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Oct 10, 2014
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Zhou, Lili; Zheng, Shouyan; Xiao, Qiuyan; Ren, Luo; Xie, Xiaohong; Luo, Jian; Wang, Lijia; Huang, Ailong; Liu, Wei; Liu, Enmei
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This article is from BMC Infectious Diseases , volume 14 . Abstract Background: Human bocavirus is a newly discovered parvovirus. Multiple studies have confirmed the presence of human bocavirus1 (HBoV1) in respiratory tract samples of children. The viral load, presentation of single detection and its role as a causative agent of severe respiratory tract infections have not been thoroughly elucidated. Methods: We investigated the presence of HBoV1 by quantitative polymerase chain reaction (PCR)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125703
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72
Oct 9, 2014
10/14
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Yun, Sangchul; Woo, Hee-Doo; Doo, Seung-Whan; Kwon, Soon Hyo; Noh, Hyunjin; Song, Dan
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This article is from Journal of Korean Medical Science , volume 29 . Abstract A 34-yr-old female was diagnosed as being brain dead. Preoperative ultrasound revealed no abnormal focal lesions. However, the horseshoe kidney was identified during organ harvest. En bloc nephrectomy was performed. The kidney was divided at the midline of isthmus. The divided right kidney was discarded due to numerous arteries and veins. The divided left kidney was transplanted. After declamping, the kidney was well...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129212
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Oct 6, 2014
10/14
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Yeh, Po-Yuan; Wu, Hung-Yi
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This article is from Viruses , volume 6 . Abstract It has been demonstrated that, in addition to genomic RNA, sgmRNA is able to serve as a template for the synthesis of the negative-strand [(−)-strand] complement. However, the cis-acting elements on the positive-strand [(+)-strand] sgmRNA required for (−)-strand sgmRNA synthesis have not yet been systematically identified. In this study, we employed real-time quantitative reverse transcription polymerase chain reaction to analyze the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147681
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57
Oct 11, 2014
10/14
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Yasuda, Kei; Watkins, Amanda A.; Kochar, Guneet S.; Wilson, Gabriella E.; Laskow, Bari; Richez, Christophe; Bonegio, Ramon G.; Rifkin, Ian R.
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This article is from PLoS ONE , volume 9 . Abstract Interferon regulatory factor 5 (IRF5) polymorphisms are strongly associated with an increased risk of developing the autoimmune disease systemic lupus erythematosus. In mouse lupus models, IRF5-deficiency was shown to reduce disease severity consistent with an important role for IRF5 in disease pathogenesis. However these mouse studies were confounded by the recent demonstration that the IRF5 knockout mouse line contained a loss-of-function...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116215
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53
Oct 10, 2014
10/14
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Yao, Xuan; Hou, Sarina; Zhang, Duo; Xia, Hongfeng; Wang, Yu-Cheng; Jiang, Jingjing; Yin, Huiyong; Ying, Hao
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This article is from Cell & Bioscience , volume 4 . Abstract Background: Thyroid hormones (THs) are potent hormones modulating liver lipid homeostasis. The perturbation of lipid homeostasis is a hallmark of non-alcoholic fatty liver disease (NAFLD), a very common liver disorder. It was reported that NAFLD patients were associated with higher incidence of hypothyroidism. However, whether abnormal thyroid function contributes to the pathogenesis of NAFLD remains unclear. Results: We used in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124172
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6.0
Jun 30, 2018
06/18
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Yan-Lin Tang; Hua-Lei Yin; Si-Jing Chen; Yang Liu; Wei-Jun Zhang; Xiao Jiang; Lu Zhang; Jian Wang; Li-Xing You; Jian-Yu Guan; Dong-Xu Yang; Zhen Wang; Hao Liang; Zhen Zhang; Nan Zhou; Xiongfeng Ma; Teng-Yun Chen; Qiang Zhang; Jian-Wei Pan
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eye 6
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Measurement-device-independent quantum key distribution (MDIQKD) protocol is immune to all attacks on detection and guarantees the information-theoretical security even with imperfect single photon detectors. Recently, several proof-of-principle demonstrations of MDIQKD have been achieved. Those experiments, although novel, are implemented through limited distance with a key rate less than 0.1 bps. Here, by developing a 75 MHz clock rate fully-automatic and highly-stable system, and...
