9
9.0
Jun 8, 2021
06/21
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Customized version of http://www.thingiverse.com/thing:74322 Created with Customizer! http://www.thingiverse.com/apps/customizer/run?thing_id=74322
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9
9.0
Jun 6, 2021
06/21
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(pictux)
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eye 9
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Customized version of http://www.thingiverse.com/thing:52734 Created with Customizer! http://www.thingiverse.com/apps/customizer/run?thing_id=52734
Topics: customized, stl, Organization, thingiverse
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Oct 23, 2014
10/14
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Bauza, Karolis; Malinauskas, Tomas; Pfander, Claudia; Anar, Burcu; Jones, E. Yvonne; Billker, Oliver; Hill, Adrian V. S.; Reyes-Sandoval, Arturo
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eye 46
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This article is from Infection and Immunity , volume 82 . Abstract Plasmodium vivax is the world's most widely distributed malaria parasite and a potential cause of morbidity and mortality for approximately 2.85 billion people living mainly in Southeast Asia and Latin America. Despite this dramatic burden, very few vaccines have been assessed in humans. The clinically relevant vectors modified vaccinia virus Ankara (MVA) and the chimpanzee adenovirus ChAd63 are promising delivery systems for...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957994
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79
Oct 21, 2014
10/14
by
Bechir, Markus; Puhan, Milo A; Fasshauer, Mario; Schuepbach, Reto A; Stocker, Reto; Neff, Thomas A
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eye 79
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This article is from Critical Care , volume 17 . Abstract Introduction: There are limited data on the efficacy of early fluid resuscitation with third-generation hydroxyethyl starch (HES 130) in burn injury. Adverse effects of HES on survival and organ function have been reported. Methods: In this randomized, controlled, double-blind trial, 48 patients with severe burn injury were assigned to receive either lactated Ringer’s solution plus 6% HES 130/0.4 in a ratio of 2:1 or lactated...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057504
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70
Oct 23, 2014
10/14
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Behzad, Sahar; Pirani, Atefeh; Mosaddegh, Mahmoud
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This article is from Iranian Journal of Pharmaceutical Research : IJPR , volume 13 . Abstract Medicinal plants have been investigated for possible anti-cancer effects. The aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of Hamedan district of Iran. The methanolic extracts of the plants were prepared and their...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977071
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41
Oct 24, 2014
10/14
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Blazevic, Tina; Schaible, Anja M.; Weinhaupl, Katharina; Schachner, Daniel; Nikels, Felix; Weinigel, Christina; Barz, Dagmar; Atanasov, Atanas G.; Pergola, Carlo; Werz, Oliver; Dirsch, Verena M.; Heiss, Elke H.
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This article is from Cardiovascular Research , volume 101 . Abstract Aims: The small molecule indirubin-3′-monoxime (I3MO) has been shown to inhibit vascular smooth muscle cell (VSMC) proliferation and neointima formation in vivo. The influence of I3MO on VSMC migration and vascular inflammation, two additional key players during the onset of atherosclerosis and restenosis, should be investigated. Methods and results: We examined the influence of I3MO on VSMC migration, with focus on...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928003
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57
Oct 27, 2014
10/14
by
Carlini, Federico; Traore, Karim; Cherouat, Nissem; Roubertoux, Pierre; Buhler, Stephane; Cortey, Marti; Simon, Sophie; Doumbo, Ogobara; Chiaroni, Jacques; Picard, Christophe; Di Cristofaro, Julie
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eye 57
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This article is from PLoS ONE , volume 8 . Abstract The HLA-G molecule plays an important role in immunomodulation. In a previous study carried out on a southern French population our team showed that HLA-G haplotypes, defined by SNPs in the coding region and specific SNPs located in 5′URR and 3′UTR regulatory regions, are associated with differential soluble HLA-G expression (sHLA-G). Furthermore, the structure of these HLA-G haplotypes appears to be conserved in geographically distant...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871591
