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Oct 6, 2014
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Nakamura, Kazufumi; Oe, Hiroki; Kihara, Hajime; Shimada, Kenei; Fukuda, Shota; Watanabe, Kyoko; Takagi, Tsutomu; Yunoki, Kei; Miyoshi, Toru; Hirata, Kumiko; Yoshikawa, Junichi; Ito, Hiroshi
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This article is from Cardiovascular Diabetology , volume 13 . Abstract Background: Alpha glucosidase inhibitor (GI) attenuates postprandial hyperglycemia (PPH) and reduces the risk of cardiovascular events in patients with impaired glucose tolerance or type 2 diabetes. Dipeptidyl peptidase 4 (DPP-4) inhibitors also attenuate PPH. PPH is one of the factors leading to endothelial dysfunction which is an early event in the pathogenesis of atherosclerosis. Furthermore, DPP-4 inhibitors protect...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149239
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Oct 11, 2014
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Robison, Bruce; Seibel, Brad; Drazen, Jeffrey
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This article is from PLoS ONE , volume 9 . Abstract Octopuses typically have a single reproductive period and then they die (semelparity). Once a clutch of fertilized eggs has been produced, the female protects and tends them until they hatch. In most shallow-water species this period of parental care can last from 1 to 3 months, but very little is known about the brooding of deep-living species. In the cold, dark waters of the deep ocean, metabolic processes are often slower than their...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116195
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Oct 7, 2014
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Ahmed, Ashik; Al-Amin, Rasheduzzaman; Amin, Ruhul
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This article is from SpringerPlus , volume 3 . Abstract This paper proposes designing of Static Synchronous Series Compensator (SSSC) based damping controller to enhance the stability of a Single Machine Infinite Bus (SMIB) system by means of Invasive Weed Optimization (IWO) technique. Conventional PI controller is used as the SSSC damping controller which takes rotor speed deviation as the input. The damping controller parameters are tuned based on time integral of absolute error based cost...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137048
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Oct 5, 2014
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Nelson, Heidi D.; Weerasinghe, Roshanthi; Martel, Maritza; Bifulco, Carlo; Assur, Ted; Elmore, Joann G.; Weaver, Donald L.
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This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Health care systems rely on electronic patient data, yet access to breast tissue pathology results continues to depend on interpreting dictated free-text reports. Objective:: The objective was to develop a method to electronically search and categorize pathologic diagnoses of patients’ breast tissue specimens from dictated free-text pathology reports in a large health system for multiple users including...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141424
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Oct 7, 2014
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Chigira, Yuusuke; Takai, Tomoko; Oda, Takahiro; Dobashi, Kunio
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This article is from Journal of Physical Therapy Science , volume 26 . Abstract [Purpose] The purpose of this study was to investigate differences in effects caused by variation in the intervention frequency of outpatient pulmonary rehabilitation, in terms of the pulmonary function, lower-limb muscle strength, exercise tolerance, and quality of life (QOL). [Subjects and Methods] A total of 36 patients with mild to severe chronic obstructive pulmonary disease (COPD) were studied. These patients...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135193
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Oct 8, 2014
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Goto, Yumeno; Jono, Yasutomo; Hatanaka, Ryota; Nomura, Yoshifumi; Tani, Keisuke; Chujo, Yuta; Hiraoka, Koichi
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This article is from Frontiers in Human Neuroscience , volume 8 . Abstract We investigated differences in corticospinal and spinal control between discrete and rhythmic ankle movements. Motor evoked potentials (MEPs) in the tibialis anterior and soleus muscles and soleus H-reflex were elicited in the middle of the plantar flexion phase during discrete ankle movement or in the initial or later cycles of rhythmic ankle movement. The H-reflex was evoked at an intensity eliciting a small M-wave and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115592
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Oct 8, 2014
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Wilson, C. Brad; McLaughlin, Leslie D.; Ebenezer, Philip J.; Nair, Anand R.; Dange, Rahul; Harre, Joseph G.; Shaak, Thomas L.; Diamond, David M.; Francis, Joseph
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This article is from Frontiers in Behavioral Neuroscience , volume 8 . Abstract Serotonin (5-HT), norepinephrine (NE), and other neurotransmitters are modulated in post-traumatic stress disorder (PTSD). In addition, pro-inflammatory cytokines (PIC) are elevated during the progression of the disorder. Currently, the only approved pharmacologic treatments for PTSD are the selective-serotonin reuptake inhibitors (SSRI) sertraline and paroxetine, but their efficacy in treating PTSD is marginal at...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115632
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Oct 6, 2014
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Sharma, Monal; Rawal, Leena; Panwar, Deepak; Sehgal, Neeta; Ali, Sher