Topic: Quantum Physics
Source: http://arxiv.org/abs/1407.8012
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5.0
Jun 30, 2018
06/18
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Ya-feng He; Wei-hua Gong; Yong-liang Zhang; Fu-cheng Liu
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eye 5
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Hypocycloid and epicycloid motions of irregular grain (pine pollen) are observed for the first time in unmagnetized dust plasma in 2D horizontal plane. Hypocycloid motions occur both inside and outside the glass ring which confines the grain. Epicycloid motion only appears outside the glass ring. Cuspate cycloid motions, circle motion, and stationary grain are also observed. All these motions are related with both the initial conditions of dropped grain and the discharge parameters. The Magnus...
Topics: Physics, Plasma Physics
Source: http://arxiv.org/abs/1407.7962
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5.0
Jun 30, 2018
06/18
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Xiang Wan; Wenqian Wang; Jiming Liu; Tiejun Tong
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eye 5
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In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum and maximum values, and/or the first and third quartiles. Hence, in order to combine results, one may have to estimate the sample mean and standard deviation for such trials. In this paper, we propose to improve the existing literature in several directions....
Topics: Statistics, Methodology
Source: http://arxiv.org/abs/1407.8038
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65
Oct 13, 2014
10/14
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Wu, Zehong; Liu, Dong; Proksch, Peter; Guo, Peng; Lin, Wenhan
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This article is from Marine Drugs , volume 12 . Abstract Six new caryophyllene-based sesquiterpenoids named punctaporonins H–M (1–6), together with punctaporonin B (7) and humulane (8) were isolated from the fermentation broth of the sponge-derived fungus Hansfordia sinuosae. Their structures were determined by the extensive HRESIMS and NMR spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurations of punctaporonins H–I (1–2). The...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113805
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88
Oct 8, 2014
10/14
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Wu, Nan; Cai, Xiaoling; Ye, Kuanping; Li, Yintao; He, Min; Zhao, Weiwei; Hu, Renming
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This article is from Diabetology & Metabolic Syndrome , volume 6 . Abstract Background: Cardiac autonomic neuropathy (CAN) is a common complication of type 2 diabetes mellitus (T2DM). Brachial-ankle pulse wave velocity (baPWV) is known to be a good surrogate marker of vascular damages. The goal of this study was to investigate the relationship between BaPWV and CAN in T2DM. Methods: A total of 148 patients who had no apparent history of cardiovascular condition were enrolled consecutively...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132900
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60
Oct 11, 2014
10/14
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Won, Jong Chul; Park, Cheol-Young; Oh, Sang Woo; Lee, Eon Sook; Youn, Byung-Soo; Kim, Min-Seon
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eye 60
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This article is from PLoS ONE , volume 9 . Abstract Obesity and insulin resistance are hallmarks of the metabolic syndrome, which is associated with low-grade chronic inflammation. Clusterin/apolipoprotein J is an abundant plasma chaperone protein that has recently been suggested as a potential biomarker that reflects the inflammatory process in Alzheimer's disease. In the present study, we investigated anthropometric and clinical factors affecting the plasma levels of clusterin in healthy...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116172
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86
Oct 8, 2014
10/14
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Wilson, C. Brad; McLaughlin, Leslie D.; Ebenezer, Philip J.; Nair, Anand R.; Dange, Rahul; Harre, Joseph G.; Shaak, Thomas L.; Diamond, David M.; Francis, Joseph
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This article is from Frontiers in Behavioral Neuroscience , volume 8 . Abstract Serotonin (5-HT), norepinephrine (NE), and other neurotransmitters are modulated in post-traumatic stress disorder (PTSD). In addition, pro-inflammatory cytokines (PIC) are elevated during the progression of the disorder. Currently, the only approved pharmacologic treatments for PTSD are the selective-serotonin reuptake inhibitors (SSRI) sertraline and paroxetine, but their efficacy in treating PTSD is marginal at...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115632
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53
Oct 11, 2014
10/14
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Willcox, Merlin L.; Dicko, Moussa I.; Graz, Bertrand; Forster, Mathieu; Shinkins, Bethany; Diakite, Chiaka; Giani, Sergio; Falquet, Jacques; Diallo, Drissa; Dembele, Eugene
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This article is from PLoS ONE , volume 9 . Abstract Background: Inpatient case fatality from severe malaria remains high in much of sub-Saharan Africa. The majority of these deaths occur within 24 hours of admission, suggesting that pre-hospital management may have an impact on the risk of case fatality. Methods: Prospective cohort study, including questionnaire about pre-hospital treatment, of all 437 patients admitted with severe febrile illness (presumed to be severe malaria) to the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116122
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83
Oct 10, 2014
10/14
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Wheeler, Anne C; Bailey Jr, Donald B; Berry-Kravis, Elizabeth; Greenberg, Jan; Losh, Molly; Mailick, Marsha; Mila, Montserrat; Olichney, John M; Rodriguez-Revenga, Laia; Sherman, Stephanie; Smith, Leann; Summers, Scott; Yang, Jin-Chen; Hagerman, Randi
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This article is from Journal of Neurodevelopmental Disorders , volume 6 . Abstract Changes in the fragile X mental retardation 1 gene (FMR1) have been associated with specific phenotypes, most specifically those of fragile X syndrome (FXS), fragile X tremor/ataxia syndrome (FXTAS), and fragile X primary ovarian insufficiency (FXPOI). Evidence of increased risk for additional medical, psychiatric, and cognitive features and conditions is now known to exist for individuals with a premutation,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121434
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13
Jun 30, 2018
06/18
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Wee Liang Gan; Liping Li
texts
eye 13
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It is known that finitely generated FI-modules over a field of characteristic 0 are Noetherian. We generalize this result to the abstract setting of an infinite EI category satisfying certain combinatorial conditions.
