8
8.0
Apr 28, 2021
04/21
by
Wang, Lihua
texts
eye 8
favorite 1
comment 0
372 p. ; 24 cm
Topic: Yi dong zhong duan -- Ying yong cheng xu -- Cheng xu she ji
16
16
Feb 18, 2022
02/22
by
Wang, Lihua
texts
eye 16
favorite 2
comment 0
293 pages : 24 cm
Topics: Medicine, Chinese, Medicine, Popular, Medicina china, Medicina del hogar
11
11
Sep 15, 2019
09/19
by
Wang, Lihua
texts
eye 11
favorite 0
comment 0
2 volumes ; 23 cm
Topics: Chinese literature -- History and criticism, Gu dian wen xue -- wen xue shi -- dui wai han yu jiao...
63
63
Oct 6, 2014
10/14
by
Wei, Wen; Fan, Zhaoshan; Wang, Lihua; Li, Zhiwei; Jiao, Wanzhen; Li, Yun
texts
eye 63
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Purpose: To determine the distributions and relation of central corneal thickness (CCT) and intraocular pressure (IOP) by NT-530P in Chinese juveniles, and the effect of gender, age, height, weight and refractive errors on the CTT and IOP. Methods: CCT and IOP of 982 eyes in 514 juveniles aged from 7 to 18 years were measured with NT-530P. Multi-linear regression and ANOVA analysis were used to analyze the relation of CCT and IOP, and the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141688
63
63
Oct 16, 2014
10/14
by
Lingappan, Krithika; Srinivasan, Chandra; Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi I.; Moorthy, Bhagavatula
texts
eye 63
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Exposure to high concentration of oxygen (hyperoxia) leads to lung injury in experimental animal models and plays a role in the pathogenesis of diseases such as Acute Respiratory Distress Syndrome (ARDS) and Bronchopulmonary dysplasia (BPD) in humans. The mechanisms responsible for sex differences in the susceptibility towards hyperoxic lung injury remain largely unknown. The major goal of this study was to characterize the changes in the...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086819
55
55
Oct 28, 2014
10/14
by
Lior-Hoffmann, Lee; Wang, Lihua; Wang, Shenglong; Geacintov, Nicholas E.; Broyde, Suse; Zhang, Yingkai
texts
eye 55
favorite 0
comment 0
This article is from Nucleic Acids Research , volume 40 . Abstract Human DNA Pol κ is a polymerase enzyme, specialized for near error-free bypass of certain bulky chemical lesions to DNA that are derived from environmental carcinogens present in tobacco smoke, automobile exhaust and cooked food. By employing ab initio QM/MM–MD (Quantum Mechanics/Molecular Mechanics–Molecular Dynamics) simulations with umbrella sampling, we have determined the entire free energy profile of the nucleotidyl...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467051
77
77
Oct 8, 2014
10/14
by
Wang, Lihua; Teng, Jiao; Liu, Pan; Hirata, Akihiko; Ma, En; Zhang, Ze; Chen, Mingwei; Han, Xiaodong
texts
eye 77
favorite 0
comment 0
This article is from Nature Communications , volume 5 . Abstract Grain rotation is a well-known phenomenon during high (homologous) temperature deformation and recrystallization of polycrystalline materials. In recent years, grain rotation has also been proposed as a plasticity mechanism at low temperatures (for example, room temperature for metals), especially for nanocrystalline grains with diameter d less than ~15 nm. Here, in tensile-loaded Pt thin films under a high-resolution...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109021
68
68
Oct 27, 2014
10/14
by
Mu, Hong; Kropachev, Konstantin; Wang, Lihua; Zhang, Lu; Kolbanovskiy, Alexander; Kolbanovskiy, Marina; E. Geacintov, Nicholas; Broyde, Suse
texts
eye 68
favorite 0
comment 0
This article is from Nucleic Acids Research , volume 40 . Abstract Nucleotide excision repair (NER) efficiencies of DNA lesions can vary by orders of magnitude, for reasons that remain unclear. An example is the pair of N-(2′-deoxyguanosin-8-yl)-2-aminofluorene (dG-C8-AF) and N-(2′-deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-C8-AAF) adducts that differ by a single acetyl group. The NER efficiencies in human HeLa cell extracts of these lesions are significantly different when placed at G1,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479214
47
47
Oct 23, 2014
10/14
by
He, Xiaoping; Cao, Yang; Wang, Lihua; Han, Yingli; Zhong, Xiuying; Zhou, Guixiang; Cai, Yongping; Zhang, Huafeng; Gao, Ping
texts
eye 47
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Induction of pluripotent stem cells (iPSC) by defined transcription factors is the recognized canonical means for somatic reprogramming, however, it remains incompletely understood how individual transcription factors affect cell fate decisions during the reprogramming process. Here, we report induction of fibroblast reprogramming by various transcriptional factors is mediated by a miR19a/b-PTEN axis. cMyc, one of the four Yamanaka factors...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989277
