at the great poignancy of this is at some point alzheimer's kicks in and there's been an interesting debate, probably -- first acknowledged he had alzheimer's several years after leaving the white house when he wrote this moving letter to the country in 1994 about when alzheimer's started to have an effect. this actually had delicious fight going on between bill o'reilly and george will about it and george will says bill o'reilly in the killing reagan book has liabled reagan by saying that alzheimer's was affecting him earlier in this presidency. in fact, i looked at the o'reilly books he doesn't say what will says -- accuse otherwise him saying which is the assassination attempt and the recovery kick started his alzheimer's. he said it had a big physical effect on him, which everyone around reagan said it did. reagan was slower, his hearing woes, his recognize of people was worse after he was shot. i think the best evidence suggests that alzheimer's really started to affect himmin' 1986, around the time of iran-contra, around the time when he was most embarrassingly unable to rememb

moving letter to the country in 1994 about when alzheimer's started to have an effect. is actually had delicious fight going on between bill o'reilly and george will about it. george will says we'll o'reilly says he has libeled reagan i think alzheimer's was affecting him earlier in his presidency. in fact, i look at the o'reilly book. he doesn't say what george will accuses him of saying which was about the assassination attempt and recover from that sort of kick started his alzheimer's. he said it had a big physical effect on in which everyone around ronald reagan did, to reagan was slower, his hearing was worse, his recognition of people was worse after he was shot. i think the best evidence suggests that alzheimer's will start to affect him in 1986 around the time of iran-contra, around the time he was most embarrassingly unable to remember what had happened. people assumed it was convenient not remembering. i think by that point it's actual not remembering. i think when the question of what did he know and when did he know it became a sort of conundrum because he d

then you get further along in its how you can start to recognize the alzheimer's. they either got movies or had to be sent that he does write very enthusiastically. he seems to be more responsive to the movies and the people are not present. he's paying attention and gets offended when there's bad language. i think there was one kind of reading and at another if he was engaged in political literature he liked to read the newspaper added and the aides would keep it away from him because he would say things that were not true and he would be finding it and getting it back. if you want to get a sense of how he's always transcripts of the commentary from the late 70s it's the most interesting thing and they are written out in longhand with very few scratch out. we give them a call on and if we are looking for a political columnist they are somewhat different and pretty far off but they were original and interesting and had that quality you may disagree with but it's compelling and you want to keep listening or reading. i just did a write up of exactly this if you want

cell loss of smell is the first clinical symptoms of alzheimer's. this is not budget tactical talks but one of the school applications and just to talk about how all emerson these technologies can be. so my first experience was 2,008 at stanford university. the first experience if you were ever in a pit simulation before. you have to walk over. united is the immediate experience how you feel and course it is a test. and ed i did immediately. what do with your arms? don't need for balance. he said people have of the worst experiences they screen a had run across the board another just couldn't do the story but i said what happens if i'd jump off? he said try it. i fell the end it was amazing but it was like going off the cliff and the roadrunner kirk -- gertrude lead now falls standing up sulindac to research and wanted to see a virtual reality had changed. to make the experience more holistic what i saw was amazingly real. and had this amazing experience rice spent time with a national guard units. to participate in a clinical trial with the idea to

i also was attracted to her this summer when she started talking about alzheimer's research. an offense that she thought would be important to put into that research. my family has been greatly touched by alzheimer's, so i'm really interested in the work she is living. >> have been supporting hillary because he has the most experience, the most qualified and both sides of the aisle. she takes it very seriously. she supports women and children her entire life. as a mother of three daughters, it is high time we elect a female president. [applause]. >> we have rick miller who is speaking as a surrogate for martin o'malley [applause]. >> as a democrat i feel blessed that we have three fantastic candidates. i am not going to beat around the bush. it has been a very hard choice for me. i made it not very early. i really looked at all three candidates and realized that one candidate is great in foreign affairs, another one has energy to spare, and then we have o'malley who has all the experience as far as being an executive in the governor's position in maryland and as mayor of balt