Topics: Geometric Topology, Mathematics, Representation Theory, Commutative Algebra, Group Theory
Source: http://arxiv.org/abs/1407.8235
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68
Oct 11, 2014
10/14
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Webber, Amanda D.; Hill, Catherine M.
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This article is from PLoS ONE , volume 9 . Abstract Considering how people perceive risks to their livelihoods from local wildlife is central to (i) understanding the impact of crop damage by animals on local people and (ii) recognising how this influences their interactions with, and attitudes towards, wildlife. Participatory risk mapping (PRM) is a simple, analytical tool that can be used to identify and classify risk within communities. Here we use it to explore local people's perceptions of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116180
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5.0
Jun 30, 2018
06/18
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Wang Cong; Jaume Llibre; Xiang Zhang
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eye 5
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In this paper we mainly study the necessary conditions for the existence of functionally independent generalized rational first integrals of ordinary differential systems via the resonances. The main results extend some of the previous related ones, for instance the classical Poincar\'e's one \cite{Po}, the Furta's one, part of Chen's ones, and the Shi's one. The key point in the proof of our main results is that functionally independence of generalized rational functions implies the...
Topics: Mathematics, Classical Analysis and ODEs, Dynamical Systems
Source: http://arxiv.org/abs/1407.7948
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73
Oct 14, 2014
10/14
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Wanda, Franck; Nkemenang, Patrick; Ehounou, Genevieve; Tchaton, Marie; Comte, Eric; Toutous Trellu, Laurence; Masouye, Isabelle; Christinet, Vanessa; O'Brien, Daniel P
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This article is from BMC Infectious Diseases , volume 14 . Abstract Background: In West and Central Africa Buruli ulcer (BU) and HIV co-infection is increasingly recognised and management of these two diseases combined is an emerging challenge for which there is little published information. In this case we present a severe paradoxical reaction occurring after commencing antibiotic treatment for BU combined with antiretroviral therapy for HIV, and describe its clinical features and management....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122778
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6.0
Jun 30, 2018
06/18
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Wan-Li Ju; Guo-Li Wang; Hui-Feng Fu; Zhi-Hui Wang; Ying Li
texts
eye 6
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The rare processes $B_c\to D_{(s)J} ^{(*)}\mu\bar{\mu}$, where $D_{(s)J}^{(*)}$ stands for the final meson $D_{s0}^*(2317)$, $D_{s1}(2460,2536)$,~$D_{s2}^*(2573)$, $D_0^*(2400)$, $D_{1}(2420,2430)$ or~$D_{2}^*(2460)$, are studied within the Standard Model. The hadronic matrix elements are evaluated in the Bethe-Salpeter approach and furthermore a discussion on the gauge-invariant condition of the annihilation hadronic currents is presented. Considering the penguin, box, annihilation,...
