utilising several assembly tools based on de...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118782
71
71
Oct 12, 2014
10/14
Oct 12, 2014
by
Bragstad, Line Kildal; Kirkevold, Marit; Foss, Christina
texts
eye 71
favorite 0
comment 0
This article is from BMC Health Services Research , volume 14 . Abstract Background: The care policy and organization of the care sector is shifting to accommodate projected demographic changes and to ensure a sustainable model of health care provision in the future. Adult children and spouses are often the first to assume care giving responsibilities for older adults when declining function results in increased care needs. By introducing policies tailored to enabling family members to combine...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119054
58
58
Oct 12, 2014
10/14
Oct 12, 2014
by
Nanjidsuren, Tsevelmaa; Min, Kwan-Sik
texts
eye 58
favorite 0
comment 0
This article is from BMC Biotechnology , volume 14 . Abstract Background: Monkey 20α-hydroxysteroid dehydrogenase (20α-HSD) is a catabolic enzyme responsible for converting progesterone into biologically inactive 20α-hydroxyprogesterone, thereby playing a key role in the estrous cycle or pregnancy and allowing ovulation and parturition to occur in most mammalian animals. Monkey 20α-HSD was highly abundant in ovarian and placental tissues during the pre-ovulation and pre-parturition phase...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118612
50
50
Oct 12, 2014
10/14
Oct 12, 2014
by
Chen, Hongfei; Xia, Yun; Zhu, Binbin; Hu, Xiawei; Xu, Shihao; Chen, Limei; Papadimos, Thomas J; Wang, Wantie; Wang, Quanguang; Xu, Xuzhong
texts
eye 50
favorite 0
comment 0
This article is from BMC Anesthesiology , volume 14 . Abstract Background: The reversal efficacy of 2% lipid emulsion in cardiac asystole induced by different concentrations of bupivacaine is poorly defined and needs to be determined. Methods: Forty-two male Sprague–Dawley rats were randomly divided into seven groups: B40, B60, B80, B100, B120, B140 and B160, n = 6. The Langendorff isolated heart perfusion model was used, which consisted of a balanced perfusion with Krebs-Henseleit...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118607
64
64
Oct 11, 2014
10/14
Oct 11, 2014
by
Kenett, Dror Y.; Morstatter, Fred; Stanley, H. Eugene; Liu, Huan
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Twitter is a major social media platform in which users send and read messages (“tweets”) of up to 140 characters. In recent years this communication medium has been used by those affected by crises to organize demonstrations or find relief. Because traffic on this media platform is extremely heavy, with hundreds of millions of tweets sent every day, it is difficult to differentiate between times of turmoil and times of typical discussion....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116114
84
84
Oct 11, 2014
10/14
Oct 11, 2014
by
Melville, Jane; Smith, Katie; Hobson, Rod; Hunjan, Sumitha; Shoo, Luke
texts
eye 84
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Molecular phylogenetics is increasingly highlighting the prevalence of cryptic species, where morphologically similar organisms have long independent evolutionary histories. When such cryptic species are known to be declining in numbers and are at risk of extinction due to a range of threatening processes, the disjunction between molecular systematics research and conservation policy becomes a significant problem. We investigate the taxonomic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116116
84
84
Oct 11, 2014
10/14
Oct 11, 2014
by
Regan, Fran H.; Hockenhull, Jo; Pritchard, Joy C.; Waterman-Pearson, Avril E.; Whay, Helen R.
texts
eye 84
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: The donkey has a reputation for stoicism and its behavioural repertoire in clinical contexts is under-reported. Lack of understanding of the norms of donkey behaviour and how it may vary over time can compromise use of behavioural measures as indicators of pain or emotional state. The objective of this study was to find out whether the behaviour of working donkeys was influenced by gender, the time of day or differed between days...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116118
65
65
Oct 11, 2014
10/14
Oct 11, 2014
by
Abbott, Danielle S.; Chin-Smith, Evonne C.; Seed, Paul T.; Chandiramani, Manju; Shennan, Andrew H.; Tribe, Rachel M.