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Oct 28, 2014
10/14
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Carnie, A; Lin, J; Aicher, B; Leon, B; Courville, A B; Sebring, N G; de Jesus, J; DellaValle, D M; Fitzpatrick, B D; Zalos, G; Powell-Wiley, T M; Chen, K Y; Cannon, R O
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This article is from Nutrition & Diabetes , volume 3 . Abstract Objective:: Obesity in the United States is highly prevalent, approaching 60% for black women. We investigated whether nutrition education sessions at the work place added to internet-based wellness information and exercise resources would facilitate weight and fat mass loss in a racially diverse population of overweight female employees. Methods:: A total of 199 (average body mass index 33.9±6.3 kg m−2) nondiabetic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877430
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Oct 28, 2014
10/14
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Choulagai, Bishnu; Onta, Sharad; Subedi, Narayan; Mehata, Suresh; Bhandari, Gajananda P; Poudyal, Amod; Shrestha, Binjwala; Mathai, Matthews; Petzold, Max; Krettek, Alexandra
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This article is from BMC International Health and Human Rights , volume 13 . Abstract Background: Skilled birth attendants (SBAs) provide important interventions that improve maternal and neonatal health and reduce maternal and neonatal mortality. However, utilization and coverage of services by SBAs remain poor, especially in rural and remote areas of Nepal. This study examined the characteristics associated with utilization of SBA services in mid- and far-western Nepal. Methods: This...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878020
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47
Oct 23, 2014
10/14
by
Cooper, Lori A; Page, Stephanie T
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eye 47
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This article is from Asian Journal of Andrology , volume 16 . Abstract A growing body of literature has established the anabolic benefits of testosterone (T) therapy in hypogonadal men. However, there remains a paucity of data regarding the risks of exogenous androgen use in older men and the potential for adverse effects on the prostate gland. Whether T therapy in older, hypogonadal men might worsen lower urinary tract symptoms or exacerbate, unmask, or even incite prostate cancer development...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955334
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Oct 28, 2014
10/14
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Deja, Stanislaw; Dawiskiba, Tomasz; Balcerzak, Waldemar; Orczyk-Pawilowicz, Magdalena; Glod, Mateusz; Pawelka, Dorota; Mlynarz, Piotr
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eye 53
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This article is from PLoS ONE , volume 8 . Abstract Thyroid cancer is the most common endocrine malignancy. However, more than 90% of thyroid nodules are benign. It remains unclear whether thyroid carcinoma arises from preexisting benign nodules. Metabolomics can provide valuable and comprehensive information about low molecular weight compounds present in living systems and further our understanding of the biology regulating pathological processes. Herein, we applied 1H NMR-based metabolic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871661
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62
Oct 24, 2014
10/14
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Denkinger, Claudia M.; Kalantri, Yatiraj; Schumacher, Samuel G.; Michael, Joy S.; Shankar, Deepa; Saxena, Arvind; Sriram, Natarajan; Balamugesh, Thangakunam; Luo, Robert; Pollock, Nira R.; Pai, Madhukar; Christopher, Devasahayam J.
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This article is from PLoS ONE , volume 8 . Abstract Existing diagnostic tests for pleural tuberculosis (TB) have inadequate accuracy and/or turnaround time. Interferon-gamma (IFNg) has been identified in many studies as a biomarker for pleural TB. Our objective was to develop a lateral flow, immunochromatographic test (ICT) based on this biomarker and to evaluate the test in a clinical cohort. Because IFNg is commonly present in non-TB pleural effusions in low amounts, a diagnostic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871622
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Oct 24, 2014
10/14
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Driesen, Ronald B.; Nagaraju, Chandan K.; Abi-Char, Joelle; Coenen, Tamara; Lijnen, Paul J.; Fagard, Robert H.; Sipido, Karin R.; Petrov, Victor V.