Topic: High Energy Physics - Phenomenology
Source: http://arxiv.org/abs/1407.7968
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134
Oct 10, 2014
10/14
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Tolsgaard, Martin G; Ku, Cheryl; Woods, Nicole N; Kulasegaram, Kulamakan Mahan; Brydges, Ryan; Ringsted, Charlotte
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This article is from BMJ Open , volume 4 . Abstract Introduction: Research in medical education has increased in volume over the past decades but concerns have been raised regarding the quality of trials conducted within this field. Randomised controlled trials (RCTs) involving educational interventions that are reported in biomedical journals have been criticised for their insufficient conceptual, theoretical framework. RCTs published in journals dedicated to medical education, on the other...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120313
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103
Oct 10, 2014
10/14
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Timm, Richard W; Asher, Ryan M; Tellio, Karalyn R; Welling, Alissa L; Clymer, Jeffrey W; Amaral, Joseph F
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This article is from Medical Devices (Auckland, N.Z.) , volume 7 . Abstract Introduction: Ultrasonic energy is a mainstay in the armamentarium of surgeons, providing multifunctionality, precision, and control when dissecting and sealing vessels up to 5 mm in diameter. Historically, the inability to seal vessels in the 5–7 mm range has been perceived as an inherent limitation of ultrasonic technology. The purpose of this study was to evaluate sealing of vessels up to 7 mm in diameter with an...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124047
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3.0
Jun 30, 2018
06/18
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Th. Rivinius; W. J. de Wit; Z. Demers; A. Quirrenbach; the VLTI Science Operations Team
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OHANA is an interferometric snapshot survey of the gaseous circumstellar environments of hot stars, carried out by the VLTI group at the Paranal observatory. It aims to characterize the mass-loss dynamics (winds/disks) at unexplored spatial scales for many stars. The survey employs the unique combination of AMBER's high spectral resolution with the unmatched spatial resolution provided by the VLTI. Because of the spatially unresolved central OBA-type star, with roughly neutral colour terms,...
Topics: Astrophysics, Solar and Stellar Astrophysics
Source: http://arxiv.org/abs/1407.8135
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50
Oct 10, 2014
10/14
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Tao, Chuan-yuan; Wang, Jia-jing; Li, Hao; You, Chao
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This article is from World Journal of Surgical Oncology , volume 12 . Abstract Background: Malignant intraventricular meningiomas are quite rare and may spread along the craniospinal axis or extraneurally. However, simultaneous cerebrospinal dissemination and distal extraneural metastasis has seldom been reported. Case presentation: A 51-year-old woman presented with recurrent anaplastic meningioma in the trigone of right lateral ventricle over a 1.5-year period. Suggested radiotherapy was...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126346
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92
Oct 8, 2014
10/14
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Soysa, Preethi; De Silva, Irushi Shamalika; Wijayabandara, Jayantha
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This article is from BMC Complementary and Alternative Medicine , volume 14 . Abstract Background: Flueggea leucopyrus Willd is a shrub grown in many parts of the dry zones in Sri Lanka. The leaves of F. leucopyrus has been used for treating cancer in the traditional system of medicine in Sri Lanka. Hence, this study was performed to analyze the antioxidant and antiproliferative properties of the aqueous extract of the leaves of F. leucopyrus on HEp-2 cells. Method: The aqueous extract of F....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129101
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51
Oct 5, 2014
10/14
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Smith, Morgan B.; Griffiths, Elizabeth A.; Thompson, James E.; Wang, Eunice S.; Wetzler, Meir; Freyer, Craig W.
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This article is from Leukemia Research Reports , volume 3 . Abstract Dual differentiation therapy with arsenic trioxide and tretinoin (all-trans-retinoic acid; ATRA) for the management of low and intermediate risk acute promyelocytic leukemia has recently been recommended by the National Comprehensive Cancer Network. Some less common toxicities of the combination may have yet to be fully realized. Of ten patients we have treated thus far, five (50%) have developed pseudotumor cerebri. In one...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145165
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83
Oct 9, 2014
10/14
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Seo, Mi-Ran; Kim, Seong-Jong; Kim, Yeonjae; Kim, Jieun; Choi, Tae Yeal; Kang, Jung Oak; Wie, Seong-Heon; Ki, Moran; Cho, Young Kyun; Lim, Seung-Kwan; Lee, Jin Seo; Kwon, Ki Tae; Lee, Hyuck; Cheong, Hee Jin; Park, Dae Won; Ryu, Seong Yeol; Chung, Moon-Hyun; Pai, Hyunjoo