i also was attracted to her this summer when she started talking about alzheimer's research. an offense that she thought would be important to put into that research. my family has been greatly touched by alzheimer's, so i'm really interested in the work she is living. >> have been supporting hillary because he has the most experience, the most qualified and both sides of the aisle. she takes it very seriously. she supports women and children her entire life. as a mother of three daughters, it is high time we elect a female president. [applause]. >> we have rick miller who is speaking as a surrogate for martin o'malley [applause]. >> as a democrat i feel blessed that we have three fantastic candidates. i am not going to beat around the bush. it has been a very hard choice for me. i made it not very early. i really looked at all three candidates and realized that one candidate is great in foreign affairs, another one has energy to spare, and then we have o'malley who has all the experience as far as being an executive in the governor's position in maryland and as mayor of balt

so, the good news is that a was a lot of things if you have als or alzheimer's or pancreatic cancer there isn't that much that can be done to wait for the next. we can make a huge difference we just don't provide it in an accessible way. so i think this is really the only way that gets the attention for some individual that is mentally ill and is not treated. these are like the tips of the iceberg that occur whether it is homelessness or the number of mentally ill people in prison or the rise of the rape to domestic violence or mass violence that is occurring. the rate of suicide in the country hasn't gone down in over a century. it's decreased by 50% in the last half-century so we don't take it seriously. it's not a random events. it occurs 90% of people. many of the people, the majority have seen health professionals in the month prior to committing suicide. there is was a story in the news recently about this navy seal committing suicide after ptsd after being in the tours of duty and loss of colleagues at high risk so it was a lot of social and political will more than the lack of kno

. >> the good news is that with a lot ofthings , if you have als or alzheimer's, if you have pancreatic cancer, there's not much then can be done. you need to wait for the rest to be discovered but for the mass majority of mental disorders , as i can find them, we only have enough to make a huge difference. we just don't provide it in an accessible way so the only way that this gets the attention of the media, the public and government is when there's a mass violent incident and some individual who is mentally ill and untreated kills people. >> watch for these programs and more this weekend on book tv. >> alan friedman has been a correspondent for numerous organizations over the past 30 years including the wall street journal, the financialtimes. he's the author of a new book, the epic story of the billionaire who took over italy. you get access to silvio berlusconi . >> i managed to persuade former prime minister bliss tony back in the early 2014to give me his time and we ended up spending 18 months together. i said i was going to do this on the model of frost nixon . we were going to

they were cancer, heart disease, diabetes and alzheimer's. those for collectively have massive, massive costs. i believe we need to dramatically increase the research that goes into cures than trying to cure one, two, three, or even four of those big diseases. and doing so, if we could your even one we would literally save millions of lives and hundreds of billions or even trillions of medicare. alzheimer's alone is projected to cost over a trillion dollars in care. my grandmother died of alzheimer's. it is a horrible, horrible disease. and yet we are spending pennies on research and a trillion dollars on the back and on care for it doesn't make any sense be well to invest in the front end because if we didn't care if we save a trillion dollars. not to mention lives. [applause] there is another component of that. which is, one of the barriers to curing diseases is the regulatory processes in washington. that are incredibly slow and cumbersome. to get a new drug or medical device through the fda can take years, upwards of a billion dollars to

the good news is, you know, with a lot of things if you have als, alzheimer's, if you have panceatic cancer, it's not much that can be done. we need to wait for the next discovery but for the vast majority of mental disorders as i've defined them, we already have enough to make a huge difference. we just don't provide it in accurate accessible way, i think this is the only way that this kind of gets the attention, the media, public government is when there's mass violence incidents and some individual who is mentally ill and the untreated kills people. these are like the tips to have iceberg, glaring social pathtologies that occur as a result of a failed mental health policy. whether it's homelessness, mental-ill people in prison, rising rates of domestic violence or mass violence that's occurring, suicide, the rate of suicide in this country has not gone down in over centuries. we don't take them seriously. suicide is not a random event. many of the people, the majority have seen -- a health professional in the month prior to committing suicide. the story in the news recently about