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eye 46
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This article is from Cardiovascular Research , volume 101 . Abstract Aims: Differentiation of cardiac fibroblasts (Fbs) into myofibroblasts (MyoFbs) is responsible for connective tissue build-up in myocardial remodelling. We examined MyoFb differentiation and reversibility. Methods and results: Adult rat cardiac Fbs were cultured on a plastic substratum providing mechanical stress, with conditions to obtain different levels of Fb differentiation. Fb spontaneously differentiated to proliferating...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928002
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44
Oct 27, 2014
10/14
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Duran, Andressa; Meyer, Andreas L. S.; Pie, Marcio R.
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eye 44
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This article is from PLoS ONE , volume 8 . Abstract Despite considerable interest in recent years on species distribution modeling and phylogenetic niche conservatism, little is known about the way in which climatic niches change over evolutionary time. This knowledge is of major importance to understand the mechanisms underlying limits of species distributions, as well as to infer how different lineages might be affected by anthropogenic climate change. In this study we investigate the tempo...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871682
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Oct 26, 2014
10/14
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Farshid, Ahmad; Pathak, Rajeev; Shadbolt, Bruce; Arnolda, Leonard; Talaulikar, Girish
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eye 61
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This article is from BMC Nephrology , volume 14 . Abstract Background: Cardiovascular disease is a major cause of death in patients with stage 4–5 Chronic Kidney disease (CKD, eGFR 75 years, previous history of MI, diastolic dysfunction and detectable serum troponin T were significant independent predictor of mortality (P 75 years, history of MI, diastolic dysfunction and troponin T were independent predictors of mortality.
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878021
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Oct 23, 2014
10/14
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Flynn, Tanya J; Phipps-Green, Amanda; Hollis-Moffatt, Jade E; Merriman, Marilyn E; Topless, Ruth; Montgomery, Grant; Chapman, Brett; Stamp, Lisa K; Dalbeth, Nicola; Merriman, Tony R
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eye 63
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This article is from Arthritis Research & Therapy , volume 15 . Abstract Introduction: There is inconsistent association between urate transporters SLC22A11 (organic anion transporter 4 (OAT4)) and SLC22A12 (urate transporter 1 (URAT1)) and risk of gout. New Zealand (NZ) Māori and Pacific Island people have higher serum urate and more severe gout than European people. The aim of this study was to test genetic variation across the SLC22A11/SLC22A12 locus for association with risk of gout in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978909
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46
Oct 28, 2014
10/14
by
Frith, Jessica E.; Titmarsh, Drew M.; Padmanabhan, Harish; Cooper-White, Justin J.
texts
eye 46
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This article is from PLoS ONE , volume 8 . Abstract Cellular microenvironmental conditions coordinate to regulate stem cell populations and their differentiation. Mesenchymal precursor cells (MPCs), which have significant potential for a wide range of therapeutic applications, can be expanded or differentiated into osteo- chondro- and adipogenic lineages. The ability to establish, screen, and control aspects of the microenvironment is paramount if we are to elucidate the complex interplay of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871528
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52
Oct 25, 2014
10/14
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Glover, Marewa; Bosman, Amber; Wagemakers, Annemarie; Kira, Anette; Paton, Chris; Cowie, Nathan
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eye 52
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This article is from BMC Public Health , volume 13 . Abstract Background: Māori and Pacific Island people have significantly higher smoking rates compared to the rest of the New Zealand population. The main aim of this paper is to describe how knowledge of Indigenous people’s practices and principles can be combined with proven effective smoking cessation support into a cessation intervention appropriate for Indigenous people. Methods/Design: A literature review was conducted to identify...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882284
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47
Oct 27, 2014
10/14
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Guwatudde, David; Bwanga, Freddie; Dudley, Lilian; Chola, Lumbwe; Leyna, Germana Henry; Mmbaga, Elia John; Kumwenda, Newton; Protsiv, Myroslava; Atkins, Salla; Zwarenstein, Merrick; Obua, Celestino; Tumwine, James K
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eye 47
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This article is from Human Resources for Health , volume 11 . Abstract Background: The need to develop capacity for health services and systems research (HSSR) in low and middle income countries has been highlighted in a number of international forums. However, little is known about the level of HSSR training in Sub-Saharan Africa (SSA). We conducted an assessment at four major East and Southern African universities to describe: a) the numbers of HSSR PhD trainees at these institutions, b)...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878024
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Oct 27, 2014
10/14