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This article is from Journal of Korean Medical Science , volume 29 . Abstract With increase of multi-drug resistant Escherichia coli in community-acquired urinary tract infections (CA-UTI), other treatment option with a therapeutic efficacy and a low antibiotic selective pressure is necessary. In this study, we evaluated in vitro susceptibility of E. coli isolates from CA-UTI to fosfomycin (FM), nitrofurantoin (NI), temocillin (TMO) as well as trimethoprim-sulfamethoxazole (SMX), ciprofloxacin...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129215
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51
Oct 11, 2014
10/14
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Santos, Maria Joao; Watt, Terry; Pincetl, Stephanie
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This article is from PLoS ONE , volume 9 . Abstract The growth of human populations and their resource needs have stressed the conservation of natural land resources. Many policies and programs have been implemented to address the pressures on land resources and notwithstanding this pressure, significant acquisition of land for conservation has occurred throughout history in the U.S., and internationally. Here we assess the on-the-ground result of the evolution of land use policies in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116213
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102
Oct 3, 2014
10/14
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Sakai, Ryo; Winand, Raf; Verbeiren, Toni; Moere, Andrew Vande; Aerts, Jan
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This article is from F1000Research , volume 3 . Abstract Dendrograms are graphical representations of binary tree structures resulting from agglomerative hierarchical clustering. In Life Science, a cluster heat map is a widely accepted visualization technique that utilizes the leaf order of a dendrogram to reorder the rows and columns of the data table. The derived linear order is more meaningful than a random order, because it groups similar items together. However, two consecutive items...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162509
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4.0
Jun 30, 2018
06/18
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S. Ehlert; S. W. Allen; W. N. Brandt; R. E. A. Canning; B. Luo; A. Mantz; R. G. Morris; A. von der Linden; Y. Q. Xue
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We present the results of a new analysis of the X-ray selected Active Galactic Nuclei (AGN) population in the vicinity of 135 of the most massive galaxy clusters in the redshift range of 0.2 < z < 0.9 observed with Chandra. With a sample of more than 11,000 X-ray point sources, we are able to measure, for the first time, evidence for evolution in the cluster AGN population beyond the expected evolution of field AGN. Our analysis shows that overall number density of cluster AGN scales with...
Topics: Astrophysics of Galaxies, Astrophysics, Cosmology and Nongalactic Astrophysics
Source: http://arxiv.org/abs/1407.8181
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4.0
Jun 30, 2018
06/18
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Rosalie McGurk; Constance Rockosi; Donald Gavel; Renate Kupke; Michael Peck; Terry Pfister; Jim Ward; William Deich; John Gates; Elinor Gates; Barry Alcott; David Cowley; Daren Dillon; Kyle Lanclos; Dale Sandford; Mike Saylor; Srikar Srinath; Jason Weiss; Andrew Norton
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We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable of high-efficiency, diffraction-limited imaging and low-dispersion grism spectroscopy in J, H, and K-bands. ShARCS uses a HAWAII-2RG infrared detector, giving high quantum efficiency (>80%) and Nyquist sampling the diffraction limit in all...
Topics: Instrumentation and Methods for Astrophysics, Astrophysics
Source: http://arxiv.org/abs/1407.8205
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60
Oct 11, 2014
10/14
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Roozendaal, Ramon; Tolboom, Jeroen; Roos, Anna; Riahi, Sarra; Theeuwsen, Jessica; Bujny, Miriam V.; Klaren, Vincent; Korse, Hans J. W. M.; Dekking, Liesbeth; Grootenhuis, Arijan; Weverling, Gerrit Jan; Koudstaal, Wouter; Goudsmit, Jaap; Radosevic, Katarina
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This article is from PLoS ONE , volume 9 . Abstract Current influenza vaccines are believed to confer protection against a narrow range of virus strains. The identification of broadly influenza neutralizing antibodies (bnAbs) has triggered efforts to develop vaccines providing ‘universal’ protection against influenza. Several bnAbs were isolated from humans recently vaccinated with conventional influenza vaccines, suggesting that such vaccines could, in principle, be broadly protective....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116209
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Oct 11, 2014
10/14
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Regan, Fran H.; Hockenhull, Jo; Pritchard, Joy C.; Waterman-Pearson, Avril E.; Whay, Helen R.
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This article is from PLoS ONE , volume 9 . Abstract Background: The donkey has a reputation for stoicism and its behavioural repertoire in clinical contexts is under-reported. Lack of understanding of the norms of donkey behaviour and how it may vary over time can compromise use of behavioural measures as indicators of pain or emotional state. The objective of this study was to find out whether the behaviour of working donkeys was influenced by gender, the time of day or differed between days...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116118
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18
Oct 3, 2014
10/14
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Peffers, Mandy J.; Thorpe, Chavaunne T.; Collins, John A.; Eong, Robin; Wei, Timothy K. J.; Screen, Hazel R. C.; Clegg, Peter D.