53
53
Oct 28, 2014
10/14
by
Xu, Hui; Gao, Shuli; Liu, Quanwen; Pan, Dun; Wang, Lihua; Ren, Shuzhen; Ding, Min; Chen, Jingwen; Liu, Gang
texts
eye 53
favorite 0
comment 0
This article is from Sensors (Basel, Switzerland) , volume 11 . Abstract We here report a rapid, sensitive, selective and label-free fluorescence detection method for cysteine (Cys). The conformation of mercury-specific DNA (MSD) changes from a random coil form to a hairpin structure in the presence of Hg2+ due to the formation of a thymine-Hg2+-thymine (T-Hg2+-T) complex. Cys can selectively coordinate with Hg2+ and extract it from the thymine-Hg2+-thymine complex. The hairpin structure...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274280
65
65
Oct 11, 2014
10/14
by
Ning, Shangwei; Zhao, Zuxianglan; Ye, Jingrun; Wang, Peng; Zhi, Hui; Li, Ronghong; Wang, Tingting; Wang, Jianjian; Wang, Lihua; Li, Xia
texts
eye 65
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract Large intergenic non-coding RNAs (lincRNAs) are a new class of functional transcripts, and aberrant expression of lincRNAs was associated with several human diseases. The genetic variants in lincRNA transcription factor binding sites (TFBSs) can change lincRNA expression, thereby affecting the susceptibility to human diseases. To identify and annotate these functional candidates, we have developed a database SNP@lincTFBS, which is devoted to...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116217
71
71
Oct 23, 2014
10/14
by
Ren, Zijia; Kang, Wenyao; Wang, Lihua; Sun, Baoliang; Ma, Jiajia; Zheng, Chaogu; Sun, Jie; Tian, Zhigang; Yang, Xiaoyi; Xiao, Weihua
texts
eye 71
favorite 0
comment 0
This article is from Molecular Cancer , volume 13 . Abstract Background: E2F1 is the gatekeeper of the cell cycle controlling an analogous balance between proliferation and cell death. E2F1 expression is elevated in advanced prostate cancer. However, it is still unclear that the roles and mechanisms of E2F1 on prostate cancers. Methods: Targeted knockdown by interferon RNA was applied on two prostate cancer and Hela cell lines to examine the inverse correlation expression of E2F1 and ICAM-1....
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004456
43
43
Oct 22, 2014
10/14
by
Gao, Jun; Wang, Lihua; Xu, Jinkang; Zheng, Jianming; Man, Xiaohua; Wu, Hongyu; Jin, Jin; Wang, Kaixuan; Xiao, Huasheng; Li, Shude; Li, Zhaoshen
texts
eye 43
favorite 0
comment 0
This article is from Journal of Experimental & Clinical Cancer Research : CR , volume 32 . Abstract Background: Altered gene methylation, regulated by DNA methyltransferases (DNMT) 1, 3a and 3b, contributes to tumorigenesis. However, the role of DNMT in pancreatic ductal adenocarcinoma (PDAC) remains unknown. Methods: Expression of DNMT 1, 3a and 3b was detected in 88 Pancreatic ductal adenocarcinoma (PDAC) and 10 normal tissue samples by immunohistochemistry. Changes in cell viability,...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029463
48
48
Oct 28, 2014
10/14
by
Wang, Lihua; Liu, Pan; Guan, Pengfei; Yang, Mingjie; Sun, Jialin; Cheng, Yongqiang; Hirata, Akihiko; Zhang, Ze; Ma, Evan; Chen, Mingwei; Han, Xiaodong
texts
eye 48
favorite 0
comment 0
This article is from Nature Communications , volume 4 . Abstract The elastic strain sustainable in crystal lattices is usually limited by the onset of inelastic yielding mediated by discrete dislocation activity, displacive deformation twinning and stress-induced phase transformations, or fracture associated with flaws. Here we report a continuous and gradual lattice deformation in bending nickel nanowires to a reversible shear strain as high as 34.6%, which is approximately four times that of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778763
50
50
Oct 8, 2014
10/14
by
Yang, Lili; Wang, Jianjian; Sun, Xuesong; Cao, Yuze; Ning, Shangwei; Zhang, Huixue; Chen, Lixia; Li, Ronghong; Tian, Qinghua; Wang, Lihua; Wang, Weizhi; Li, Xia
texts
eye 50
favorite 0
comment 0
This article is from PLoS ONE , volume 9 . Abstract The significant roles of genetic variants in myasthenia gravis (MG) pathogenesis have been demonstrated in many studies, and recently it has been revealed that aberrant level/regulation of microRNAs (miRNAs) might contribute to the initiation and progression of MG. However, the dysfunction of miRNA associated with single nucleotide polymorphisms (miRSNPs) has not been well investigated in MG. In this study, we created a contemporary catalog of...
Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130595