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Hampton, David W; Serio, Andrea; Pryce, Gareth; Al-Izki, Sarah; Franklin, Robin JM; Giovannoni, Gavin; Baker, David; Chandran, Siddharthan
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eye 44
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This article is from Acta Neuropathologica Communications , volume 1 . Abstract Backgound: Multiple Sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives the relapse-remitting stage and neurodegeneration represents the principal substrate of secondary progression. In contrast to the increasing number of effective anti-inflammatory disease modifying treatments for relapse-remitting disease, the absence of therapies for...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895761
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76
Oct 20, 2014
10/14
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Hay, Debbie L; Harris, Paul WR; Kowalczyk, Renata; Brimble, Margaret A; Rathbone, Dan L; Barwell, James; Conner, Alex C; Poyner, David R
texts
eye 76
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This article is from British Journal of Pharmacology , volume 171 . Abstract Background and Purpose: The N-terminus of calcitonin gene-related peptide (CGRP) is important for receptor activation, especially the disulphide-bonded ring (residues 1–7). However, the roles of individual amino acids within this region have not been examined and so the molecular determinants of agonism are unknown. This study has examined the role of residues 1, 3–6 and 8–9, excluding Cys-2 and...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904261
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57
Oct 27, 2014
10/14
by
Hedrich, Christian M; Hofmann, Sigrun R; Pablik, Jessica; Morbach, Henner; Girschick, Hermann J
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eye 57
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This article is from Pediatric Rheumatology Online Journal , volume 11 . Abstract Sterile bone inflammation is the hallmark of autoinflammatory bone disorders, including chronic nonbacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO). Autoinflammatory osteopathies are the result of a dysregulated innate immune system, resulting in immune cell infiltration of the bone and subsequent osteoclast differentiation and activation. Interestingly,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881012
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Oct 24, 2014
10/14
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Hill, Andrew F.; Pegtel, D. Michiel; Lambertz, Ulrike; Leonardi, Tommaso; O'Driscoll, Lorraine; Pluchino, Stefano; Ter-Ovanesyan, Dmitry; Nolte-'t Hoen, Esther N.M.
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eye 48
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This article is from Journal of Extracellular Vesicles , volume 2 . Abstract Extracellular vesicles (EVs) are the collective term for the various vesicles that are released by cells into the extracellular space. Such vesicles include exosomes and microvesicles, which vary by their size and/or protein and genetic cargo. With the discovery that EVs contain genetic material in the form of RNA (evRNA) has come the increased interest in these vesicles for their potential use as sources of disease...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873759
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Oct 27, 2014
10/14
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Hoarau, Jean-Jacques; Gay, Frederick; Pelle, Olivier; Samri, Assia; Jaffar-Bandjee, Marie-Christine; Gasque, Philippe; Autran, Brigitte
texts
eye 54
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This article is from PLoS ONE , volume 8 . Abstract To characterize the immunity developed by patients infected by chikungunya virus (CHIKV), we studied the intensity and specificity of CHIKV-specific T cells mediated responses in chronic and recovered patients at 12 to 24 months post-infection. T cells were challenged in vitro against CHIKV synthetic peptides covering the length of three viral proteins, capsid, E2 and nsP1 proteins as well as all inactivated virus particles. Cytokine...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871564
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Oct 24, 2014
10/14
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Hong, Seok Ha; Im, Sun; Park, Geun-Young
texts
eye 62
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This article is from Annals of Rehabilitation Medicine , volume 37 . Abstract Objective: To explore the effect of visual and haptic vertical stimulation on standing balance in post-stroke patients. Methods: Twenty-five post-stroke patients were recruited. We measured left/right standing pressure differences and the center of pressure (COP) parameters for each patient under three different conditions: no stimulation, visual, and haptic stimulated conditions. First, patients stood on a...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895526
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Oct 23, 2014
10/14
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Hooshfar, Shirin; Mortazavi, Seyed Alireza; Piryaei, Mohammad; Ramandi Darzi, Hossein; Shahsavari, Nahid; Kobarfard, Farzad
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eye 76
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This article is from Iranian Journal of Pharmaceutical Research : IJPR , volume 13 . Abstract A gradient reversed-phase high performance liquid chromatography (HPLC) method was developed for the assay of cetrorelix acetate, a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity used in infertility treatment. The HPLC method, which is used to determine cetrorelix in bulk and pharmaceutical dosage forms, was validated per ICH guidelines. The chromatographic...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977052
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Oct 23, 2014
10/14
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Howard, Thomas P.; Fahy, Brendan; Leigh, Fiona; Howell, Phil; Powell, Wayne; Greenland, Andy; Trafford, Kay; Smith, Alison M.