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eye 18
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This article is from The Journal of Biological Chemistry , volume 289 . Abstract Background: Alterations in tendon matrix composition with aging and injury are poorly understood.Results: Aging and injury resulted in distinct protein profiles, with age-specific peptide fragmentation in injury.Conclusion: Identification of protein cleavages associated with aging and injury suggest impaired maintenance and repair in aged tendon.Significance: Novel peptide fragments identified are potential...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162187
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19
Oct 5, 2014
10/14
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Obaid, Sami; Li, Shu; Denis, Daniel; Weil, Alexander G.; Bojanowski, Michel W.
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eye 19
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This article is from Surgical Neurology International , volume 5 . Abstract Background:: Cavernous angiomas (CAs) of cranial nerves are rare, and their occurrence on the third cranial nerve is particularly rare. Surgical management of such CAs involving the third nerve is controversial. We describe a case of a symptomatic CA of the oculomotor nerve and review the literature in order to ascertain the relevance of surgical intervention. Case Description:: A 71-year-old male patient presented with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138817
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44
Oct 10, 2014
10/14
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Nygardh, Annette; Malm, Dan; Wikby, Kerstin; Ahlstrom, Gerd
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This article is from BMC Nursing , volume 13 . Abstract Background: This study is part of an interactive improvement intervention aimed to facilitate empowerment-based chronic kidney care using data from persons with CKD and their family members. There are many challenges to implementing empowerment-based care, and it is therefore necessary to study the implementation process. The aim of this study was to generate knowledge regarding the implementation process of an improvement intervention of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124497
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Oct 3, 2014
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Nombela, Cristina; Rowe, James B.; Winder-Rhodes, Sophie E.; Hampshire, Adam; Owen, Adrian M.; Breen, David P.; Duncan, Gordon W.; Khoo, Tien K.; Yarnall, Alison J.; Firbank, Michael J.; Chinnery, Patrick F.; Robbins, Trevor W.; O'Brien, John T.; Brooks, David J.; Burn, David J.; Barker, Roger A.
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This article is from Brain , volume 137 . Abstract See Dujardin (doi:10.1093/brain/awu218) for a scientific commentary on this article. Nombela et al. present data from the ICICLE-PD study of cognition in newly diagnosed Parkinson’s disease. Consistent with the ‘Dual Syndrome’ hypothesis, impairments in executive function reflect a frontal dopaminergic syndrome modulated by COMT genotype, while visuospatial and memory deficits reflect disruption of temporo-parietal systems modulated by...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163033
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65
Oct 11, 2014
10/14
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Ning, Shangwei; Zhao, Zuxianglan; Ye, Jingrun; Wang, Peng; Zhi, Hui; Li, Ronghong; Wang, Tingting; Wang, Jianjian; Wang, Lihua; Li, Xia
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This article is from PLoS ONE , volume 9 . Abstract Large intergenic non-coding RNAs (lincRNAs) are a new class of functional transcripts, and aberrant expression of lincRNAs was associated with several human diseases. The genetic variants in lincRNA transcription factor binding sites (TFBSs) can change lincRNA expression, thereby affecting the susceptibility to human diseases. To identify and annotate these functional candidates, we have developed a database SNP@lincTFBS, which is devoted to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116217
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20
Oct 5, 2014
10/14
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Nelson, Heidi D.; Weerasinghe, Roshanthi; Martel, Maritza; Bifulco, Carlo; Assur, Ted; Elmore, Joann G.; Weaver, Donald L.
