In this paper, we present a new design for a multiple-input multiple-output (MIMO) antenna with four ports operating in wide and multi-millimeter-wave (Mm-Wave) bands for various 5G applications (including the internet of things (IoT), communication devices, and smartphones). The antenna is designed in a rectangular zigzag shape with slots to make the antenna operate at different frequencies. For this, the antenna operates at multiple frequencies from 38 to 62 GHz, so it supports all advanced wireless communication applications. The most important characteristic of the design is its small size and compact structure compared to designs presented by researchers in previous literature so the antenna dimensions for four elements are 29×49 mm2 . The antenna performance based on the results obtained from CST Studio Suite is good since the reflection coefficients of the antenna resonate at six main frequencies are 39.128 GHz, 42.992 GHz, 47.384 GHz, 51.536 GHz, 55.472 GHz, and 59.288 GHz. In addition, the isolation value between all antenna elements is ≤30 dB and the diversity gain value for all frequencies is 10 dB. Moreover, a very small value was obtained for the envelope correlation coefficient (ECC) is <4.0576 × 10−11 . Finally, the results indicate a favorable design and potential competitor for all 5G MIMO Mm-Wave applications.