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eye 13
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This article is from Journal of Cereal Science , volume 59 . Abstract The effects on barley starch and grain properties of four starch synthesis mutations were studied during the introgression of the mutations from diverse backgrounds into an elite variety. The lys5f (ADPglucose transporter), wax (granule-bound starch synthase), isa1 (debranching enzyme isoamylase 1) and sex6 (starch synthase IIa) mutations were introgressed into NFC Tipple to give mutant and wild-type BC2F4 families with...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990431
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51
Oct 24, 2014
10/14
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Huw, L-Y; O'Brien, C; Pandita, A; Mohan, S; Spoerke, J M; Lu, S; Wang, Y; Hampton, G M; Wilson, T R; Lackner, M R
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eye 51
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This article is from Oncogenesis , volume 2 . Abstract Agents targeting the PI3K/mTOR signaling axis have shown promise in early-phase clinical trials and are currently being studied in later stages of clinical development in multiple indications. Experience with other targeted agents suggests that clinical responses may be short-lived because of acquired resistance to therapy. Here, we report preclinical modeling of acquired resistance in a HER2-positive, PIK3CA mutant breast cancer cell line,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940863
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Oct 28, 2014
10/14
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Jang, Seung-Gul; Pyun, Sung-Bom
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eye 46
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This article is from Annals of Rehabilitation Medicine , volume 37 . Abstract Kernohan-Woltman notch phenomenon (KWP) is an ipsilateral motor weakness due to compression of the contralateral cerebral peduncle. We report two cases of KWP following traumatic brain injury. In case 1, ipsilateral hemiplegia was noted after right subdural hemorrhage. Although magnetic resonance imaging showed no abnormal signal changes on cerebral peduncle, diffusion tensor tractography (DTT) revealed interruption...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895529
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Oct 23, 2014
10/14
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Khasnis, Sandhya Anand; Kidiyoor, Krishnamurthy Haridas; Patil, Anand Basavaraj; Kenganal, Smita Basavaraj
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eye 19
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This article is from Journal of Conservative Dentistry : JCD , volume 17 . Abstract Vertical root fractures associated with endodontically treated teeth and less commonly in vital teeth represent one of the most difficult clinical problems to diagnose and treat. In as much as there are no specific symptoms, diagnosis can be difficult. Clinical detection of this condition by endodontists is becoming more frequent, where as it is rather underestimated by the general practitioners. Since, vertical...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001262
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Oct 25, 2014
10/14
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Kim, Mi-Young; Chung, Cho-Yun; Kim, Jong-Sun; Myung, Dae-Seong; Cho, Sung-Bum; Park, Chang-Hwan; Kim, Young; Joo, Young-Eun
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eye 76
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This article is from Chonnam Medical Journal , volume 49 . Abstract We report the first case of hypercalcemia-induced acute pancreatitis caused by a functioning parathyroid cyst in a 67-year-old man. Laboratory investigation revealed increased serum amylase and lipase, increased serum ionized calcium and parathyroid hormone (PTH) levels, and decreased serum phosphate, indicating pancreatitis and primary hyperparathyroidism (PHPT). Abdominal computed tomography (CT) revealed mild swelling of the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881208
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Oct 28, 2014
10/14
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Kim, Se Yon; Park, Moon-Sung; Yang, Jeong-In; Yim, Shin-Young
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eye 57
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This article is from Annals of Rehabilitation Medicine , volume 37 . Abstract Objective: To compare effectiveness on correcting cranial and ear asymmetry between helmet therapy and counter positioning for deformational plagiocephaly (DP). Methods: Retrospective data of children diagnosed with DP who visited our clinic from November 2010 to October 2012 were reviewed. Subjects ≤10 months of age who showed ≥10 mm of diagonal difference were included for analysis. For DP treatment, information...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895518