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This article is from BMC Genomics , volume 15 . Abstract Background: The Homeobox (Hox) family complex contains 39 genes, clustered into four groups (A-D) all expressing in sequential manner. The HOX proteins are transcriptional factors involved in regulation of pattern formation of the anterio-posterior body axis across the species. Most of the Hox family genes have been studied with respect to their organization and expression during the embryonic stages. However, expression pattern of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139611
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Oct 11, 2014
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Kenett, Dror Y.; Morstatter, Fred; Stanley, H. Eugene; Liu, Huan
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This article is from PLoS ONE , volume 9 . Abstract Twitter is a major social media platform in which users send and read messages (“tweets”) of up to 140 characters. In recent years this communication medium has been used by those affected by crises to organize demonstrations or find relief. Because traffic on this media platform is extremely heavy, with hundreds of millions of tweets sent every day, it is difficult to differentiate between times of turmoil and times of typical discussion....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116114
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Oct 2, 2014
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Marisi, Giorgia; Passardi, Alessandro; Calistri, Daniele; Zoli, Wainer; Amadori, Dino; Ulivi, Paola
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This article is from International Journal of Molecular Sciences , volume 15 . Abstract Single nucleotide polymorphisms (SNPs) may be associated with the response or toxicity to different types of treatment. Although SNP analysis is usually performed on DNA from peripheral blood, formalin fixed paraffin-embedded (FFPE) tissue is often used for retrospective studies. We analyzed VEGF (−2578C>A, −1498C>T, −1154G>A, −634C>G, +936C>T) and eNOS (+894G>T, −786T>C, VNTR...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159797
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Oct 11, 2014
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Freeman, Tom C. A.; Leung, Johahn; Wufong, Ella; Orchard-Mills, Emily; Carlile, Simon; Alais, David
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This article is from PLoS ONE , volume 9 . Abstract Evidence that the auditory system contains specialised motion detectors is mixed. Many psychophysical studies confound speed cues with distance and duration cues and present sound sources that do not appear to move in external space. Here we use the ‘discrimination contours’ technique to probe the probabilistic combination of speed, distance and duration for stimuli moving in a horizontal arc around the listener in virtual auditory space....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116163
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Oct 10, 2014
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Dawson, Anna M; Taylor, Rachael W; Williams, Sheila M; Taylor, Barry J; Brown, Deirdre A
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This article is from BMJ Open , volume 4 . Abstract Objectives: As parents of young children are often unaware their child is overweight, screening provides the opportunity to inform parents and provide the impetus for behaviour change. We aimed to determine if parents could recall and understand the information they received about their overweight child after weight screening. Design: Randomised controlled trial of different methods of feedback. Setting: Participants were recruited through...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120339
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Oct 11, 2014
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Diekhof, Esther Kristina; Wittmer, Susanne; Reimers, Luise
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This article is from PLoS ONE , volume 9 . Abstract Parochial altruism, defined as increased ingroup favoritism and heightened outgroup hostility, is a widespread feature of human societies that affects altruistic cooperation and punishment behavior, particularly in intergroup conflicts. Humans tend to protect fellow group members and fight against outsiders, even at substantial costs for themselves. Testosterone modulates responses to competition and social threat, but its exact role in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116333
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Oct 3, 2014
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Sakai, Ryo; Winand, Raf; Verbeiren, Toni; Moere, Andrew Vande; Aerts, Jan
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This article is from F1000Research , volume 3 . Abstract Dendrograms are graphical representations of binary tree structures resulting from agglomerative hierarchical clustering. In Life Science, a cluster heat map is a widely accepted visualization technique that utilizes the leaf order of a dendrogram to reorder the rows and columns of the data table. The derived linear order is more meaningful than a random order, because it groups similar items together. However, two consecutive items...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162509
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Oct 2, 2014
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Shen, Zhenwei; Fang, Lu; Zhao, Liming; Lei, Han
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This article is from International Journal of Molecular Sciences , volume 15 . Abstract An important member of the defensin family, β-defensin 2, is believed to play an important role in defense against foreign pathogens. In the present study, we constructed lentiviral vectors to express and knockdown β-defensin 2 in rat lungs. The results showed that the infection of β-defensin 2 overexpression lentivirus and β-defensin 2 shRNA effectively increased and suppressed the expression of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159799