. >> the good news is is that with a lot of things if you have als from alzheimer's, pancreatic cancer, there is not much that can be done. the vast majority we only have enough to make a huge difference. we just don't provided in an accessible way. the only way that this kind of gets the attention of mass violence incident. untreated and kills people. >> watch for these programs and more.

i said one example is alzheimer's. i was surprised when my staff said one american is diagnosed with alzheimer's every 67 seconds. i said go back to the drawing board. that can't be true. they went back and came and said no, senator, that's exactly right. once every 67 seconds on average an american is diagnosed with alzheimer's. i told that story to ernest moniz, the secretary of energy. i said that's why we need this n.i.h. research. he said senator, my office of science in the department of energy is developing the imaging techniques so is that we can detect alzheimer's in living human beings. currently the only confirmation of diagnosis is coming through autopsy. if we can find early onset of alzheimer's we are in a better position to respond to it. that's why if you're interested in curing diseases, in finding ways to avoid expensive surgery, reducing the cost of medicine but still protecting america, we need, as this generation of lawmakers, to make a commitment to science research. i've already thanked my collea

in putting this out there because my father has been very involved in the subject of alzheimer's, but he was a venture capitalist. he is actually started companies, nonprofits to attract investors, and what they are doing is certain doctors and programs that have a potentially excellent success rate. >> tended to cancer program. they put $50 million in the hands of doctors like this is thought to go through these hoops. >> thank you for coming. how close are we talking in the laboratory conjuring blank coming up with a diagnosis make. >> well, there are companies now that exist solely for that purpose. .. i heard it's unique to mammals and therefore we have some kind of receptors. how are we doing in that department or is that just kind of propaganda? >> no. we have receptors in our brain for morphine. morphine attached and the reason you get high on morphine -- there's no surprise for ones that come from plants are the same kind of receptors. marijuana works. it was a fine time to walk down the hall. [laughter] >> making people eat and having

. >> if you have als, alzheimer's, pancrease cancer, there is not much that can be done. you need to wait for the next discovery. but for the vast majority of mental disorders as i define them we have enough to make a huge difference. we just don't provide it in an accessible way. so i think -- and you know the only way that this kind of gets the attention of the media, public and government is when there is a mass violence into this and some individual who is mentally ill and untreated kills people. >> watch for these programs and more this weekend on booktv. >> host: peter bergen in your new book you write americans have long tended to overestimates the threats posed by jihadist >> guest: 80% of americans are somewhat or very worried about terrorism as an issue and 24% of republicans think it is the leading political issue in the election season, 9% of democrats. and you know some of that is understandable with the attack on metro jet and the attack in paris with 130 killed people and in san bernardino, california 14 people killed by people inspired by isis. the threat

medicine and we need to tackle some of the greatest medical challenges of our time like cancer, and alzheimer's. we have to ask ourselves how we are going to guarantee that we have the research, the market, and the access to make sure the benefits from that lifesaving progress i felt across the system as a whole. we also have to make sure that insurers are covering their fair share. we made important progress capping out of pocket spending as part of the affordable care act. there's more act work to do to make sure that patients are not being saddled with too heavy a cost burden. i'm concerned that we must prevent carriers from discriminating against patients with the most expensive illnesses. in addition, if our if our goal is to make sure patients have access to and can afford the best most effective cures and treatments, we have to consider the resources we are putting into this effort. the truth is, we cannot cannot realize the goal of access, quality and affordability without the fda and full throttle. if you want the fda to be able to approve drugs more quickly, without rolling back the g