texts
eye 65
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Early spontaneous preterm birth is associated with inflammation/infection and shortening of the cervix. We hypothesised that cervico-vaginal production of trappin2/elafin (peptidase inhibitor 3) and cathelicidin antimicrobial peptide (cathelicidin), key components of the innate immune system, are altered in women who have a spontaneous preterm birth. The aim was to determine the relationship between cervico-vaginal fluid (CVF) trappin2/elafin...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116119
53
53
Oct 11, 2014
10/14
Oct 11, 2014
by
Willcox, Merlin L.; Dicko, Moussa I.; Graz, Bertrand; Forster, Mathieu; Shinkins, Bethany; Diakite, Chiaka; Giani, Sergio; Falquet, Jacques; Diallo, Drissa; Dembele, Eugene
texts
eye 53
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Inpatient case fatality from severe malaria remains high in much of sub-Saharan Africa. The majority of these deaths occur within 24 hours of admission, suggesting that pre-hospital management may have an impact on the risk of case fatality. Methods: Prospective cohort study, including questionnaire about pre-hospital treatment, of all 437 patients admitted with severe febrile illness (presumed to be severe malaria) to the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116122
111
111
Oct 11, 2014
10/14
Oct 11, 2014
by
Sampasa-Kanyinga, Hugues; Roumeliotis, Paul; Xu, Hao
texts
eye 111
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Purpose: The negative effects of peer aggression on mental health are key issues for public health. The purpose of this study was to examine the associations between cyberbullying and school bullying victimization with suicidal ideation, plans and attempts among middle and high school students, and to test whether these relationships were mediated by reports of depression. Methods: Data for this study are from the 2011 Eastern Ontario Youth...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116124
67
67
Oct 11, 2014
10/14
Oct 11, 2014
by
Escalera-Zamudio, Marina; Nelson, Martha I.; Cobian Guemes, Ana Georgina; Lopez-Martinez, Irma; Cruz-Ortiz, Natividad; Iguala-Vidales, Miguel; Garcia, Elvia Rodriguez; Barrera-Badillo, Gisela; Diaz-Quinonez, Jose Alberto; Lopez, Susana; Arias, Carlos F.; Isa, Pavel
texts
eye 67
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract In this work, nineteen influenza A/H3N2 viruses isolated in Mexico between 2003 and 2012 were studied. Our findings show that different human A/H3N2 viral lineages co-circulate within a same season and can also persist locally in between different influenza seasons, increasing the chance for genetic reassortment events. A novel minor cluster was also identified, named here as Korea, that circulated worldwide during 2003. Frequently,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116128
64
64
Oct 11, 2014
10/14
Oct 11, 2014
by
Guillera-Arroita, Gurutzeta; Lahoz-Monfort, Jose J.; MacKenzie, Darryl I.; Wintle, Brendan A.; McCarthy, Michael A.
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract In a recent paper, Welsh, Lindenmayer and Donnelly (WLD) question the usefulness of models that estimate species occupancy while accounting for detectability. WLD claim that these models are difficult to fit and argue that disregarding detectability can be better than trying to adjust for it. We think that this conclusion and subsequent recommendations are not well founded and may negatively impact the quality of statistical inference in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116132
47
47
Oct 11, 2014
10/14
Oct 11, 2014
by
Vangone, Anna; Abdel-Azeim, Safwat; Caputo, Ivana; Sblattero, Daniele; Di Niro, Roberto; Cavallo, Luigi; Oliva, Romina
texts
eye 47
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Anti-idiotype antibodies have potential therapeutic applications in many fields, including autoimmune diseases. Herein we report the isolation and characterization of AIM2, an anti-idiotype antibody elicited in a mouse model upon expression of the celiac disease-specific autoantibody MB2.8 (directed against the main disease autoantigen type 2 transglutaminase, TG2). To characterize the interaction between the two antibodies, a 3D model of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116137
64
64
Oct 11, 2014
10/14
Oct 11, 2014
by
Harper, Diane M.; Else, Britney M.; Bartley, Mitchell J.; Arey, Anne M.; Barnett, Angela L.; Rosemergey, Beth E.; Paynter, Christopher A.; Verdenius, Inge; Harper, Sean M.; Harris, George D.; Groner, Jennifer A.; Malnar, Gerard J.; Wall, Jeffrey; Bonham, Aaron J.