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Oct 24, 2014
10/14
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Kim, Soo Yeon; Park, Hye Kyung; Song, Dae Heon; Chung, Myung Eun; Kim, Young Moon; Woo, Jae Hyun
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eye 63
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This article is from Annals of Rehabilitation Medicine , volume 37 . Abstract Ptosis could be caused by oculomotor nerve palsy in the midbrain infarction. Bilateral ptosis has been reported in several reports, which focused on clinical characteristics of midbrain infarction. Little research attention has been paid to the treatment of patients with bilateral ptosis in midbrain infarction. We experienced a case of severe bilateral ptosis occurring after midbrain infarction. The patient could not...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895531
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Oct 24, 2014
10/14
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Kotecha, Rishi S.; Buckland, Amy; Phillips, Marianne B.; Cole, Catherine H.; Gottardo, Nicholas G.
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eye 54
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This article is from Journal of Pediatric Hematology/Oncology , volume 36 . Abstract Hepatic sinusoidal obstruction syndrome (HSOS), also known as veno-occlusive disease, is a well-recognized toxic complication after autologous and allogeneic hematopoietic stem cell transplant, during treatment of Wilms tumor and rhabdomyosarcoma associated with actinomycin-D, and during acute lymphoblastic leukemia therapy due to oral 6-thioguanine. However, its occurrence in the context of chemotherapy...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872829
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Oct 28, 2014
10/14
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Laurent, Carine; Leduc, Alexandre; Pottier, Ivannah; Prevost, Virginie; Sichel, Francois; Lefaix, Jean-Louis
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eye 44
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This article is from PLoS ONE , volume 8 . Abstract Skin complications were recently reported after carbon-ion (C-ion) radiation therapy. Oxidative stress is considered an important pathway in the appearance of late skin reactions. We evaluated oxidative stress in normal human skin fibroblasts after carbon-ion vs. X-ray irradiation. Survival curves and radiobiological parameters were calculated. DNA damage was quantified, as were lipid peroxidation (LPO), protein carbonylation and antioxidant...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871598
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Oct 25, 2014
10/14
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Lin, Li; Hutzen, Brian; Lee, Hsiu-Fang; Peng, Zhengang; Wang, Wenlong; Zhao, Chongqiang; Lin, Huey-Jen; Sun, Duxin; Li, Pui-Kai; Li, Chenglong; Korkaya, Hasan; Wicha, Max S.; Lin, Jiayuh
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eye 49
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This article is from PLoS ONE , volume 8 . Abstract Background: STAT3 activation is frequently detected in breast cancer and this pathway has emerged as an attractive molecular target for cancer treatment. Recent experimental evidence suggests ALDH-positive (ALDH+), or cell surface molecule CD44-positive (CD44+) but CD24-negative (CD24−) breast cancer cells have cancer stem cell properties. However, the role of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24− subpopulations of breast cancer...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871589
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Oct 28, 2014
10/14
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Maacha, Selma; Planque, Nathalie; Laurent, Cecile; Pegoraro, Caterina; Anezo, Oceane; Maczkowiak, Frederique; Monsoro-Burq, Anne H.; Saule, Simon
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eye 59
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This article is from PLoS ONE , volume 8 . Abstract Uveal melanoma is the most common intraocular malignancy in adults, representing between about 4% and 5% of all melanomas. High expression levels of Protein Tyrosine Phosphatase 4A3, a dual phosphatase, is highly predictive of metastasis development and PTP4A3 overexpression in uveal melanoma cells increases their in vitro migration and in vivo invasiveness. Melanocytes, including uveal melanocytes, are derived from the neural crest during...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871671
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Oct 28, 2014
10/14
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Mamedov, Ilgar Z.; Britanova, Olga V.; Zvyagin, Ivan V.; Turchaninova, Maria A.; Bolotin, Dmitriy A.; Putintseva, Ekaterina V.; Lebedev, Yuriy B.; Chudakov, Dmitriy M.