with alzheimer's with that data. when and then they have the proteins piling up. had with a number of us of compounds with those antibodies wanda's austria in europe and said diego. and even those simple molecules. is the corridors of the puzzle. and billy could the start that but there are cells that die. end it just isn't worth it. because a lot of this is naked find a way to get in there. some really is a part of congress really. so i think there is some hope. >> her believe they deal with a garbage. if there were hundreds they look like a garbage disposals there around the whole of the middle. and then invest his them not. has anybody ever put in artichoke down the garbage disposal? >> it doesn't mark and that is what happens. they choke. if we could find a way to break it down or find a way to reduce a and to get rid of it i think we're starting to get there. there is a lot going on with these into body studies it is an exciting time. >> and never would have said that before. >> and a meeting cleared before congress the first time he announced he had parkinso

i'm putting this out there because our father has been very involved with alzheimer's but he was a venture capitalist. he is actually now started a company it is a nonprofit, but they are using the venture capitalists method to attract investors and what they're doing is finding certain doctors in certain programs that they think have a potentially excellent success rate and putting money behind it. >> yes i think that is very good. the stand up to cancer program does that. again, when they put $50 million in the hands of doctors like that they still have to go through all of these hoops. the $50 million goes in and there's a pinhole at the other and to squeeze stuff out. there are few people up front who have been raising their hands. >> how close are we to walking into a laboratory, contributing five cc of blood and coming up with a diagnosis of cancer via dna sequencing. >> i don't know. there are companies now that exists solely for that purpose. it's a real difficult test to prove. it takes a long time to prove that it will actually show if you're diagnosing cancer. there are a lot of

is immoral and by the way we interest -- the interest just think defeated 100 billion on research on alzheimer's the we cannot seem to control this. the was the russian than we did. one of the most boring questions for those who know me it is a joke. ragged was never in the establishment lained. i remember in 1976. they said he was an actor and done in did not know what he was doing. he kicked the door down and said kitcat of flyaway. to remove america. this is happening because we don't have a theater to get people raised to hire an still liquid doesn't affect. >> who else. >> but there are three things that we need to grow jobs. common-sense regulation there the engine of job creation. we go there big game and we know their brand but those who change america are the entreprenuers to bring new ideas and higher our kids they've made take a chance on old broad. they are the ones that matter and when you kill a job and second when you have to cut taxes because then it since bad signals to job creators of they can cut might taxes to make it easier i am going the way then they need a fiscal plan bec

i was told alzheimer's and some other disease. you can't rob peter to pay paul spent our plans are dependent upon some of the supplement. >> again, i have other questions like notifying, you notify our dod that oversees personnel through state and dod. are there official notices going out on the risk and the warnings of? >> yes. we've been working closely with the other departments. >> we've got families and everybody all around the globe. i've got over my time. we will come back as we have got plenty of time as you can see with the members that are here. ms. duckworth, i will yield to you and thank you. >> thank you, mr. chairman. dr. schuchat, i wonder if i could deliver the chairman was like but in terms of notifying travelers as they coming back. i'm wondering about the travelers in the united states committee on the way out of what information is being provided. what the guidance was provided to devastated communities in the continental u.s. regarding zika? >> we been working closely with the clinical community including obst

the good news is that with a lot of things if you have alzheimer's, pancreatic cancer, there isn't much that can be done and you need to wait for the next discovery but for the vast majority of disorders, we only have enough to make the difference we just don't find it in an accessible way so i think that this is the only way that this kind of gets the attention of the media and the public and the government when there is violence into this so the individual that is mentally ill and not treated cows people. ..

just think if you took 10 trillion other than you hundred billion abedin expended on research on alzheimer's, just think if you took 100 billion evidence pentagon als are pancreatic cancer. but we can't seem to control this. when i was in washington we did and i will tell you the thing that is the most warring question is john kasich you are in the establishment. people who have known me that question is a joke. it is a flat-out joke. do you know what reagan was never in the establishment lane. i remember in 1976 when he ran against the establishment and they said he was a two bit actor and he was dominant he didn't know what he was doing. did do you know how he won? >> kit the door down. he told the establishment get out of my way and he used us to people as a battering ram to renew america. you see, this is happening because we don't have a leader who is able to get people to raise to a higher level. do you know why we won't balance the budget young lady? it only affects students, doctors, farmers, military people and who else can we go in there? everybody and you come exact way. so people