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Objectives: Obesity adversely inhibits antibody response to vaccination. Three doses of HPV4 may or may not provide adequate long term protection against HPV 16/18 in obese females. The aim of this study was to determine whether adherence to HPV4 vaccination in a safety net population was reduced with increasing body mass index (BMI). Methods: We designed a historical prospective study evaluating the number and dates of HPV4 dosing that...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116139
61
61
Oct 11, 2014
10/14
Oct 11, 2014
by
Nagy, Alexander; Cernikova, Lenka; Jirincova, Helena; Havlickova, Martina; Hornickova, Jitka
texts
eye 61
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Influenza A virus (IAV) in wild bird reservoir hosts is characterized by the perpetuation in a plethora of subtype and genotype constellations. Multiyear monitoring studies carried out during the last two decades worldwide have provided a large body of knowledge regarding the ecology of IAV in wild birds. Nevertheless, other issues of avian IAV evolution have not been fully elucidated, such as the complexity and dynamics of genetic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116140
56
56
Oct 11, 2014
10/14
Oct 11, 2014
by
Ullal-Gupta, Sangeeta; Hannon, Erin E.; Snyder, Joel S.
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Musical meters vary considerably across cultures, yet relatively little is known about how culture-specific experience influences metrical processing. In Experiment 1, we compared American and Indian listeners' synchronous tapping to slow sequences. Inter-tone intervals contained silence or to-be-ignored rhythms that were designed to induce a simple meter (familiar to Americans and Indians) or a complex meter (familiar only to Indians). A...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116158
85
85
Oct 11, 2014
10/14
Oct 11, 2014
by
Liu, Ya-Wei; Huang, Yi-Tsau
texts
eye 85
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Anti-inflammation via inhibition of NF-κB pathways in hepatic stellate cells (HSCs) is one therapeutic approach to hepatic fibrosis. Tanshinone IIA (C19H18O3, Tan IIA) is a lipophilic diterpene isolated from Salvia miltiorrhiza Bunge, with reported anti-inflammatory activity. We tested whether Tan IIA could inhibit HSC activation. Materials and Methods: The cell line of rat hepatic stellate cells (HSC-T6) was stimulated with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116159
64
64
Oct 11, 2014
10/14
Oct 11, 2014
by
Lu, Ning; Karlsen, Tine V.; Reed, Rolf K.; Kusche-Gullberg, Marion; Gullberg, Donald
texts
eye 64
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract We have previously shown that fibroblast expression of α11β1 integrin stimulates A549 carcinoma cell growth in a xenograft tumor model. To understand the molecular mechanisms whereby a collagen receptor on fibroblast can regulate tumor growth we have used a 3D heterospheroid system composed of A549 tumor cells and fibroblasts without (α11+/+) or with a deletion (α11-/-) in integrin α11 gene. Our data show that α11-/-/A549 spheroids are...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116160
207
207
Oct 11, 2014
10/14
Oct 11, 2014
by
Freeth, Tony
texts
eye 207
favorite 1
comment 0
This article is from PLoS ONE , volume 9 . Abstract The ancient Greek astronomical calculating machine, known as the Antikythera Mechanism, predicted eclipses, based on the 223-lunar month Saros cycle. Eclipses are indicated on a four-turn spiral Saros Dial by glyphs, which describe type and time of eclipse and include alphabetical index letters, referring to solar eclipse inscriptions. These include Index Letter Groups, describing shared eclipse characteristics. The grouping and ordering of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116162
58
58
Oct 11, 2014
10/14
Oct 11, 2014
by
Freeman, Tom C. A.; Leung, Johahn; Wufong, Ella; Orchard-Mills, Emily; Carlile, Simon; Alais, David
texts
eye 58
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Evidence that the auditory system contains specialised motion detectors is mixed. Many psychophysical studies confound speed cues with distance and duration cues and present sound sources that do not appear to move in external space. Here we use the ‘discrimination contours’ technique to probe the probabilistic combination of speed, distance and duration for stimuli moving in a horizontal arc around the listener in virtual auditory space....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116163
69
69
Oct 11, 2014
10/14
Oct 11, 2014
by
Goodreau, Steven M.; Carnegie, Nicole B.; Vittinghoff, Eric; Lama, Javier R.; Fuchs, Jonathan D.; Sanchez, Jorge; Buchbinder, Susan P.
texts
eye 69
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Three trials have demonstrated the prophylactic effect of male circumcision (MC) for HIV acquisition among heterosexuals, and MC interventions are underway throughout sub-Saharan Africa. Similar efforts for men who have sex with men (MSM) are stymied by the potential for circumcised MSM to acquire HIV easily through receptive sex and transmit easily through insertive sex. Existing work suggests that MC for MSM should reach its...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116164
43
43
Oct 11, 2014
10/14
Oct 11, 2014
by
Botman, Daniel; Rottinger, Eric; Martindale, Mark Q.; de Jong, Johann; Kaandorp, Jaap A.