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eye 110
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This article is from Frontiers in Immunology , volume 4 . Abstract High-throughput sequencing has the power to reveal the nature of adaptive immunity as represented by the full complexity of T-cell receptor (TCR) and antibody (IG) repertoires, but is at present severely compromised by the quantitative bias, bottlenecks, and accumulated errors that inevitably occur in the course of library preparation and sequencing. Here we report an optimized protocol for the unbiased preparation of TCR and IG...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870325
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Oct 24, 2014
10/14
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Meir, Jessica U.; Robinson, Patrick W.; Vilchis, L. Ignacio; Kooyman, Gerald L.; Costa, Daniel P.; Ponganis, Paul J.
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eye 53
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This article is from PLoS ONE , volume 8 . Abstract Although energetics is fundamental to animal ecology, traditional methods of determining metabolic rate are neither direct nor instantaneous. Recently, continuous blood oxygen (O2) measurements were used to assess energy expenditure in diving elephant seals (Mirounga angustirostris), demonstrating that an exceptional hypoxemic tolerance and exquisite management of blood O2 stores underlie the extraordinary diving capability of this consummate...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871621
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Oct 28, 2014
10/14
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Mettler, Tobias; Stump, Reto; Haueis, Silvia; Kalt, Nicola; Tschuor, Christoph; Limani, Perparim; Raptis, Dimitri A; Puhan, Milo A; Breitenstein, Stefan
texts
eye 12
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This article is from JMIR Research Protocols , volume 2 . Abstract Background: Hepatic metastases of neuroendocrine tumors (NETs) are considered a major prognostic factor associated with significantly reduced survival compared to patients without liver metastases. Several surgical and nonsurgical strategies are present to treat resectable and nonresectable liver metastases, some of which have the potential to cure liver mestatases. Objective: The aims of the four systematic reviews presented in...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875902
43
43
Oct 24, 2014
10/14
by
Nagaraja, Tavarekere N.; Aryal, Madhava P.; Brown, Stephen L.; Bagher-Ebadian, Hassan; Mikkelsen, Tom; Yang, James J.; Panda, Swayamprava; Keenan, Kelly A.; Cabral, Glauber; Ewing, James R.