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This article is from Journal of Pathology Informatics , volume 5 . Abstract Background:: Health care systems rely on electronic patient data, yet access to breast tissue pathology results continues to depend on interpreting dictated free-text reports. Objective:: The objective was to develop a method to electronically search and categorize pathologic diagnoses of patients’ breast tissue specimens from dictated free-text pathology reports in a large health system for multiple users including...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141424
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Oct 6, 2014
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Nakamura, Kazufumi; Oe, Hiroki; Kihara, Hajime; Shimada, Kenei; Fukuda, Shota; Watanabe, Kyoko; Takagi, Tsutomu; Yunoki, Kei; Miyoshi, Toru; Hirata, Kumiko; Yoshikawa, Junichi; Ito, Hiroshi
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This article is from Cardiovascular Diabetology , volume 13 . Abstract Background: Alpha glucosidase inhibitor (GI) attenuates postprandial hyperglycemia (PPH) and reduces the risk of cardiovascular events in patients with impaired glucose tolerance or type 2 diabetes. Dipeptidyl peptidase 4 (DPP-4) inhibitors also attenuate PPH. PPH is one of the factors leading to endothelial dysfunction which is an early event in the pathogenesis of atherosclerosis. Furthermore, DPP-4 inhibitors protect...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149239
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Oct 8, 2014
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Mundalil Vasu, Mahesh; Anitha, Ayyappan; Thanseem, Ismail; Suzuki, Katsuaki; Yamada, Kohei; Takahashi, Taro; Wakuda, Tomoyasu; Iwata, Keiko; Tsujii, Masatsugu; Sugiyama, Toshirou; Mori, Norio
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This article is from Molecular Autism , volume 5 . Abstract Background: As regulators of gene expression, microRNAs (miRNAs) play a key role in the transcriptional networks of the developing human brain. Circulating miRNAs in the serum and plasma are remarkably stable and are suggested to have promise as noninvasive biomarkers for neurological and neurodevelopmental disorders. We examined the serum expression profiles of neurologically relevant miRNAs in autism spectrum disorder (ASD), a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132421
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Oct 11, 2014
10/14
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Mullen, John C; Kuurstra, Emily J; Oreopoulos, Antigone; Bentley, Michael J; Wang, Shaohua
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This article is from Transplantation Research , volume 3 . Abstract Background: The purpose of this study was to test the efficacy and safety of daclizumab (DZM) versus anti-thymocyte globulin (ATG) as a component of induction therapy in heart transplant recipients. Methods: Thirty heart transplant patients were randomized to receive either ATG or DZM during induction therapy. Patients in the DZM group received an initial dose of 2 mg/kg intravenous (IV) at the time of transplant and 1 mg/kg IV...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120716
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Jun 30, 2018
06/18
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M. L. Parker; D. R. Wilkins; A. C. Fabian; D. Grupe; T. Dauser; G. Matt; F. A. Harrison; L. Brenneman; S. E. Boggs; F. E. Christensen; W. W. Craig; L. C. Gallo; C. J. Hailey; E. Kara; S. Komossa; A. Marinucci; J. M. Miller; G. Risaliti; D. Stern; D. J. Walton; W. W. Zhang
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We present 3-50 keV NuSTAR observations of the AGN Mrk 335 in a very low flux state. The spectrum is dominated by very strong features at the energies of the iron line at 5-7 keV and Compton hump from 10-30 keV. The source is variable during the observation, with the variability concentrated at low energies, which suggesting either a relativistic reflection or a variable absorption scenario. In this work we focus on the reflection interpretation, making use of new relativistic reflection models...
Topics: High Energy Astrophysical Phenomena, Astrophysics
Source: http://arxiv.org/abs/1407.8223
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Jun 30, 2018
06/18
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Luis A. Anchordoqui; Ignatios Antoniadis; De-Chang Dai; Wan-Zhe Feng; Haim Goldberg; Xing Huang; Dieter Lust; Dejan Stojkovic; Tomasz R. Taylor
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[Abridged] We consider extensions of the standard model based on open strings ending on D-branes. Assuming that the fundamental string mass scale M_s is in the TeV range and that the theory is weakly coupled, we discuss possible signals of string physics at the upcoming HL-LHC run (3000 fb^{-1}) with \sqrt{s} = 14 TeV, and at potential future pp colliders, HE-LHC and VLHC, operating at \sqrt{s} = 33 and 100 TeV, respectively. In such D-brane constructions, the dominant contributions to...
Topics: High Energy Physics - Theory, High Energy Physics - Phenomenology
Source: http://arxiv.org/abs/1407.8120
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Oct 12, 2014
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Liu, Yi-Nan; Yan, Yan; Li, Shi-Jie; Liu, Hui; Wu, Qi; Zhang, Li-Jian; Yang, Yue; Chen, Jin-Feng
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This article is from World Journal of Surgical Oncology , volume 12 . Abstract Background: A gastroesophageal anastomotic fistula remains a potentially life-threatening post-esophagectomy complication. To promote fistula closure, we developed a modified endoscopic method of trans-fistula drainage with persistent negative pressure. In this study, we aimed to evaluate the efficacy of this endoscopic therapy. Methods: Between June and November 2013, five male patients with post-surgical esophageal...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119058
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Oct 11, 2014
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Li, Jin Hua; Yang, Yu Jie; Li, Bo Wen; Li, Wen Jin; Wang, Gang; Knops, Johannes M. H.