texts
eye 43
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: The starlet sea anemone Nematostella vectensis is a diploblastic cnidarian that expresses a set of conserved genes for gut formation during its early development. During the last decade, the spatial distribution of many of these genes has been visualized with RNA hybridization or protein immunolocalization techniques. However, due to N. vectensis' curved and changing morphology, quantification of these spatial data is problematic....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116165
102
102
Oct 11, 2014
10/14
Oct 11, 2014
by
Chang, Yi-Shin; Owen, Julia P.; Desai, Shivani S.; Hill, Susanna S.; Arnett, Anne B.; Harris, Julia; Marco, Elysa J.; Mukherjee, Pratik
texts
eye 102
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Over 90% of children with Autism Spectrum Disorders (ASD) demonstrate atypical sensory behaviors. In fact, hyper- or hyporeactivity to sensory input or unusual interest in sensory aspects of the environment is now included in the DSM-5 diagnostic criteria. However, there are children with sensory processing differences who do not meet an ASD diagnosis but do show atypical sensory behaviors to the same or greater degree as ASD children. We...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116166
49
49
Oct 11, 2014
10/14
Oct 11, 2014
by
Kerkhoff, Andrew D.; Wood, Robin; Vogt, Monica; Lawn, Stephen D.
texts
eye 49
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Detection of the mycobacterial cell wall antigen lipoarabinomannan (LAM) in urine can be used to diagnose HIV-associated tuberculosis (TB) using a qualitative (positive/negative) read-out. However, it is not known whether the quantity of LAM present in urine provides additional prognostic information. Methods/Findings: Consecutively recruited adult outpatients initiating antiretroviral therapy (ART) in South Africa were...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116167
77
77
Oct 11, 2014
10/14
Oct 11, 2014
by
Saporiti, Fabiana; Bearhop, Stuart; Silva, Laura; Vales, Damian G.; Zenteno, Lisette; Crespo, Enrique A.; Aguilar, Alex; Cardona, Luis
texts
eye 77
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The human exploitation of marine resources is characterised by the preferential removal of the largest species. Although this is expected to modify the structure of food webs, we have a relatively poor understanding of the potential consequences of such alteration. Here, we take advantage of a collection of ancient consumer tissues, using stable isotope analysis and SIBER to assess changes in the structure of coastal marine food webs in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116168
70
70
Oct 11, 2014
10/14
Oct 11, 2014
by
Egekwu, Noble; Sonenshine, Daniel E.; Bissinger, Brooke W.; Roe, R. Michael
texts
eye 70
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods. However, for molecular processes, it was more successful for the Illumina samples than for 454 samples. Functional assignments of transcripts predicting neuropeptides, neuropeptide receptors, neurotransmitter receptors and other...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116169
56
56
Oct 11, 2014
10/14
Oct 11, 2014
by
Viguiliouk, Effie; Kendall, Cyril W. C.; Blanco Mejia, Sonia; Cozma, Adrian I.; Ha, Vanessa; Mirrahimi, Arash; Jayalath, Viranda H.; Augustin, Livia S. A.; Chiavaroli, Laura; Leiter, Lawrence A.; de Souza, Russell J.; Jenkins, David J. A.; Sievenpiper, John L.
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Tree nut consumption has been associated with reduced diabetes risk, however, results from randomized trials on glycemic control have been inconsistent. Objective: To provide better evidence for diabetes guidelines development, we conducted a systematic review and meta-analysis of randomized controlled trials to assess the effects of tree nuts on markers of glycemic control in individuals with diabetes. Data Sources: MEDLINE,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116170
68
68
Oct 11, 2014
10/14
Oct 11, 2014
by
Hessamfar, Mojgan; Colin, Celine; Bruyand, Mathias; Decoin, Madeleine; Bonnet, Fabrice; Mercie, Patrick; Neau, Didier; Cazanave, Charles; Pellegrin, Jean-Luc; Dabis, Francois; Morlat, Philippe; Chene, Genevieve
texts
eye 68
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Objective: To describe trends and determinants of severe morbidity in HIV-infected women and men. Design: A French prospective cohort of HIV-infected patients of both sexes and all transmission categories. Methods: We used hospital admission data from January 2000 to December 2008. A severe morbid event (SME) was defined as a clinical event requiring hospitalization for ≥48 h, several events could be reported during hospitalization. Yearly...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116171
63
63
Oct 11, 2014
10/14
Oct 11, 2014
by
Normark, Johan; Nelson, Maria; Engstrom, Patrik; Andersson, Marie; Bjork, Rafael; Moritz, Thomas; Fahlgren, Anna; Bergstrom, Sven
texts
eye 63
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract In the Plasmodium infected host, a balance between pro- and anti-inflammatory responses is required to clear the parasites without inducing major host pathology. Clinical reports suggest that bacterial infection in conjunction with malaria aggravates disease and raises both mortality and morbidity in these patients. In this study, we investigated the immune responses in BALB/c mice, co-infected with Plasmodium berghei NK65 parasites and the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116174
56
56
Oct 11, 2014
10/14
Oct 11, 2014
by
Golden-Mason, Lucy; Hahn, Young S.; Strong, Michael; Cheng, Linling; Rosen, Hugo R.