texts
eye 43
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This article is from PLoS ONE , volume 8 . Abstract Increased efficacy of radiotherapy (RT) 4-8 h after Cilengitide treatment has been reported. We hypothesized that the effects of Cilengitide on tumor transvascular transfer parameters might underlie, and thus predict, this potentiation. Athymic rats with orthotopic U251 glioma were studied at ~21 days after implantation using dynamic contrast-enhanced (DCE)-MRI. Vascular parameters, viz: plasma volume fraction (vp), forward volume transfer...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871527
15
15
Oct 23, 2014
10/14
by
Oberdorfer, Bernd; Setman, Daria; Steyskal, Eva-Maria; Hohenwarter, Anton; Sprengel, Wolfgang; Zehetbauer, Michael; Pippan, Reinhard; Wurschum, Roland
texts
eye 15
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This article is from Acta Materialia , volume 68 . Abstract The release of excess volume upon recrystallization of ultrafine-grained Cu deformed by high-pressure torsion (HPT) was studied by means of the direct technique of high-precision difference dilatometry in combination with differential scanning calorimetry (DSC) and scanning electron microscopy. From the length change associated with the removal of grain boundaries in the wake of crystallite growth, a structural key quantity of grain...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990421
78
78
Oct 23, 2014
10/14
by
Oliver, Bonamy R.; Trzaskowski, Maciej; Plomin, Robert
texts
eye 78
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This article is from Developmental Psychology , volume 50 . Abstract Reviews of behavioral genetic studies note that “control” aspects of parenting yield low estimates of heritability, while “affective” aspects (parental feelings) yield moderate estimates. Research to date has not specifically considered whether positive and negative aspects of parenting—for both feelings and control—may explain these etiological distinctions. We addressed this issue using parent reports of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977675
71
71
Oct 23, 2014
10/14
by
Park, Sang-Jin; Lim, Kwang-Hyun; Noh, Jeong-Ho; Jeong, Eun Ju; Kim, Yong-Soon; Han, Byung-Cheol; Lee, Seung-Ho; Moon, Kyoung-Sik
texts
eye 71
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This article is from Toxicological Research , volume 29 . Abstract Ginseng is a well-known traditional medicine used in Asian countries for several thousand years, and it is currently applied to medicine, cosmetics, and nutritional supplements due to its many healing and energygiving properties. It is well demonstrated that ginsenosides, the main ingredient of ginseng, produce a variety of pharmacological and therapeutic effects on central nerve system (CNS) disorders, cardiovascular disease,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936181
118
118
Oct 23, 2014
10/14
by
Parvinroo, Shirin; Zahediasl, Saleh; Sabetkasaei, Masoumeh; Kamalinejad, Mohammad; Naghibi, Farzaneh
texts
eye 118
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This article is from Iranian Journal of Pharmaceutical Research : IJPR , volume 13 . Abstract This study was aimed to evaluate the effects of diets containing some hot and cold temperament herb seeds according to Iranian traditional medicine (ITM) on some metabolic parameters in acute (24 h) and sub-acute (7 day) experiments that were performed on rats. For each experiment, effects of diets containing 10% herb seeds in category of hot (anise, fennel, ajowan) and cold (cucumber, watermelon,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977068
9
9.0
Jun 8, 2021
06/21
by
Pascal (swing)
data
eye 9
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Customized version of http://www.thingiverse.com/thing:58001 Created with Customizer! http://www.thingiverse.com/apps/customizer/run?thing_id=58001
Topics: Accessories, customized, stl, thingiverse
9
9.0
Jun 8, 2021
06/21
by
Pascal (swing)
data
eye 9
favorite 0
comment 0
Customized version of http://www.thingiverse.com/thing:58001 Created with Customizer! http://www.thingiverse.com/apps/customizer/run?thing_id=58001
Topics: Accessories, customized, stl, thingiverse
9
9.0
Mar 19, 2021
03/21
by
Patrick (pharmboyz)
data
eye 9
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Brand name ibuprofen has a syringe adapter for a proprietary syringe, but 5ml (or smaller/larger) are cheaper, more available and can be used again and again for other bottles. These adapters create a seal with the appropriate hole for the syringe to draw the liquid up without mess or fuss. Simply measure the inner diameter of your bottle with a caliper and rework the file for your own use.
Topics: thingiverse, 3D Printing, stl
9
9.0
Apr 7, 2021
04/21
by
Paulo Amaral (PauloAmaral)
data
eye 9
favorite 0
comment 0
Scanned with the Sense 3D Scanner
Topics: stl, thingiverse, Sculptures
9
9.0
Mar 19, 2021
03/21
by
Paulo Amaral (PauloAmaral)
data
eye 9
favorite 0
comment 0
Scanned with the Sense 3D Scanner
Topics: thingiverse, Sculptures, stl