. >> the good news is as with a lot of things, if you have alzheimer's, pancreatic cancer, not much can be done. you have to wait for the next discovery. for the vast majority of mental disorders as i find them, we only have enough to make a huge difference, we just don't provide it in an accessible way. i think this is the only way this gets the attention of the media and government when there is a violent incident and some individual who is mentally ill, kills people. >> watch for these programs and more this weekend on booktv. on sunday march 6th, booktv is live with author and journalist jane mayer on in depth. our live monthly call in show. jane mayer's staff writer for the new yorker where she reports on government secrecy, the role of money and politics and u.s. counterterrorism policy. and her most recent book dark monday she reports on the political and economic underpinnings of the conservative movement with a focus on charles and david koch. .. they also declare the detainees are not criminals which kit rid of the criminal code. they're putting detainees in the legal limbo wh

accomplishments, all these cheerleaders and access permissions hence we need libraries not to have self-inflicted alzheimer's disease as a nation. they are there to remind us i appreciate him for several reasons. i was part of a committee that wanted to lure the academic term jim will be willing to join the university of texas faculty. it didn't happen unfortunately. kept through the university presidents there is another move to lower him into the university and that also didn't happen but what happened was the institute and that's what happened in the library of congress. i have to think about two things. many librarians dislike the fact that the nation's top positions go to librarians. that is a fact. the new york public library for most of it goes to historians and i propose the public library instead in order to repair the damage i would be happy to get the master of library science is and the unit in the move seeing these because it is natural and we must understand why historians are chosen for this position. one is in the cultural perspective and one is to go beyond the specialization and one you are

. >> the good news is if you have als, alzheimer's, or pancreas cancer, there is not much to be done. you wait for the next discovery. but for the vast majority of mental disorders we already have enough to make a huge difference. we just don't provide it. the only way this gets to aintention of the media is a mass violence incident. some individual who is mentally ill and untreated kills people. >> watch for these programs and more this weekend on booktv. >> a solicitor general of the united states supreme court. ryan owens is here to talk about it. what is the solicitor general? >> the solicitor general is the attorney for the united statess and represents the united states interest in the supreme court and occasionally the court of appeals. it is the central figure in terms of litigating the u.s.' position before the supreme court. >> whether or not that

or alzheimer's whether the bill that is on the agenda today is important, they would say yes. there were three -- four other bills that we enacted, one by senator isakson -- we didn't exact that we approved by committee, senator isakson and senator murphy on advancing research for neurological diseases, senator murray offered a bill to prevent superbugs and protecting patients based upon incidents that had happened in their home state of washington. and finally senator murray and i offered legislation that improved electronic medical records. our committee did not set out to deal with electronic medical records, but the more we got into our discussion -- we have used 25 minutes? the presiding officer: the senate wanted to be notified when he reached 20 minutes. he has reached 20. you still have the floor, senator. mr. alexander: thank you very much. i'll conclude my remarks. i see the senator from florida is here. but i would like to say this about the legislation senator murray and i introduced. the electronic medical records system in this country is in a ditch. doctors and

i was told alzheimer's and some other disease. you can't rob peter to pay paul spent our plans are dependent upon some of the supplement. >> again, i have other questions like notifying, you notify our dod that oversees personnel through state and dod. are there official notices going out on the risk and the warnings of? >> yes. we've been working closely with the other departments. >> we've got families and everybody all around the globe. i've got over my time. we will come back as we have got plenty of time as you can see with the members that are here. ms. duckworth, i will yield to you and thank you. >> thank you, mr. chairman. dr. schuchat, i wonder if i could deliver the chairman was like but in terms of notifying travelers as they coming back. i'm wondering about the travelers in the united states committee on the way out of what information is being provided. what the guidance was provided to devastated communities in the continental u.s. regarding zika? >> we been working closely with the clinical community including obst