texts
eye 56
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Background: Hepatitis C viral (HCV) proteins, including core, demonstrate immuno-modulatory properties; however, the effect of extracellular core on natural killer (NK) cells has not previously been investigated. Aims: To characterise NKs in acute HCV infection over time, and, to examine the effect of exogenous HCV-core protein on NK cell phenotype and function. Methods: Acute HCV patients (n = 22), including 10 subjects who spontaneously...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116173
60
60
Oct 11, 2014
10/14
Oct 11, 2014
by
Won, Jong Chul; Park, Cheol-Young; Oh, Sang Woo; Lee, Eon Sook; Youn, Byung-Soo; Kim, Min-Seon
texts
eye 60
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Obesity and insulin resistance are hallmarks of the metabolic syndrome, which is associated with low-grade chronic inflammation. Clusterin/apolipoprotein J is an abundant plasma chaperone protein that has recently been suggested as a potential biomarker that reflects the inflammatory process in Alzheimer's disease. In the present study, we investigated anthropometric and clinical factors affecting the plasma levels of clusterin in healthy...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116172
65
65
Oct 11, 2014
10/14
Oct 11, 2014
by
Horacio, Andreia N.; Lopes, Joana P.; Ramirez, Mario; Melo-Cristino, Jose
texts
eye 65
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract There is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci causing NIPP in adults to determine recent changes in serotype prevalence, the potential coverage of pneumococcal vaccines and changes in antimicrobial resistance. Serotypes and antimicrobial susceptibility profiles of a sample of 1300 isolates recovered from adult patients (≥18 yrs) between 1999 and 2011...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116175
87
87
Oct 11, 2014
10/14
Oct 11, 2014
by
Shamshirband, Shahaboddin; Petkovic, Dalibor; Hashim, Roslan; Motamedi, Shervin
texts
eye 87
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Wind turbine noise is one of the major obstacles for the widespread use of wind energy. Noise tone can greatly increase the annoyance factor and the negative impact on human health. Noise annoyance caused by wind turbines has become an emerging problem in recent years, due to the rapid increase in number of wind turbines, triggered by sustainable energy goals set forward at the national and international level. Up to now, not all aspects of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116176
80
80
Oct 11, 2014
10/14
Oct 11, 2014
by
Ferrero, Valentina Elisabetta Viviana; Pedotti, Mattia; Chiado, Alessandro; Simonelli, Luca; Calzolai, Luigi; Varani, Luca; Lettieri, Teresa
texts
eye 80
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract In this manuscript, we modulate the binding properties of estrogen receptor protein by rationally modifying the amino acid composition of its ligand binding domain. By combining sequence alignment and structural analysis of known estrogen receptor-ligand complexes with computational analysis, we were able to predict estrogen receptor mutants with altered binding properties. These predictions were experimentally confirmed by producing single...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116177
57
57
Oct 11, 2014
10/14
Oct 11, 2014
by
Blaho, Miklos; Herczeg, Tamas; Kriska, Gyorgy; Egri, Adam; Szaz, Denes; Farkas, Alexandra; Tarjanyi, Nikolett; Czinke, Laszlo; Barta, Andras; Horvath, Gabor
texts
eye 57
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The horizontally polarizing surface parts of shiny black cars (the reflection-polarization characteristics of which are similar to those of water surfaces) attract water-leaving polarotactic insects. Thus, shiny black cars are typical sources of polarized light pollution endangering water-leaving insects. A new fashion fad is to make car-bodies matt black or grey. Since rough (matt) surfaces depolarize the reflected light, one of the ways of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116178
68
68
Oct 11, 2014
10/14
Oct 11, 2014
by
Webber, Amanda D.; Hill, Catherine M.