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This article is from PLoS ONE , volume 9 . Abstract In grassland ecosystems, N and P fertilization often increase plant productivity, but there is no concensus if fertilization affects soil C fractions. We tested effects of N, P and N+P fertilization at 5, 10, 15 g m−2 yr−1 (N5, N10, N15, P5, P10, P15, N5P5, N10P10, and N15P15) compared to unfertilized control on soil C, soil microbial biomass and functional diversity at the 0–20 cm and 20–40 cm depth in an alpine meadow after 5 years...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116255
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Oct 4, 2014
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LI, GUO-CAI; XU, YONG; ZHANG, YU-CHUN; ZHANG, FANG-CHENG; WANG, QI; MA, QING-JIU
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This article is from Oncology Letters , volume 8 . Abstract Surgery for digestive tract disease predominantly consists of reconstruction and anastomosis. Due to the difficult location, anastomosis is extremely challenging and the risk of complication increases accordingly. Traditional manual anastomosis and the application of a stapling device are insufficient. Therefore, the aim of this study was to investigate the feasibility and safety of a novel manual method in a difficult anastomotic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156267
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Jun 30, 2018
06/18
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LHCb collaboration; R. Aaij; B. Adeva; M. Adinolfi; A. Affolder; Z. Ajaltouni; S. Akar; J. Albrecht; F. Alessio; M. Alexander; S. Ali; K. Carvalho Akiba; G. Casse; L. Cassina; L. Castillo Garcia; M. Cattaneo; Ch. Cauet; R. Cenci; M. Charles; Ph. Charpentier; S. Chen; G. Alkhazov; S. -F. Cheung; N. Chiapolini; M. Chrzaszcz; K. Ciba; X. Cid Vidal; G. Ciezarek; P. E. L. Clarke; M. Clemencic; H. V. Cliff; J. Closier; P. Alvarez Cartelle; V. Coco; J. Cogan; E. Cogneras; P. Collins; A....
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An analysis of B0->D K*0 decays is presented, where D represents an admixture of D0 and D0b mesons reconstructed in four separate final states: K-pi+, pi-K+, K+K- and pi+pi-. The data sample corresponds to 3.0fb-1 of proton-proton collision, collected by the LHCb experiment. Measurements of several observables are performed, including CP asymmetries. The most precise determination is presented of rB(DK*0), the magnitude of the ratio of the amplitudes of the decay B0->D K+ pi- with a...
Topic: High Energy Physics - Experiment
Source: http://arxiv.org/abs/1407.8136
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Oct 9, 2014
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Kwon, Jeanny; Chie, Eui Kyu; Kim, Kyubo; Kim, Hak Jae; Wu, Hong-Gyun; Kim, Il Han; Oh, Do-Youn; Lee, Se-Hoon; Kim, Dong-Wan; Im, Seock-Ah; Kim, Tae-You; Heo, Dae-Seog; Bang, Yung-Jue; Ha, Sung W.
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This article is from Journal of Korean Medical Science , volume 29 . Abstract The purpose of this study was to evaluate treatment patterns, outcome and prognosticators for patients with leptomeningeal metastases from solid tumor. Medical records of 80 patients from January 1, 2004 to May 31, 2011 were retrospectively reviewed. Most frequent site of origin was the lung (59%) followed by the breast (25%). Most patients were treated with intrathecal chemotherapy (90%) and/or whole brain...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129201
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Oct 11, 2014
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Kivisakk, Pia; Francois, Katiana; Mbianda, Julvet; Gandhi, Roopali; Weiner, Howard L.; Khoury, Samia J.
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This article is from PLoS ONE , volume 9 . Abstract Objectives: Dendritic cells (DCs) serve a critical role both in promoting and inhibiting adaptive immunity. The goal of this study was to investigate the effect of natalizumab (NTZ) treatment on DC numbers, phenotype, and function in patients with multiple sclerosis (MS). Methods: Frequency and phenotype of myeloid and plasmacytoid DCs (MDCs and PDCs, respectively) were analyzed in blood from two separate cohorts of untreated,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116240
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Oct 2, 2014
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Kim, Sung-Hee; Gerver, Sarah M.; Fidler, Sarah; Ward, Helen
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This article is from AIDS (London, England) , volume 28 . Abstract Objective:: Adolescent and young adult (AYA) populations (12–24 years) represent over 40% of new HIV infections globally. Adolescence is sometimes characterized by high-risk sexual behaviour and a lack of engagement with healthcare services that can affect adherence to antiretroviral therapy (ART). Despite adherence to ART being critical in controlling viral replication, maintaining health and reducing onward viral...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162330