she was on the alzheimer's caucus and she was the first residential candidate to have a position on autism and one reason she wants. they've been so people can take your family members to severe conditions. and she just makes she just make something good happen. secretary of state can tell you about that. i will say this. henry kissinger about people said she ran the state department that are about more of the personnel of the state in the state department that many secretary of state in decades and it's true. [cheers and applause] and she negotiated the iran sanctions and a treaty with russia took 67 votes in the senate. >> hillary went to flint michigan yesterday. and she talked about what a horrible moral failing what they are going through was. not just a financial one, but we have to do something. the most revealing answer to me as someone who's president, not her has been, to any question reflected well on both hillary and her opponent in terms of their values. at the end of the debate itself carolina, the moderator said is there anything we should have talked about that we haven't?

hence, we need libraries in order not to have self-inflicted alzheimer's disease as a nation. good libraries there -- are there to remind us always. second, as president of new york public library, i have to tell you that's where i get to know james really and appreciate him for several reasons. in 1968 when i joined faculty of university of texas at austin, i was part of a committee who wanted to lure -- that's a powerful academic team -- to lure or to send feelers to see whether jim will be willing to join university of texas faculty. well, it did not happen, unfortunately. for texas, fortunately for jim. and then i transfer to the university of pennsylvania, there's another move to lure jim billington to university of pennsylvania. that also did not happen. but what happened was woodrow wilson institute -- thank god -- and also what happened is library of congress. now, i have to confess that after i became president of new york public library, i realized two things about my position. many librarians dislike the fact that nation's top positions go to nonlibrarians. that's a

years from now we can look back and say that we have revolutionized medicine in areas like cancer, or alzheimer's, or some diseases that cause so much pain and suffering for so many families across the country, and there's no better place to do it than the united states of america, where r & d has been the hall mark or driving not only our economy but improvements we have seen in life expectancy and the quality of life for people all around the world. >> thank you. want to go now -- [applause] -- i want to start by talking about successes we have had, from people on the panel, in the realm of precision medicine and go to some of the challengees we face moving forward, starting with sonya, who several years ago your mother was diagnosed with a rare prion disease and passed away. the disease is known as fatal, insomnia. you have essentially devoted your life to making that name obsolete. you chose to get tested yourself. for the gene. how have you been motivated to be so pro-active? >> it's a great question. i would say deciding to get tested once i learned that my mom had died of a general nettic

mine was my mom had alzheimer's for 11 years, nine years of which she didn't speak and i was relatively well-informed citizen yet we didn't have all of those conversations before it was too late. we're working -- i guess i would like to assure that a commitment that we'll continue to work with your staff on the care planning codes, how we look at more wrap around services. we're trying to work to make sure that these type of advanced directives can actually travel across state lines because so many loved ones, even if you move forward with this documentation, i know this is something that senator wyden has been engaged in as well. mom and dad and aunts and uncles move. trying to make sure that those documents travel with you built into your emr. i would like your comments in this space and again acknowledging that we have, i think for the most part, elected officials have to move beyond some of the horrific language that may have been used six or seven years ago. this is a part of everyone's life and it needs to be dealt with and dealt with appropriately. my hope is that the care planni

and they are currently working on imaging systems to identify alzheimer's in its earliest stages. it's an incredible operation. this commitment will pay us back many times over. and i yield to my friend and colleague from tennessee. mr. alexander: the senator from tennessee. mr. alexander: mr. president, i urge a yes vote because i think an important part of a republican pro-growth policy is support for government-sponsored research. that's how we got 3-d mapping and horizontal drilling that led to unconventional gas and oil. that's how we're going to get the cost of carbon capture low enough to make it commercial. it's how we're going to get solar panels cheap enough to make them useful. we can reduce wasteful spending on subsidies for mature energy technology and double energy research, and this would do that on a conservative path. at 5% a a year, it would take ten years to double the energy spending we have today. i urge a "yes" vote. ms. murkowski: mr. president? the presiding officer: the senator alaska. ms. murkowski: mr. president, i understand that we have an agreement to