texts
eye 68
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Considering how people perceive risks to their livelihoods from local wildlife is central to (i) understanding the impact of crop damage by animals on local people and (ii) recognising how this influences their interactions with, and attitudes towards, wildlife. Participatory risk mapping (PRM) is a simple, analytical tool that can be used to identify and classify risk within communities. Here we use it to explore local people's perceptions of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116180
61
61
Oct 11, 2014
10/14
Oct 11, 2014
by
Davis, Michael S.; Bonen, Arend; Snook, Laelie A.; Jain, Swati S.; Bartels, Kenneth; Geor, Raymond; Hueffer, Karsten
texts
eye 61
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Endurance exercise relies on transsarcolemmal flux of substrates in order to avoid depletion of intramuscular reserves. Previous studies of endurance trained sled dogs have shown a remarkable capacity of these dogs to adapt rapidly to endurance exercise by decreasing the utilization of intramuscular reserves. The current study tested the hypothesis that the dogs' glycogen-sparing phenotype is due to increased sarcolemmal transport of glucose...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116179
60
60
Oct 11, 2014
10/14
Oct 11, 2014
by
Puechmaille, Sebastien J.; Borissov, Ivailo M.; Zsebok, Sandor; Allegrini, Benjamin; Hizem, Mohammed; Kuenzel, Sven; Schuchmann, Maike; Teeling, Emma C.; Siemers, Bjorn M.
texts
eye 60
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Animals employ an array of signals (i.e. visual, acoustic, olfactory) for communication. Natural selection favours signals, receptors, and signalling behaviour that optimise the received signal relative to background noise. When the signal is used for more than one function, antagonisms amongst the different signalling functions may constrain the optimisation of the signal for any one function. Sexual selection through mate choice can strongly...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116191
62
62
Oct 11, 2014
10/14
Oct 11, 2014
by
Shi, Feng; Shi, Jikui; Li, Yongfu
texts
eye 62
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract To obtain a water-soluble β-D-glucan derivative cleanly and conveniently, a highly efficient mechanochemical method, planetary ball milling, was used to phosphorylate β-D-glucan isolated from yeast Saccharomyces cerevisiae in solid state. Soluble β-D-glucan phosphate (GP) with a high degree of substitution (0.77–2.09) and an apparent PEAK molecular weight of 6.6–10.0 kDa was produced when β-D-glucan was co-milled with sodium...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116193
60
60
Oct 11, 2014
10/14
Oct 11, 2014
by
Robison, Bruce; Seibel, Brad; Drazen, Jeffrey
texts
eye 60
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Octopuses typically have a single reproductive period and then they die (semelparity). Once a clutch of fertilized eggs has been produced, the female protects and tends them until they hatch. In most shallow-water species this period of parental care can last from 1 to 3 months, but very little is known about the brooding of deep-living species. In the cold, dark waters of the deep ocean, metabolic processes are often slower than their...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116195
50
50
Oct 11, 2014
10/14
Oct 11, 2014
by
Chou, Hong; Wu, Keh-Gong; Yeh, Chang-Ching; Tai, Hsiao-Yun; Tam, Ming F.; Chen, Yu-Sen; Shen, Horng-Der
texts
eye 50
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Fusarium species are among airborne fungi and recognized as causative agents of human atopic disorders. However, Fusarium allergens have not been well characterized and the lack of information limits clinical diagnosis and treatment of fungal allergy. The purpose of this study is to identify and characterize important allergens of F. proliferatum. IgE-reacting F. proliferatum components were identified by immunoblot using serum samples from...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116196
90
90
Oct 11, 2014
10/14
Oct 11, 2014
by
Favaro, Livio; Ozella, Laura; Pessani, Daniela
texts
eye 90
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The African Penguin (Spheniscus demersus) is a highly social and vocal seabird. However, currently available descriptions of the vocal repertoire of African Penguin are mostly limited to basic descriptions of calls. Here we provide, for the first time, a detailed description of the vocal behaviour of this species by collecting audio and video recordings from a large captive colony. We combine visual examinations of spectrograms with spectral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116197
52
52
Oct 11, 2014
10/14
Oct 11, 2014
by
Yeom, Hong Gi; Kim, June Sic; Chung, Chun Kee
texts
eye 52
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Sensory feedback is very important for movement control. However, feedback information has not been directly used to update movement prediction model in the previous BMI studies, although the closed-loop BMI system provides the visual feedback to users. Here, we propose a BMI framework combining image processing as the feedback information with a novel prediction method. The feedback-prediction algorithm (FPA) generates feedback information...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116198
